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Fruits, vegetables and teas may protect smokers from lung cancer, UCLA researchers report
Date:5/29/2008

g said. We really need to have several larger studies with similar results to confirm our finding. However, its not a bad idea for everyone to eat more fruits and vegetables and drink more tea.

Zhang said flavonoids protect against lung cancer by blocking the formation of blood vessels that tumors develop so they can grow and spread, a process called angiogenesis. They also stop cancer cells from growing, allowing for naturally programmed cell death, or apoptosis, to occur.

The antioxidant properties found in the flavonoids also may work to counteract the DNA damaging effects of tobacco smoking, Zhang said, explaining why they affected the development of lung cancer in smokers but not in non-smokers.

The naturally occurring chemicals may be working to reduce the damage caused by smoking, Zhang said.

The next step, Zhang said, are laboratory-based studies of flavonoids on cell lines and animal models to determine how they are protecting smokers from developing lung cancer. And in addition to larger studies to confirm these findings, other studies need to be done to see if the protective effects of flavonoids extend to other smoking-related cancers, such as bladder, head and neck and kidney cancers.

Zhang and his team also plan to study which types of fruits and vegetables have the highest levels of the flavonoids found to be helpful in this study and what the optimal number of servings per day might be to provide the greatest protection.


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Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
Source:Eurekalert

Page: 1 2

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