Navigation Links
GW professor to examine infections in HIV patients with federal grant
Date:11/26/2012

WASHINGTON (Nov. 26, 2012) Imtiaz A. Khan, M.D., professor of microbiology, immunology, and tropical medicine at the George Washington University School of Medicine and Health Sciences, received a $1.6 million federal grant from the National Institute of Allergy and Infectious Diseases to study the effects of microsporidiaopportunistic inter-cellular pathogensthat cause morbidity and mortality in HIV patients.

Fifteen years ago, Khan saw that this type of infection was becoming a major problem in HIV populations. He realized little had been researched about immune response to these pathogens. After looking into the matter further, he saw that CD8+ T cells played a critical role in protecting against these pathogens.

His project, titled "CD8+ T cell effectors against microsporidia," will study how to prevent microsporidia from causing complications in immunocompromised subjects by regulating CD8+ T cells. These highly understudied cells are tolerated and controlled in healthy, immunocompetent individuals. For the elderly or individuals with HIV, these cells can cause problems. In order to stave off infection for the immunocompromised, the cells need to be maintained and regenerated.

"The question is, how can you generate CD8 effectively, so this infection does not harm them?" said Khan. "Because CD8+ T cells are critical, how can you maintain a good CD8 cell population, so this group of pathogens doesn't reemerge?"

Khan and his research team will be using cytokines and other therapeutic methods to generate highly functional CD8+ T cells to create and maintain robust immunity against these pathogens, improving the mortality and quality of life of many HIV patients.

This research may not only benefit those suffering from microspordia, but can be extended to other infections effecting HIV populations, as well.


'/>"/>

Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University
Source:Eurekalert

Page: 1

Related biology news :

1. Michael Barnett of Boston College named Professor of the Year for Massachusetts
2. NJIT professor promotes building material of millennium: Autoclave aerated concrete
3. The IPCC Report on Climate Change - Swedish professor Thomas Sterner selected as 1 of the experts
4. Louisiana Tech University professor earns national honor from Society of American Foresters
5. New book on physics principles by Wayne State professor explains life as we know it
6. SMU professor Louis Jacobs honored with prestigious award from Texas science teachers
7. Professor publishes on first-ever imaging of cells growing on spherical surfaces
8. UA engineering professor Shane Snyder to speak in Korea on international water quality
9. National herpetology society honors UT Arlington professor for discoveries
10. GW professor receives grant to study the role of genes in drug addiction
11. Professors Antarctica research shows potential king crab invasion
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)... NEW YORK , June 2, 2016   The ... (Weather), is announcing Watson Ads, an industry-first capability in which ... advertising, by being able to ask questions via voice or ... Marketers have long ... with the consumer, that can be personal, relevant and valuable; ...
(Date:6/1/2016)... , June 1, 2016 ... in Election Administration and Criminal Identification to Boost Global ... a recently released TechSci Research report, " Global Biometrics ... Region, Competition Forecast and Opportunities, 2011 - 2021", the ... billion by 2021, on account of growing security concerns ...
(Date:5/20/2016)... MINNEAPOLIS , May 20, 2016  VoiceIt ... technology partnership with VoicePass. By working ... user experience.  Because VoiceIt and VoicePass take slightly ... two engines increases both security and usability. ... expressed excitement about this new partnership. ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... ... 2016 , ... Mosio, a leader in clinical research patient ... and Retention Tips.” Partnering with experienced clinical research professionals, Mosio revisits the hurdle ... and strategies for clinical researchers. , “The landscape of how patients receive and ...
(Date:6/23/2016)... , June 23, 2016 A person commits ... the crime scene to track the criminal down. ... U.S. Food and Drug Administration (FDA) uses DNA evidence to ... Sound far-fetched? It,s not. The FDA has ... to support investigations of foodborne illnesses. Put as simply as ...
(Date:6/23/2016)... NEW YORK , June, 23, 2016  The ... students to envision new ways to harness living systems ... of Modern Art (MoMA) in New York ... more than 130 participating students, showcased projects at MoMA,s ... included Paola Antonelli , MoMA,s senior curator of ...
(Date:6/23/2016)... ... ... In a new case report published today in STEM CELLS Translational Medicine, doctors ... being treated for breast cancer benefitted from an injection of stem cells derived from ... frequent side effect of cancer treatment. , Lymphedema refers to the swelling ...
Breaking Biology Technology: