Navigation Links
GW and Peking University awarded funding to understand common blood coagulation disorder
Date:7/15/2014

WASHINGTON -- The George Washington University (GW) School of Medicine and Health Sciences (SMHS) and The Peking University Medical College in Beijing, China are pleased to announce the award of significant funding for an international co-operative project to understand the molecular mechanisms of a very common blood coagulation disorder affecting both Americans and Chinese.

Research and medical teams from GW and Peking University Medical College will work together to apply the most sophisticated next-generation DNA/RNA sequencing to the problem of aspirin-insensitive thrombophilia. While aspirin is the most commonly used preventative therapy for heart disease, a certain fraction of subjects do not benefit from treatment, sometimes called aspirin resistance (AR).

In prior studies, GW scientists Drs. Tim McCaffrey, Sidney Fu, and Ian Toma in the Division of Genomic Medicine, worked closely with GW physicians Drs. Richard Katz, Jonathon Reiner, and Ramesh Mazhari, to identify RNA transcripts in blood that might help to explain this dangerous disease. It was known that patients with AR are up to 10 times more likely to have a heart attack than patients who respond normally to aspirin. That danger could be further increased when the patients undergo coronary stenting, which places a polymer coated wire mesh into the coronary arteries.

"This is a very important study that will improve the safety of many patients. By studying patients with AR, doctors will eventually be able identify a different course of treatment or prevention to be used for those with the disease," said McCaffrey, Ph.D., director of the Division of Genomic Medicine at SMHS.

Using sophisticated genomic microarrays, the GW team identified an interesting pattern of gene expression that suggested the coagulation disorder could be due to some type of autoimmune disease, in which the patient's own antibodies are attacking their blood platelets.

The
'/>"/>

Contact: Lisa Anderson
lisama2@gwu.edu
202-994-3121
George Washington University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Marshall University to partner with international company in drug development venture
2. Scorpions are master architects, according to new research from Ben-Gurion University
3. University of Strathclyde and NYU join in landmark research and academic partnership
4. Washington Universitys Joseph Jez is one of 15 million dollar professors
5. University of Tennessee discoveries could help neutralize chemical weapons
6. US housing policies increase carbon output, Georgia State University research finds
7. Mountain ecosystems scientists to convene at University of Nevada, Reno
8. University of Toronto biologists pave the way for improved epilepsy treatments
9. Chapman University partners with the Center for Autism and Related Disorders
10. Global health grant from the Bill & Melinda Gates Foundation awarded to the University of Surrey
11. Wayne State University licenses technology to new start-up, Detroit Materials, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... MADISON, Wis. , Jan. 15, 2015  BellBrook ... for drug discovery, announced the launch of a ... of the company,s Transcreener UDP Assay, a high ... enzymes. The new assay will allow for sensitive ...
(Date:1/22/2015)... , Jan. 20, 2015 NXT-ID, Inc. (NASDAQ: NXTD ... commerce market, reports on the recent success of the Wocket™ smart wallet ... Wocket smart wallet was named as one of the "11 Hot ... "5 Best Products Launched At CES So Far" by Newseveryday.com and "The ...
(Date:1/22/2015)... NEW YORK , Jan. 21, 2015  Analyst Report Issued ... Credit Card Brands report showed that planet-wide, transactions at merchants ... 2011, while the total number of credit, debit, and prepaid ... the U.S. were victims of fraudulent card usage in 2012, ...
Breaking Biology News(10 mins):BellBrook Labs Launches a High Throughput Screening Assay for Glycosyltransferases with TR-FRET Readout 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3$4.80 Near Term Price Target with "Buy" given by CapRock Research for NXT-ID, Inc. (NASDAQ: NXTD) issued by Small Cap IR 2
... Germany, April 29, 2009 / b3c newswire / - ... Target Profiling® technology to identify the protein kinase ... (Celebrex®, Pfizer). Celecoxib is a non-steroidal, anti-inflammatory Cox-2 ... arthritis and acute pain. In addition, celecoxib’s anti-proliferative ...
... Danforth Plant Science Center have received two awards totaling ... to do research on novel energy initiatives. At ... ever received on the Danforth Campus. The $15 million ... largest the organization has ever received. Washington University ...
... a seminar at another institution several years ago, ... hostile question: Why bother classifying organisms according to ... dynamics, when molecular techniques had already invalidated that ... in the audience nodding their agreement, Jablonski, the ...
Cached Biology News:KINAXOs Cellular Target Profiling reveals mTOR as a new target of Celebrex 2DOE makes largest Danforth Campus research award in history 2DOE makes largest Danforth Campus research award in history 3DOE makes largest Danforth Campus research award in history 4DOE makes largest Danforth Campus research award in history 5Analysis finds strong match between molecular, fossil data in evolutionary studies 2
(Date:1/22/2015)... OH (PRWEB) January 22, 2015 Crystal Diagnostics ... today that it has received AOAC-PTM Certifications for the six ... O121, and O145; collectively referred to as STEC or the ... 1 colony forming unit (cfu) per 325 g of raw ...
(Date:1/22/2015)... 2015 Dr. Greg Leyer of UAS Labs ... Natural Supplements Pre-Conference seminar on probiotics in San Diego, CA. ... continuing education conference for health care professionals. This year’s pre-conference ... of probiotics in health. Dr. Leyer spoke about the emerging ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Diagenode, ... such as the Bioruptor® and complete solutions for ... for chromatin immunoprecipitation, alleviating the need for manual ... controls needed for ChIP of histones or transcription ...
(Date:1/22/2015)... Calif. , Jan. 22. 2015  Varian Medical Systems (NYSE: ... software, has been honored for its commitment to sustainability with ... companies. Varian is the highest ranked healthcare equipment company among ... today during the World Economic Forum at Davos, ...
Breaking Biology Technology:Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2Diagenode Launches Unique Semi-Automated Solution for Chromatin Immunoprecipitation 2Varian Honored Among World's 100 Most Sustainable Corporations 2
... 10, 2009, NeoStem, Inc. (NYSE Alternext US: NBS) (the ... "Alternext") indicating that the Company is not in compliance ... "Guide"), which requires a listed company to hold meetings ... Company had announced that it planned to hold a ...
... ITMN ) today announced the pricing of an underwritten ... The last reported sale price of InterMune,s common stock on ... $17.96. The offering is expected to close on or ... All of the shares are being sold by the company.UBS ...
... Pharmacyclics, Inc.,(Nasdaq: PCYC ) today reported financial ... net loss for the second quarter of fiscal 2009,was $4.8 ... of $5.9 million,or $0.23 per share, in the second quarter ... expenses were $4.9 million in the second quarter of fiscal,2009, ...
Cached Biology Technology:NeoStem Receives Notice of Noncompliance from NYSE Alternext US 2InterMune Announces Pricing of Public Offering of 3,500,000 Shares of Common Stock 2Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 2Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 3Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 4Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 5Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 6Pharmacyclics Reports Second Quarter Fiscal 2009 Financial Results 7
TEMPLIPHI HT SEQ AMPL KIT, 1 EA. Category: Sequencing Template Amplification....
... Vybrant Apoptosis Assay Kit #4 ... that occur in the permeability of cell ... both YO-PRO-1 and propidium iodide nucleic acid ... plasma membranes of apoptotic cells and labels ...
Request Info...
5-bromo-4-chloro-3-indolyl b -D-galactopyranoside (X-Gal)...
Biology Products: