Navigation Links
GEN reports on rediscovered technology to bolster proteomics research
Date:8/13/2010

New Rochelle, NY, August 13, 2010Scientists are turning to a decades-old technique to better understand the physical effects of compression on macromolecules and how it might impact their research in proteomics, mass spectrometry, protein extraction, and tissue investigations, reports Genetic Engineering & Biotechnology News (GEN). These studies are built upon the early ultrahigh pressure discoveries of the late Nobel Prize winner in Physics, Percy Bridgman, Ph.D., who was a professor at Harvard from 1908 to 1954, according to the August issue of GEN (http://www.genengnews.com/gen-articles/use-of-ultrahigh-pressure-on-the-rise/3360).

"Pressure-cycling technology (PCT) has definitely caught the attention of an increasing number of scientists," says John Sterling, Editor in Chief of GEN. "In addition, researchers no longer need to construct their own tools because instruments such as the Barocycler from Pressure Biosciences are now available."

Zoltan Szabo, Ph.D., senior research scientist at the Barnett Institute at Northeastern University, relies on PCT for glycan analysis. Glycans are ordinarily N-linked and are evaluated using capillary electrophoresis and liquid chromatography. Dr. Szabo and his colleagues, however, used PCT to accelerate N-linked glycan release by peptides using the enzyme N-Glycosidase F, also known as PNGase F.

Membrane proteins represent one of the most appealing targets for cancer detection and therapy. But the extraction of proteins from membranes is complex and challenging, given the inculcation of the proteins throughout a tenacious lipid bilayer. For this reason, Luke Schneider, Ph.D., CSO, Target Discovery, and his co-workers have applied PCT to the extraction of membrane proteins from ovarian cancer tissues.


'/>"/>

Contact: John Sterling
jsterling@genengnews.com
914-740-2196
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Page: 1

Related biology news :

1. BIO-key® Reports Strong 2010 Second Quarter and Six Month Financial Results
2. International Drug & Explosives Detection Company IDenta Corp Reports on BTK- Bullet Hole Testing Kit
3. Cell Transplantation reports consistent and successful islet isolations offer diabetes hope
4. New climate change reports underscore need for action
5. BIO-key(R) Reports First Quarter 2010 Financial Results
6. Survey reports latest honey bee losses
7. Grupo Radio Centro Reports First Quarter 2010 Results
8. Primary Energy Reports Improved First Quarter Results
9. GEN reports on the promise of DNA vaccines
10. Peregrine reports new study from Duke shows anti-HIV potential of targeting PS on cells
11. NIH stem cell guidelines should be modified, UCSF team reports
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
GEN reports on rediscovered technology to bolster proteomics research
(Date:4/3/2017)... April 3, 2017  Data captured by ... platform, detected a statistically significant association between ... to treatment and objective response of cancer ... to predict whether cancer patients will respond ... as well as to improve both pre-infusion potency ...
(Date:3/29/2017)... March 29, 2017  higi, the health IT company ... North America , today announced a Series ... acquisition of EveryMove. The new investment and acquisition accelerates ... tools to transform population health activities through the collection ... higi collects and secures data today on ...
(Date:3/24/2017)... -- Research and Markets has announced the addition of ... - Industry Forecast to 2025" report to their offering. ... The Global Biometric Vehicle ... around 15.1% over the next decade to reach approximately $1,580 million ... estimates and forecasts for all the given segments on global as ...
Breaking Biology News(10 mins):
(Date:4/26/2017)... ... April 26, 2017 , ... WonderWorks, ... NASA to showcase the future of deep space exploration and inspire space enthusiasts. ... Orion spacecraft and includes a guest appearance by former Shuttle Astronaut Don Thomas. ...
(Date:4/26/2017)... (PRWEB) , ... April 26, 2017 , ... ... headlines and drive high-level conversations among healthcare industry stakeholders, the discussion surrounding the ... – taking place May 15-18, 2017 in Los Angeles, Calif. Hosted by the ...
(Date:4/25/2017)... April 25, 2017 Providence ... licensed its novel immune-modulating technology to an undisclosed global ... allergy. Tregitopes, pronounced T·rej·itopes, are a ... by EpiVax CEO Annie De Groot ... immunoglobulin G, an autoimmune disease therapy, Tregitopes are ...
(Date:4/24/2017)... NEW YORK , April 24, 2017  Dante Labs ... interpretation at only EUR 850 (ca. $900). While American individuals ... marks the first time Europeans can access WGS below EUR ... which are crucial to leveraging genetic information to make informed ... more. ...
Breaking Biology Technology: