Navigation Links
GEN reports on rediscovered technology to bolster proteomics research
Date:8/13/2010

New Rochelle, NY, August 13, 2010Scientists are turning to a decades-old technique to better understand the physical effects of compression on macromolecules and how it might impact their research in proteomics, mass spectrometry, protein extraction, and tissue investigations, reports Genetic Engineering & Biotechnology News (GEN). These studies are built upon the early ultrahigh pressure discoveries of the late Nobel Prize winner in Physics, Percy Bridgman, Ph.D., who was a professor at Harvard from 1908 to 1954, according to the August issue of GEN (http://www.genengnews.com/gen-articles/use-of-ultrahigh-pressure-on-the-rise/3360).

"Pressure-cycling technology (PCT) has definitely caught the attention of an increasing number of scientists," says John Sterling, Editor in Chief of GEN. "In addition, researchers no longer need to construct their own tools because instruments such as the Barocycler from Pressure Biosciences are now available."

Zoltan Szabo, Ph.D., senior research scientist at the Barnett Institute at Northeastern University, relies on PCT for glycan analysis. Glycans are ordinarily N-linked and are evaluated using capillary electrophoresis and liquid chromatography. Dr. Szabo and his colleagues, however, used PCT to accelerate N-linked glycan release by peptides using the enzyme N-Glycosidase F, also known as PNGase F.

Membrane proteins represent one of the most appealing targets for cancer detection and therapy. But the extraction of proteins from membranes is complex and challenging, given the inculcation of the proteins throughout a tenacious lipid bilayer. For this reason, Luke Schneider, Ph.D., CSO, Target Discovery, and his co-workers have applied PCT to the extraction of membrane proteins from ovarian cancer tissues.


'/>"/>

Contact: John Sterling
jsterling@genengnews.com
914-740-2196
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Page: 1

Related biology news :

1. BIO-key® Reports Strong 2010 Second Quarter and Six Month Financial Results
2. International Drug & Explosives Detection Company IDenta Corp Reports on BTK- Bullet Hole Testing Kit
3. Cell Transplantation reports consistent and successful islet isolations offer diabetes hope
4. New climate change reports underscore need for action
5. BIO-key(R) Reports First Quarter 2010 Financial Results
6. Survey reports latest honey bee losses
7. Grupo Radio Centro Reports First Quarter 2010 Results
8. Primary Energy Reports Improved First Quarter Results
9. GEN reports on the promise of DNA vaccines
10. Peregrine reports new study from Duke shows anti-HIV potential of targeting PS on cells
11. NIH stem cell guidelines should be modified, UCSF team reports
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
GEN reports on rediscovered technology to bolster proteomics research
(Date:4/11/2017)... -- Research and Markets has announced the addition of ... offering. ... market to grow at a CAGR of 30.37% during the period ... has been prepared based on an in-depth market analysis with inputs ... growth prospects over the coming years. The report also includes a ...
(Date:4/6/2017)... 6, 2017 Forecasts by Product ... Readers, by End-Use (Transportation & Logistics, Government & Public ... & Fossil Generation Facility, Nuclear Power), Industrial, Retail, Business ... Are you looking for a definitive report on ... ...
(Date:4/5/2017)... KEY FINDINGS The global market ... CAGR of 25.76% during the forecast period of 2017-2025. ... for the growth of the stem cell market. ... MARKET INSIGHTS The global stem cell market is segmented ... The stem cell market of the product is segmented ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... , ... October 12, 2017 , ... ... with the pharmaceutical and biotechnology industries to improve patient outcomes and quality of ... trends in analytical testing are being attributed to new regulatory requirements for all ...
(Date:10/11/2017)... ... 11, 2017 , ... ComplianceOnline’s Medical Device Summit is back for its 4th ... in San Francisco, CA. The Summit brings together current and former FDA office bearers, ... and government officials from around the world to address key issues in device compliance, ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... and pregnancy rates in frozen and fresh in vitro fertilization (IVF) ... maternal age to IVF success. , After comparing the results from the fresh ...
(Date:10/10/2017)... Poway, California (PRWEB) , ... October 10, 2017 , ... ... afternoon speaking at his local San Diego Rotary Club. The event ... San Diego, CA and had 300+ attendees. Dr. Harman, DVM, MPVM was joined ...
Breaking Biology Technology: