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Gallbladder cancer may be linked to estrogens, says UH team
Date:8/16/2010

may be responsible for this particular cancer, indicating a higher risk for this disease. This, in turn, could one day be used to determine individual risks.

"Going forward, we need to estimate exactly the levels of LXRβ and its activators in human gallbladder cancers, particularly in female patients," Gustafsson said. "Once the presence and the function of LXRβ in the human gallbladder are clear, we are going to test the potential effects of LXRβ molecules on human gallbladder cancer cells."

In addition to Gustafsson, the UH team on this project consists of post-doctoral students Drs. Chiara Gabbi, who made the discovery, Hyun-Jin Kim and Rodrigo Barros, as well as biology and biochemistry professor Margaret Warner, who has worked with the Gustafsson group since 1986. Marion Korach-Andre' from the Center for Biosciences at the Karolinska Institute in Sweden also contributed to this study.


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Contact: Lisa Merkl
lkmerkl@uh.edu
713-743-8192
University of Houston
Source:Eurekalert  

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