Navigation Links
Fruit fly immunity fails with fungus after (space)flight
Date:7/3/2014

d advances our knowledge about these same processes that lead to amazing breakthroughs and discoveries."

Drosophila melanogaster - the common fruit fly - was used in this study, due to its similar human immune function qualities, sharing characteristics of cellular and humoral, or extracellular fluids, immunity and signaling pathways. The fruit fly makes such a great model, in fact, that NASA developed a new Fruit Fly Lab in 2014 to accommodate continued study of Drosophila. This facility will support longer duration studies involving multiple generations of fruit flies.

Kimbrell was one of the earliest investigators into Drosophila immunity. As senior researcher in the Department of Molecular and Cellular Biology at UC Davis, she brought Drosophila immunity into space exploration-related studies. Though fruit fly immunity had been studied on Earth, its immunity had not been studied using hypergravity or spaceflight. Kimbrell and her team of researchers wanted to test the immune response of fruit flies impacted by changes in gravity at the organismal level.

"Immune response is central to health for essentially all organisms, and, not surprisingly, in the stressful space environment there are a variety of changes to how a person or other organisms can fight an infection," explained Kimbrell. "In order to try and understand those changes, my group used the simple fruit fly, well-studied for its immune response on Earth, as a model to help sort out at a cell-based level what happens to the immune response when an organism is in space."

There are two main signaling pathways, Toll and Imd, which act as the go-betweens of immune response to fungal and bacterial infections in fruit flies. In humans, Toll counterparts are known as Toll-like receptors (TLRs), since a 2011 Nobel Prize-winning team discovered the Toll pathway response to immunity first in fruit flies. Humans and other mammals share these two
'/>"/>

Contact: Laura Niles
Laura.E.Niles@nasa.gov
281-244-7069
NASA/Johnson Space Center
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Newly identified gene provides reliable visual cue for oil palm fruit ripeness
2. Fruit flies help scientists uncover genes responsible for human communication
3. Fruit fly research to provide new insight into our body clock and its biological impact
4. Nine young scientists awarded by the Genetics Society of America for fruit fly research
5. Shorter lives for male fruit flies forced to compete
6. Lots of fruits and vegetables, but lots of high-fat snacks
7. Researchers show fruit flies have latent bioluminescence
8. Research from CHORI scientists demonstrates first genome methylation in fruit fly
9. Stink bug traps may increase damage to tomato fruits
10. What singing fruit flies can tell us about quick decisions
11. Study of complete RNA collection of fruit fly uncovers unprecedented complexity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Fruit fly immunity fails with fungus after (space)flight
(Date:4/2/2015)... 2, 2015 In the ... far outperforms the strongest competitors, showing outstanding performance ... the system is capable of a throughput of ... up to be ten times faster than most ... performance.      (Photo: http://photos.prnewswire.com/prnh/20150402/738673-a ...
(Date:4/1/2015)... , April 1, 2015   Medisafe ™, ... million users across iOS and Android ... begun integrating biofeedback into the platform to allow patients ... outcomes. For the first time, patients will be able ... a dose impacts important biometrics, such as glucose levels ...
(Date:3/24/2015)... Mar. 24, 2015 Research and Markets ... "Global Iris Recognition Market 2015-2019" report to ... Iris Recognition market to grow at a CAGR of ... report covers the present scenario and the growth prospects ... 2015-2019. To calculate the market size, the report considers ...
Breaking Biology News(10 mins):DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 2DERMALOG AFIS Emerges as Performance Winner in NIST Benchmark Test 3Medisafe Announces Launch of Biometric Integration, Enabling Patients to Stay Adherent to Their Meds and See Tangible Health Results 2Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2
... have discovered how two closely related proteins guide projections ... repelling these axons as they navigate the most miniscule ... remarkably precise connections. The discovery, reported April 28 ... belonging to the "semaphorin" family of guidance cues are ...
... As part of the Genome Canada Large-Scale Applied Research ... million to 16 projects across the country, the researchers ... function with the aim of identifying genes or proteins ... to target cancers and other diseases. The first ...
... by a parasitic fungus dramatically changes the behavior of tropical ... to become zombie-like and to die at a spot that ... team studied ants living high up in the rainforest canopy ... in the BioMed Central open-access journal BMC Ecology ...
Cached Biology News:Johns Hopkins scientists reveal nerve cells' navigation system 2Johns Hopkins scientists reveal nerve cells' navigation system 3OGI genomics researchers awarded $23 million 2OGI genomics researchers awarded $23 million 3Zombie ants have fungus on the brain, new research reveals 2
(Date:4/23/2015)... CA (PRWEB) April 23, 2015 Delpor, ... today announced that the United States Patent and Trademark ... Company’s NANOPOR™ technology. US Pat. No. ... Delpor’s microfabricated drug delivery device for the ... proprietary NANOPOR™ technology for the sustained (zero-order) release of ...
(Date:4/22/2015)... , April 22, 2015 /PRNewswire/ - BioAmber Inc. (NYSE and EURONEXT Paris:BIOA) today ... first quarter 2015 on Thursday, May 7, 2015 after ... a webcast and conference call for 4.30 pm ET ... Live audio of the conference call will be ... investors, members of the news media and the general ...
(Date:4/22/2015)... Calif. , April 22, 2015 ... and analytics, announced today that it has opened ... its continued growth and expansion.  The common stock ... Act, Section 506(c), a law intended to encourage ... regulations.  Prior to 506(c), small businesses largely relied ...
(Date:4/22/2015)... 2015 /PRNewswire/ - Portage Biotech Inc. ("Portage") (OTC Market: ... announce that Biohaven Pharmaceutical Holding Company Limited (Biohaven), ... to initiate a Phase 1 pharmacokinetic and biomarker ... Biohaven plans to initiate the trial no later ... in the Phase 1 study, Biohaven will move ...
Breaking Biology Technology:Delpor, Inc. Announces the Issuance of 2 New US Patents Based on its Nanopore Technology which Enables the Sustained Release of Drugs from a Small Implant Device 2Delpor, Inc. Announces the Issuance of 2 New US Patents Based on its Nanopore Technology which Enables the Sustained Release of Drugs from a Small Implant Device 3BioAmber Announces Webcast of Fiscal First Quarter 2015 Financial Results 2Steep Hill Launches $5M Limited Stock Offering 2Steep Hill Launches $5M Limited Stock Offering 3Portage's Biohaven to begin Phase 1 study in 3Q2015 and readying for Phase 3 study start by 1Q2016 2Portage's Biohaven to begin Phase 1 study in 3Q2015 and readying for Phase 3 study start by 1Q2016 3
... , , , , ... Inc.,(Nasdaq: SSRX ), a leading biotechnology company focused ... today announced that it has submitted its application for ... Drug,Administration ("SFDA") for Feraheme (ferumoxytol) Injection for intravenous,use. Feraheme ...
... , , ... enrollment of patients with acute ischemic stroke into its,Phase III ... at the Wolfson Medical Center, Israel. The MACSI trial involves,numerous ... Korea and Brazil. DP-b99 is D-Pharm,s most advanced product developed,for ...
... WASHINGTON, Dec. 29 The National Fragile X Foundation applauds ... Fragile X Syndrome for the first time ever within a ... U.S. Department of Defense. , The new law, ... through the FY 2010 Department of Defense Appropriations Act for ...
Cached Biology Technology:3SBio Inc. Applies for SFDA Registrational Trial for Feraheme(TM) 23SBio Inc. Applies for SFDA Registrational Trial for Feraheme(TM) 33SBio Inc. Applies for SFDA Registrational Trial for Feraheme(TM) 4D-Pharm (TASE: DPRM) Announces Enrollment of First Patient in DP-b99 Phase III Efficacy Study, MACSI 2D-Pharm (TASE: DPRM) Announces Enrollment of First Patient in DP-b99 Phase III Efficacy Study, MACSI 3Defense Department to Support Fragile X Research 2