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Fungus responsible for 5 deaths in the wake of massive tornado
Date:12/14/2012

e timely diagnosis of mucormycosis is essential for guiding therapy, because the early initiation of appropriate anti-fungal medication and aggressive surgical debridement are associated with improved outcomes."

Both the NEJM and PLOS One studies said whole genome sequencing could lead to better diagnosis and a better understanding of this pathogen.

TGen's DNA sequencing identified Apophysomyces in all 13 of the Joplin cases. The DNA analysis also established that several strains of Apophysomyces were involved in the outbreak, giving scientists further clues that this fungus was well established in the area, and probably had been so for a long time.

"These disasters put us at risk for exposure to organisms that are around us, but don't normally cause disease," Engelthaler said. "There's clearly an entire world out there that we're not seeing on a regular basis. It takes a severe event like this tornado for us to come face-to-face with some of the more dangerous pathogens out there."


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Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

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