Navigation Links
Fully dissolvable, temporary stent for opening heart artery blockages
Date:9/17/2013

The Mount Sinai Medical Center is participating in the nationwide ABSORB III clinical trial testing the performance and potential clinical benefits of a fully dissolvable and temporary drug eluting stent to open heart artery blockages. The randomized trial aims to compare the efficiency and safety of Absorb Bioresorbable Vascular Scaffolds (Absorb BVS) in coronary artery disease patients and compare it to the current standard of care drug eluting metal stents.

Absorb BVS is a flexible artery support tube made of a naturally dissolvable material called polylactide. It is inserted by interventional cardiologists minimally invasively during a cardiac catheterization procedure. Absorb BVS works to line the interior of a blocked heart artery to keep it open and restore proper blood flow to the heart. The supportive tube then dissolves into the artery wall within two years.

"Dissolvable stents may be a future game-changer for the way we treat coronary artery disease and heart attack in the United States if proven to show clinical benefit in this nationwide clinical trial," says Samin K. Sharma, MD, Director of Clinical and Interventional Cardiology at The Mount Sinai Medical Center and the Zena and Michael A. Wiener Professor of Medicine at Icahn School of Medicine at Mount Sinai. "The stent is designed to open a blocked heart vessel and eventually dissolve and disappear, leaving no remnants on the heart of a cardiac interventional procedure."

"We look forward to testing this innovative absorbable artery support technology's efficiency and safety at Mount Sinai," says Annapoorna S. Kini, MD, Director of the Cardiac Catheterization Laboratory at The Mount Sinai Medical Center. "Since the stent is designed to completely dissolve into the arterial tissue it may potentially help improve the overall health of a patient's once blocked heart vessel while restoring its natural flexibility and movement."

"Heart disease is still the number one killer of Americans. This is why we need to study in clinical trial every available therapeutic option for our heart patients to improve their overall heart health and prevent future deadly heart attacks," says Roxana Mehran, MD, Director of Interventional Cardiovascular Research and Clinical Trials at Icahn School of Medicine at Mount Sinai. "It is critical that advances in cardiac interventional technology, currently being used on other continents to help unblock arteries, be tested in clinical trial in the U.S."

The randomized ABSORB III clinical trial plans to enroll approximately 2,250 coronary artery disease patients across the country. Mount Sinai hopes to enroll 50 patients.

Recently, Absorb BVS became commercially available in Europe, India, and parts of Latin America and Asia. So far, more than 1,000 patients around the world have been treated with the device. Absorb BVS is made by the global healthcare company Abbott.


'/>"/>

Contact: Lauren Woods
lauren.woods@mountsinai.org
212-241-2836
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

Related biology news :

1. How to learn successfully even under stress
2. New beautifully colored long-horned beetle from Yunnan, China
3. Chinese scientists successfully crack the genome of diploid cotton
4. Efforts to develop new drugs that hopefully will never be used
5. Scale-up of a temporary bioartificial liver support system described in BioResearch Open Access
6. Temporary storage for electrons: Natural method of producing hydrogen
7. New compound excels at killing persistent and drug-resistant tuberculosis
8. Stenting dramatically improves treatment access for dialysis patients
9. Drug-coated stents prevent leg amputation
10. Stenting blocked bowel arteries saves lives
11. Global nitrogen availability consistent for past 500 years, linked to carbon levels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/22/2016)... 2016 On Monday, the Department of Homeland ... share solutions for the Biometric Exit Program. The Request ... Protection (CBP), explains that CBP intends to add biometrics ... the United States , in order to deter ... Logo - http://photos.prnewswire.com/prnh/20160622/382209LOGO ...
(Date:6/20/2016)... June 20, 2016 Securus Technologies, a ... solutions for public safety, investigation, corrections and monitoring ... involved, it has secured the final acceptance by ... for Managed Access Systems (MAS) installed. Furthermore, Securus ... to be installed by October, 2016. MAS distinguishes ...
(Date:6/15/2016)... , June 15, 2016 ... report titled "Gesture Recognition Market by Application Market - Global Industry ... - 2024". According to the report, the  global gesture ... in 2015 and is estimated to grow at ... billion by 2024.  Increasing application of ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... June 23, 2016 A person commits a crime, ... scene to track the criminal down. An outbreak ... and Drug Administration (FDA) uses DNA evidence to track down ... Sound far-fetched? It,s not. The FDA has increasingly used ... investigations of foodborne illnesses. Put as simply as possible, whole ...
(Date:6/23/2016)... SANTA MONICA, Calif. , June 23, 2016  The Prostate Cancer ... to pioneer increasingly precise treatments and faster cures for prostate cancer. Members of ... 77 institutions across 15 countries. Read More About the ... ... ...
(Date:6/23/2016)... , ... June 23, 2016 , ... ... announced the launch of the Supplyframe Design Lab . Located in Pasadena, ... explore the future of how hardware projects are designed, built and brought to ...
(Date:6/23/2016)... 23, 2016 Apellis Pharmaceuticals, Inc. today ... trials of its complement C3 inhibitor, APL-2. The ... ascending dose studies designed to assess the safety, ... injection in healthy adult volunteers. Forty ... a single dose (ranging from 45 to 1,440mg) ...
Breaking Biology Technology: