Navigation Links
Galapagos and Cystic Fibrosis Foundation Therapeutics announce drug discovery collaboration
Date:11/29/2007

Mechelen, Belgium and Bethesda, Maryland, USA; 29 November 2007 Galapagos NV (Euronext & LSE: GLPG) and Cystic Fibrosis Foundation Therapeutics, Inc. (CFFT), the non-profit affiliate of the Cystic Fibrosis Foundation, announced today a new collaboration aimed at discovering new treatments for cystic fibrosis. This new agreement between CFFT and Galapagos BioFocus DPI service division is worth up to 5.5 million euros ($8.1 million U.S. dollars) for Galapagos.

The collaboration will combine two key strengths of BioFocus DPI expertise in natural product drug discovery and screening in cells derived from patients. Specifically, the collaboration aims to identify small molecules derived from natural sources that improve the function of a defective protein found in people who have cystic fibrosis. The protein is called CFTR - cystic fibrosis transmembrane conductance regulator. To advance the search for a cure for cystic fibrosis, CFFT funds promising scientific research in the pharmaceutical and biotechnology industry and academia worldwide.

Under the terms of the agreement, Galapagos stands to receive up to 1.6 million ($2.4 million) in upfront and research fees over the next two years, and up to 3.8 million ($5.7 million) in success-based milestone payments, should certain clinical development criteria be met.

This drug discovery collaboration is in addition to an ongoing target discovery program established between CFFT and BioFocus DPI in April 2005.

We are excited to take advantage of the innovative drug discovery approach developed by BioFocus DPI and the companys extensive expertise in natural compounds, said Robert J. Beall, Ph.D., President and CEO of the Cystic Fibrosis Foundation. By exploring compounds derived from natural sources, our goal is to increase the number and diversity of drug candidates in development to treat cystic fibrosis.

The CFFT drug discovery collaboration is a prime example o
'/>"/>

Contact: Lily Mccutchan
lmccutchan@cff.org
301-841-2674
Cystic Fibrosis Foundation
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. Cystic fibrosis patients may breathe easier, thanks to bioengineered antimicrobials
2. Balzan Foundation announces 2007 winners
3. Keck Foundation funds study of biological interactions with nanomaterials
4. Yu receives research funding from the Wallace H. Coulter Foundation
5. PETA awards $120,000 to Duluth Foundation for advancing non-animal tests
6. Simons Foundation awards Emory scientists $3M for autism gene research
7. Arizona State University launches biofuel initiative with BP and Science Foundation Arizona
8. Life-saving clean water project secures $13M from Bill & Melinda Gates Foundation
9. Selexis Announces Advanced Approach to Maximize Power of Genetic Elements for Rapid Development of High Performance Cell Lines
10. LaserCard Corporation Announces Expansion of Middle East Project
11. BIO-key(R) Announces Contracts for New Criminal Justice Data Sharing Solution

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/23/2009)...d USDA study concluded that 50 million U.S. acres ...ould be converted from current uses to the product...m which biomass could be harvested for use as a bi... a perennial grass monoculture from which substant...expected to require nitrogen fertilizer. , An ag...
(Date:11/23/2009)...ies about the multiple health benefits of vitamin ...ent, increased awareness of the huge numbers of pe... even led to an appreciation of it as "nature,s an...f your immune system to prevention of heart diseas...s now seen as one of the most critical nutrients f...
(Date:11/23/2009)...e for Child Health Research has found evidence tha...pregnancy affects child behaviour in different way... the international journal Addiction . , Lead a...from a random sample of more than 2000 mothers who...baby,s delivery, and were then followed up when th...
Breaking Biology News(10 mins):Switchgrass produces biomass efficiently 2Multiple health concerns surface as winter, vitamin D deficiences arrive 2Multiple health concerns surface as winter, vitamin D deficiences arrive 3New study links alcohol in pregnancy to child behavior problems 2Rebecca Mader to Illuminate UNICEF Snowflake at Lighting Ceremony in Beverly Hills 61145 1Rebecca Mader to Illuminate UNICEF Snowflake at Lighting Ceremony in Beverly Hills 61145 2Rebecca Mader to Illuminate UNICEF Snowflake at Lighting Ceremony in Beverly Hills 61145 3Conference of International Experts Calls for a Focus on Well Being and The Person in Health 61140 1Conference of International Experts Calls for a Focus on Well Being and The Person in Health 61140 2Conference of International Experts Calls for a Focus on Well Being and The Person in Health 61140 3WellTek MedX Group Completes Major Reorganization 6168 1WellTek MedX Group Completes Major Reorganization 6168 2
...cember 4, 2008.- La enciclopedia de las aves de E...nd SEO/BirdLife, is intended as an introduction fo... birds. This interactive, multimedia publication o...n 500 bird species that reside, visit or have been...atterns and the threats that confront them. , As ...
...rrent government policy is failing to protect trad...lien van Rij. Green areas in the Randstad region w...specific agricultural policy is developed for them...and sufficient legislation from the Dutch governme...ovements to rules and policy programmes for green ...
...N ARBOR, Mich. In a new study led by the Universi...led their fruit and vegetable intakes and dramatic...en they were counseled by registered dietitians an... of certain foods they should eat each day. , The...nts into two groups. In one group, registered diet...
Other Biology News:The birds of Spain, in a digital ornithological encyclopedia 2The birds of Spain, in a digital ornithological encyclopedia 3The birds of Spain, in a digital ornithological encyclopedia 4Traditional Dutch landscape under threat 2Women double fruit, veggie intake with switch to Mediterranean diet plan 2Women double fruit, veggie intake with switch to Mediterranean diet plan 3
(Date:11/24/2009)...,, DUBLIN,November24/PRNewswire-FirstCall/--Shi...iopharmaceuticalcompany,today,announcedthatithassu...cerasealfa,thecompany,senzymereplacementtherapyind...isisthethirdmarketing,applicationforvelaglucerasea...theUnitedStatesandCanada. , Basedonaglobalsup...
(Date:11/24/2009)...,, BOZEN,Italy,November24/PRNewswire/--HealthRo...intventurewithagroupofselected,investors.Thisrecen...ameHealthRoboticsCanada,Inc.andwillmarket,install,...pt,whichincludesthe,revolutionaryproductofferingsi...ticsCanadaInc.willalsoprovideassistanceonan"asneed...
(Date:11/24/2009)...,, SEATTLE,Nov.24/PRNewswire-FirstCall/--CellTh...illpresentatthe21stAnnualPiperJaffrayHealthCareCon...theNewYorkPalaceHotel. ,, CTIwillpresentonTuesd...or).AliveaudiowebcastofCTI,spresentationwillbeavai...vailableforreplayafterwards. , ,PiperJaffrayHealt...
(Date:11/23/2009)...Quantum computing promises ultra-fast communicatio...ensitive information. But trying to use quantum st...licate business. Now two physicists have shown, ma...ts in quantum communication, while keeping the inf...rent issue of Physical Review Letters and highli...
Breaking Biology Technology:Shire Submits European Marketing Authorization Application (MAA) for velaglucerase alfa for the Treatment of Type 1 Gaucher Disease 2Shire Submits European Marketing Authorization Application (MAA) for velaglucerase alfa for the Treatment of Type 1 Gaucher Disease 3Health Robotics Continues its Global Expansion With December 09 ASHP's Launch of Joint Venture in Canada 2
...Both Ears for the First Ti...he world,s leader in,advanced hearing technologies...omas Roland, Jr., MD of NYU Langone Medical Center...ocedure. Today, 72-year-old New York,resident, Sus...eral (a,device in each ear) Nucleus(R) Freedom coc...
...eativity, sponsored by the Jerusalem-based Project...evealed that a majority of the Israeli scientists ...ods that could "put them into a creative stat...ed." , Jerusalem, Is...reativity, sponsored by the Jerusalem-based www.p...
...: NUVA ), a medical device company focused on dev... treatments for the spine, announced today,that it...n of the Osteocel,biologics business from Osiris T... in cash, plus additional milestone-based continge...sh or stock, at NuVasive,s election. The,core of t...
Other Biology Technology:Cochlear Announces Milestone in Hearing Restoration With 120,000 Nucleus(R) Cochlear Implants 2Cochlear Announces Milestone in Hearing Restoration With 120,000 Nucleus(R) Cochlear Implants 3Cochlear Announces Milestone in Hearing Restoration With 120,000 Nucleus(R) Cochlear Implants 4Project Mind Survey of Israeli Ph.D. Scientists Favors a New Standard of Creativity in Science 2Project Mind Survey of Israeli Ph.D. Scientists Favors a New Standard of Creativity in Science 3NuVasive Completes Acquisition of Osteocel Biologics Business 2NuVasive Completes Acquisition of Osteocel Biologics Business 3NuVasive Completes Acquisition of Osteocel Biologics Business 4NuVasive Completes Acquisition of Osteocel Biologics Business 5
...Slide is designed for heavy duty short stroke appl...substantial side-loading is present. Standard pist...s of trouble-free cycles even in high speed applic...lating ball bearings , Optional corrosion resistan...
Normal Hamster Serum - 50mL from GeneTex
Alkaline Phosphatase (E. coli C75) from GE Healthcare, formerly Amersham Biosciences
... System - dCTP with CyScribe GFX Purification Kit,... of Cy3- and Cy5-labeled cDNA.Optimized reagents a...d purification.Flexible and optimized protocols ca...ither Cy3- or Cy5-labeled nucleotides.Reliable pur...
Biology Products: