Navigation Links
GW researcher invents 'mini heart' to help return venous blood
Date:3/27/2014

WASHINGTON (March 27, 2014) George Washington University (GW) researcher Narine Sarvazyan, Ph.D., has invented a new organ to help return blood flow from veins lacking functional valves. A rhythmically contracting cuff made of cardiac muscle cells surrounds the vein acting as a 'mini heart' to aid blood flow through venous segments. The cuff can be made of a patient's own adult stem cells, eliminating the chance of implant rejection.

"We are suggesting, for the first time, to use stem cells to create, rather than just repair damaged organs," said Sarvazyan, professor of pharmacology and physiology at the GW School of Medicine and Health Sciences. "We can make a new heart outside of one's own heart, and by placing it in the lower extremities, significantly improve venous blood flow."

The novel approach of creating 'mini hearts' may help to solve a chronic widespread disease. Chronic venous insufficiency is one of the most pervasive diseases, particularly in developed countries. Its incidence can reach 20 to 30 percent in people over 50 years of age. It is also responsible for about 2 percent of health care costs in the United States. Additionally, sluggish venous blood flow is an issue for those with diseases such as diabetes, and for those with paralysis or recovering from surgery.

This potential new treatment option, outlined in a recently published paper in the Journal of Cardiovascular Pharmacology and Therapeutics, represents a leap for the tissue engineering field, advancing from organ repair to organ creation. Sarvazyan, together with members of her team, has demonstrated the feasibility of this novel approach in vitro and is currently working toward testing these devices in vivo.


'/>"/>
Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University
Source:Eurekalert

Page: 1

Related biology news :

1. Clemson researcher touts surgical safety checklist to save lives
2. Researchers at IRB discover a key regulator of colon cancer
3. Researchers reveal the dynamics behind Arctic ecosystems
4. IRCM researchers uncover a new function for an important player in the immune response
5. UGA researchers explore function of cancer-causing gene
6. Distinguished researcher to speak at NJIT on preventing bone loss
7. Researchers present comprehensive roadmap of blood cells
8. UT Southwestern ob/gyn researchers studying genetic factors in premature births
9. Researchers issue state-of-the-state on genetic-based testing & treatment for breast cancer
10. Heidelberg researcher awarded Animal Welfare Prize of the German Research Foundation
11. Miscarriage clues identified in new DNA test according to researchers at Montefiore and Einstein
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... atmospheric scientists were instrumental in the creation of the ... to classify the fire threat potential of the powerful, ... spark into an inferno. The index was introduced Sept. ... UCLA and San Diego Gas and Electric. , The ... "extreme" that will be used to help fire agencies ...
(Date:9/17/2014)... engineering professor and his doctoral student have designed a ... water collected from fog and dew., The device could ... deserts around the globe., Cheng Luo, professor in the ... candidate in the same College of Engineering department, published ... of ACS, (American Chemical Society) Applied Materials ...
(Date:9/17/2014)... 17, 2014) A rare genetic disorder known as Jacobsen ... recent joint investigation by researchers at San Diego State ... addition to suggesting better treatment options for people with ... the genetic underpinnings of autism., Jacobsen syndrome affects approximately ... of Health. It occurs in a person when there ...
Breaking Biology News(10 mins):UCLA scientists play key role in developing new Santa Ana Wildfire Threat Index 2Shorebird's beak inspires UT Arlington research on water collection 2A link between Jacobsen syndrome and autism 2
... cells in the eye receptive to light is missing in ... animals like birds, fish and amphibians have two versions of ... The findings ?published in the Public Library of Science journal ... may be impoverished compared to other vertebrates and fits with ...
... Waiting a day or more to get lab results back ... a past. Using nanotechnology, a team of University of Georgia ... as diverse as influenza, HIV and RSV in 60 seconds ... ?which is detailed in the November issue of the journal ...
... 12, 2006 -- A new study in Journal of the ... over smaller shrimp of the same gender when competing for ... though adult males of the species are typically much smaller ... size and gender are important factors in acquiring food," says ...
Cached Biology News:Does missing gene point to nocturnal existence for early mammals? 2Silver bullet: UGA researchers use laser, nanotechnology to rapidly detect viruses 2Silver bullet: UGA researchers use laser, nanotechnology to rapidly detect viruses 3
(Date:9/19/2014)... rather than electricity, to move data would consume ... a growing concern as chips, transistor counts rise. ... circuits light emitters, modulators, and detectors ... light source for optical chips is molybdenum disulfide ... as a single, atom-thick layer. Other experimental on-chip ...
(Date:9/19/2014)... , Sept. 19, 2014 Pfenex Inc. ... the development of high-value and difficult to manufacture proteins ... presenting at the 21 st Annual NewsMakers in ... . Bertrand Liang , chief executive officer ... development programs and business strategy on Friday, September 26, ...
(Date:9/19/2014)... , September 19, 2014 ... 53rd European Society for Paediatric Endocrinology (ESPE) Meeting  ... science and medical research in the field of growth  ... KGaA, Darmstadt, Germany , today announced ... (GGI) for 2014. The awards were announced during a ...
(Date:9/18/2014)... Sept. 18, 2014 /PRNewswire-iReach/ -- DeepResearchReports.com adds "2014 ... Acid Industry" and "2014 Deep Research Report on ... its research database. Photo - ... Report on Global and China Acetic Acid Industry" ... China and Global Acetic ...
Breaking Biology Technology:Toward optical chips 2Toward optical chips 3Pfenex to Present at Upcoming Industry Conference on September 26 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 2Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 4
... , , SAN DIEGO , ... BMR ) today announced the signing of an amendment to its ... 301 Binney Street laboratory research facility in Cambridge, Massachusetts . ... laboratory and office space contiguous to its existing premises located in ...
... , , ... Reportlinker.com announces that a new market research ... The Future of Nutrigenomics: New opportunities in ... http://www.reportlinker.com/p0177850/The-Future-of-Nutrigenomics-New-opportunities-in-personalized-nutrition-and-food-pharma-collaboration.html , Nutrigenomics explores how nutrients ...
... , CRANBURY, N.J. , Feb. 16 ... for its second quarter ended December 31, 2009 .  Palatin reported net ... diluted share, for the quarter ended December 31, 2009 , compared to ... basic and diluted share, for the same period in 2008.  Total revenues in ...
Cached Biology Technology:BioMed Realty Trust Expands Lease With Ironwood Pharmaceuticals for 50,000 Square Feet in Cambridge, Massachusetts 2BioMed Realty Trust Expands Lease With Ironwood Pharmaceuticals for 50,000 Square Feet in Cambridge, Massachusetts 3BioMed Realty Trust Expands Lease With Ironwood Pharmaceuticals for 50,000 Square Feet in Cambridge, Massachusetts 4Reportlinker Adds The Future of Nutrigenomics: New opportunities in personalized nutrition and food-pharma collaboration 2Reportlinker Adds The Future of Nutrigenomics: New opportunities in personalized nutrition and food-pharma collaboration 3Reportlinker Adds The Future of Nutrigenomics: New opportunities in personalized nutrition and food-pharma collaboration 4Reportlinker Adds The Future of Nutrigenomics: New opportunities in personalized nutrition and food-pharma collaboration 5Reportlinker Adds The Future of Nutrigenomics: New opportunities in personalized nutrition and food-pharma collaboration 6Palatin Technologies, Inc. Reports Second Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on February 16, 2010 2Palatin Technologies, Inc. Reports Second Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on February 16, 2010 3Palatin Technologies, Inc. Reports Second Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on February 16, 2010 4Palatin Technologies, Inc. Reports Second Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on February 16, 2010 5Palatin Technologies, Inc. Reports Second Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on February 16, 2010 6Palatin Technologies, Inc. Reports Second Quarter Fiscal Year 2010 Results; Teleconference and Webcast to be held on February 16, 2010 7
... NightOWL is a dedicated imaging system ... size. Equipped with a very sensitive camera ... or plants in tumor research, infectious disease ... Western blots. NightOWL is the only imager ...
Mouse monoclonal antibody raised against a partial recombinant COG2. NCBI Entrez Gene ID = COG2...
Mouse polyclonal antibody raised against a partial recombinant AGTRAP. NCBI Entrez Gene ID = 57085...
Mouse polyclonal antibody raised against a partial recombinant NCLN. NCBI Entrez Gene ID = 56926...
Biology Products: