Navigation Links
Fruit fly immunity fails with fungus after (space)flight
Date:7/3/2014

d advances our knowledge about these same processes that lead to amazing breakthroughs and discoveries."

Drosophila melanogaster - the common fruit fly - was used in this study, due to its similar human immune function qualities, sharing characteristics of cellular and humoral, or extracellular fluids, immunity and signaling pathways. The fruit fly makes such a great model, in fact, that NASA developed a new Fruit Fly Lab in 2014 to accommodate continued study of Drosophila. This facility will support longer duration studies involving multiple generations of fruit flies.

Kimbrell was one of the earliest investigators into Drosophila immunity. As senior researcher in the Department of Molecular and Cellular Biology at UC Davis, she brought Drosophila immunity into space exploration-related studies. Though fruit fly immunity had been studied on Earth, its immunity had not been studied using hypergravity or spaceflight. Kimbrell and her team of researchers wanted to test the immune response of fruit flies impacted by changes in gravity at the organismal level.

"Immune response is central to health for essentially all organisms, and, not surprisingly, in the stressful space environment there are a variety of changes to how a person or other organisms can fight an infection," explained Kimbrell. "In order to try and understand those changes, my group used the simple fruit fly, well-studied for its immune response on Earth, as a model to help sort out at a cell-based level what happens to the immune response when an organism is in space."

There are two main signaling pathways, Toll and Imd, which act as the go-betweens of immune response to fungal and bacterial infections in fruit flies. In humans, Toll counterparts are known as Toll-like receptors (TLRs), since a 2011 Nobel Prize-winning team discovered the Toll pathway response to immunity first in fruit flies. Humans and other mammals share these two
'/>"/>

Contact: Laura Niles
Laura.E.Niles@nasa.gov
281-244-7069
NASA/Johnson Space Center
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Newly identified gene provides reliable visual cue for oil palm fruit ripeness
2. Fruit flies help scientists uncover genes responsible for human communication
3. Fruit fly research to provide new insight into our body clock and its biological impact
4. Nine young scientists awarded by the Genetics Society of America for fruit fly research
5. Shorter lives for male fruit flies forced to compete
6. Lots of fruits and vegetables, but lots of high-fat snacks
7. Researchers show fruit flies have latent bioluminescence
8. Research from CHORI scientists demonstrates first genome methylation in fruit fly
9. Stink bug traps may increase damage to tomato fruits
10. What singing fruit flies can tell us about quick decisions
11. Study of complete RNA collection of fruit fly uncovers unprecedented complexity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Fruit fly immunity fails with fungus after (space)flight
(Date:7/9/2015)... DUBLIN , July 07, 2015 ... has announced the addition of the "Biometrics ... and Forecasts 2015-2020" report to their offering. ... a major contributor to this growth and the ... US$5.5 billion in revenue for companies involved in ...
(Date:7/8/2015)... 2015 Summary Pancreatic cancer is the ... fatal, with a mortality rate of 10.9 deaths per ... cancer patients has highlighted a significant need for new ... met by the current market. A highly active ... varying molecule types and mechanisms of action, which provides ...
(Date:7/8/2015)... 2015 The consumer products industry for ... have products such as wearables, smart wallets & other smart ... based devices continues to rapidly grow.  Biometrics & Wearable Device ... ), Google Inc. (NASDAQ: GOOG ), Apple Inc. (NASDAQ: ... Inc. (NASDAQ: GPRO ) and Baidu Inc. (NASDAQ: ...
Breaking Biology News(10 mins):Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 2Global Banking Biometrics Market 2015-2020 - Market & Technology Analysis, Adoption Strategies and Forecasts 3Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 2Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 3Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 2Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 3Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 4Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 5Consumers Flock to This Summer's Must Have Tech Gadgets as Latest Digital Wallets, Smart Technology & Wearable Products Continue to Grow in Popularity & Functionality 6
... Case Western Reserve University is part of a landmark ... which are associated with blood pressure. The 19-site meta-analysis, ... of genetic mutations are also associated with blood pressure ... Xiaofeng Zhu, PhD, is co-senior author of the paper, ...
... nearly a hundred thousand years has been found in ... The possibility that extreme life forms might exist in ... Antarctic ice sheet has fascinated scientists for decades. , ... of Antarctica continues to present major technological challenges. ...
... 62nd Annual Meeting of the American Society of Tropical ... medicine experts, will focus on research advances in the ... Africa and Asia, dengue in Central Florida, animal-borne diseases ... Researchers will present: new innovations to combat the global ...
Cached Biology News:African-American study identifies 4 genetic variants associated with blood pressure 2Life found in the sediments of an Antarctic subglacial lake for the first time 2American Society of Tropical Medicine and Hygiene 62nd Annual Meeting Nov. 13-17, Washington DC 2American Society of Tropical Medicine and Hygiene 62nd Annual Meeting Nov. 13-17, Washington DC 3
(Date:7/29/2015)... US-Australian drug discovery company, Novogen Limited (ASX: NRT; NASDAQ: ... progressing its ground-breaking technology platforms to Phase 1 clinical ... Company delivers the best value for shareholders. ... the Company currently had an extensive program of activities ... academic partnerships and initiatives, and he was working with ...
(Date:7/29/2015)... Ala., July 29, 2015  HealthSouth ... nation,s largest providers of post-acute healthcare services, offering ... its results of operations for the second quarter ... quarter was characterized by strong volume growth in ... Adjusted EBITDA," said Jay Grinney, President and Chief ...
(Date:7/29/2015)... , July 29, 2015 ... has announced the addition of the "Global ... their offering. The Global Biosimilars Market, ... of the rapidly growing biosimilars market. With the ... striving to minimize costs, biosimilars are being viewed ...
(Date:7/29/2015)... , July 29, 2015  Therapath Neuropathology ( ... increased partnerships with VA and Military Medical centers ... Fiber Density (ENFD) and Sweat Gland Nerve Fiber ... neuropathy ( https://therapath.com/skin ). Demonstration ... Density (ENFD) on punch skin biopsy is a ...
Breaking Biology Technology:Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 3Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 4Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 5Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 6Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 7Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 8Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 9Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 10HealthSouth Reports Results for Second Quarter 2015 2HealthSouth Reports Results for Second Quarter 2015 3HealthSouth Reports Results for Second Quarter 2015 4HealthSouth Reports Results for Second Quarter 2015 5HealthSouth Reports Results for Second Quarter 2015 6HealthSouth Reports Results for Second Quarter 2015 7HealthSouth Reports Results for Second Quarter 2015 8HealthSouth Reports Results for Second Quarter 2015 9HealthSouth Reports Results for Second Quarter 2015 10HealthSouth Reports Results for Second Quarter 2015 11HealthSouth Reports Results for Second Quarter 2015 12HealthSouth Reports Results for Second Quarter 2015 13HealthSouth Reports Results for Second Quarter 2015 14HealthSouth Reports Results for Second Quarter 2015 15HealthSouth Reports Results for Second Quarter 2015 16HealthSouth Reports Results for Second Quarter 2015 17HealthSouth Reports Results for Second Quarter 2015 18HealthSouth Reports Results for Second Quarter 2015 19HealthSouth Reports Results for Second Quarter 2015 20HealthSouth Reports Results for Second Quarter 2015 21HealthSouth Reports Results for Second Quarter 2015 22HealthSouth Reports Results for Second Quarter 2015 23HealthSouth Reports Results for Second Quarter 2015 24HealthSouth Reports Results for Second Quarter 2015 25HealthSouth Reports Results for Second Quarter 2015 26HealthSouth Reports Results for Second Quarter 2015 27
... 2008, 5:00 ... EDT, FRAZER, Pa., March 31 Cephalon, Inc.,(Nasdaq: CEPH ) has scheduled its ... 1,2008., ... 4:10 p.m. EDT Q1 2008 results will be distributed by PRNewswire 4:50 ...
... year Revenue Increased 51.9% to $33.2 Million, ... Income Increased 49.3% to $12.8 Million, ... Revenue for 2008 NEW YORK and HAIKOU, Hainan, ... (OTC Bulletin Board: CPHI) which develops, manufactures, and,markets generic ...
... BioMarin,Pharmaceutical Inc. (Nasdaq and SWX: BMRN) announced ... distribution partner in Japan, has,received approval for its ... of Health, Labour and Welfare,(MHLW) for the treatment ... "We are proud to work with AnGes in ...
Cached Biology Technology:China Pharma Holdings, Inc. Announces Record 2007 Year End Results 2China Pharma Holdings, Inc. Announces Record 2007 Year End Results 3China Pharma Holdings, Inc. Announces Record 2007 Year End Results 4China Pharma Holdings, Inc. Announces Record 2007 Year End Results 5China Pharma Holdings, Inc. Announces Record 2007 Year End Results 6China Pharma Holdings, Inc. Announces Record 2007 Year End Results 7China Pharma Holdings, Inc. Announces Record 2007 Year End Results 8China Pharma Holdings, Inc. Announces Record 2007 Year End Results 9China Pharma Holdings, Inc. Announces Record 2007 Year End Results 10China Pharma Holdings, Inc. Announces Record 2007 Year End Results 11Naglazyme Approved by Japanese Ministry of Health 2Naglazyme Approved by Japanese Ministry of Health 3Naglazyme Approved by Japanese Ministry of Health 4
Dual-bay Dyad thermal cycler chassis, does not include the Alpha units (requires 2)...
Artisan™ Wash Solution (x 50) Additional Information: EU regulatory status: CE US regulatory status: IVD ...
... Immunophosphatase Secondary Detection System is intended for ... Primary Antibody reagents, which contain rat and ... antigens by light microscopy in paraffin-embedded tissues. ... may also be used with other rat ...
... Lower operational costs. More efficient interfacing ... limited sample volumes. Industry demands for ... using microbore chromatography for routine applications. ... adequately satisfy the need to operate ...
Biology Products: