Navigation Links
GW professor to examine infections in HIV patients with federal grant
Date:11/26/2012

WASHINGTON (Nov. 26, 2012) Imtiaz A. Khan, M.D., professor of microbiology, immunology, and tropical medicine at the George Washington University School of Medicine and Health Sciences, received a $1.6 million federal grant from the National Institute of Allergy and Infectious Diseases to study the effects of microsporidiaopportunistic inter-cellular pathogensthat cause morbidity and mortality in HIV patients.

Fifteen years ago, Khan saw that this type of infection was becoming a major problem in HIV populations. He realized little had been researched about immune response to these pathogens. After looking into the matter further, he saw that CD8+ T cells played a critical role in protecting against these pathogens.

His project, titled "CD8+ T cell effectors against microsporidia," will study how to prevent microsporidia from causing complications in immunocompromised subjects by regulating CD8+ T cells. These highly understudied cells are tolerated and controlled in healthy, immunocompetent individuals. For the elderly or individuals with HIV, these cells can cause problems. In order to stave off infection for the immunocompromised, the cells need to be maintained and regenerated.

"The question is, how can you generate CD8 effectively, so this infection does not harm them?" said Khan. "Because CD8+ T cells are critical, how can you maintain a good CD8 cell population, so this group of pathogens doesn't reemerge?"

Khan and his research team will be using cytokines and other therapeutic methods to generate highly functional CD8+ T cells to create and maintain robust immunity against these pathogens, improving the mortality and quality of life of many HIV patients.

This research may not only benefit those suffering from microspordia, but can be extended to other infections effecting HIV populations, as well.


'/>"/>

Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University
Source:Eurekalert

Page: 1

Related biology news :

1. Michael Barnett of Boston College named Professor of the Year for Massachusetts
2. NJIT professor promotes building material of millennium: Autoclave aerated concrete
3. The IPCC Report on Climate Change - Swedish professor Thomas Sterner selected as 1 of the experts
4. Louisiana Tech University professor earns national honor from Society of American Foresters
5. New book on physics principles by Wayne State professor explains life as we know it
6. SMU professor Louis Jacobs honored with prestigious award from Texas science teachers
7. Professor publishes on first-ever imaging of cells growing on spherical surfaces
8. UA engineering professor Shane Snyder to speak in Korea on international water quality
9. National herpetology society honors UT Arlington professor for discoveries
10. GW professor receives grant to study the role of genes in drug addiction
11. Professors Antarctica research shows potential king crab invasion
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/30/2016)...  higi SH llc (higi) announced today the ... brands, industry thought-leaders and celebrity influencers looking to ... taking steps to live healthier, more active lives. ... has built the largest self-screening health station network ... who have conducted over 185 million biometric screenings.  ...
(Date:11/24/2016)... , Nov. 23, 2016 Cercacor today ... athletes and their trainers non-invasively measure hemoglobin, ... Pulse Rate, and Respiration Rate in approximately 30 seconds. ... users easy and immediate access to key data about ... of a training regimen. Hemoglobin carries ...
(Date:11/17/2016)... Global Market Watch: Primarily supported by ownership types; ... Academics) market is to witness a value of US$37.1 billion ... Compounded Annual Growth Rate (CAGR) of 10.75% is foreseen from ... 2014-2020. North America is not way ... Europe at 9.56% respectively. Report Focus: ...
Breaking Biology News(10 mins):
(Date:12/8/2016)... Philadelphia, PA (PRWEB) , ... December 08, 2016 ... ... fan engagement platforms, the business of innovation is taking over sports. On Thursday, ... executive will explore how technology is disrupting the playing field at a Smart ...
(Date:12/8/2016)...  Biotheranostics today announced that new data will ... Cancer Index (BCI) in identifying which patients with ... for disease recurrence and might benefit from extended ... advancing the understanding of the value of BCI ... inform decisions related to patient treatment. These data ...
(Date:12/8/2016)... Dec. 8, 2016 Eurofins announces the appointment of ... of Eurofins Scientific Inc. (ESI). Mr. Murray will ... professional and entrepreneurial experience in leading international business teams. As the ... testing market to uphold Eurofins, status as the global leader in ... , ...
(Date:12/8/2016)... ... December 08, 2016 , ... Opal Kelly, a ... device-to-computer interconnect using USB or PCI Express, announced the FOMD-ACV-A4, the company's first ... a small, thin, SODIMM-style module that fits a standard 204-pin SODIMM socket for ...
Breaking Biology Technology: