Navigation Links
Fruit fly immunity fails with fungus after (space)flight
Date:7/3/2014

d advances our knowledge about these same processes that lead to amazing breakthroughs and discoveries."

Drosophila melanogaster - the common fruit fly - was used in this study, due to its similar human immune function qualities, sharing characteristics of cellular and humoral, or extracellular fluids, immunity and signaling pathways. The fruit fly makes such a great model, in fact, that NASA developed a new Fruit Fly Lab in 2014 to accommodate continued study of Drosophila. This facility will support longer duration studies involving multiple generations of fruit flies.

Kimbrell was one of the earliest investigators into Drosophila immunity. As senior researcher in the Department of Molecular and Cellular Biology at UC Davis, she brought Drosophila immunity into space exploration-related studies. Though fruit fly immunity had been studied on Earth, its immunity had not been studied using hypergravity or spaceflight. Kimbrell and her team of researchers wanted to test the immune response of fruit flies impacted by changes in gravity at the organismal level.

"Immune response is central to health for essentially all organisms, and, not surprisingly, in the stressful space environment there are a variety of changes to how a person or other organisms can fight an infection," explained Kimbrell. "In order to try and understand those changes, my group used the simple fruit fly, well-studied for its immune response on Earth, as a model to help sort out at a cell-based level what happens to the immune response when an organism is in space."

There are two main signaling pathways, Toll and Imd, which act as the go-betweens of immune response to fungal and bacterial infections in fruit flies. In humans, Toll counterparts are known as Toll-like receptors (TLRs), since a 2011 Nobel Prize-winning team discovered the Toll pathway response to immunity first in fruit flies. Humans and other mammals share these two
'/>"/>

Contact: Laura Niles
Laura.E.Niles@nasa.gov
281-244-7069
NASA/Johnson Space Center
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Newly identified gene provides reliable visual cue for oil palm fruit ripeness
2. Fruit flies help scientists uncover genes responsible for human communication
3. Fruit fly research to provide new insight into our body clock and its biological impact
4. Nine young scientists awarded by the Genetics Society of America for fruit fly research
5. Shorter lives for male fruit flies forced to compete
6. Lots of fruits and vegetables, but lots of high-fat snacks
7. Researchers show fruit flies have latent bioluminescence
8. Research from CHORI scientists demonstrates first genome methylation in fruit fly
9. Stink bug traps may increase damage to tomato fruits
10. What singing fruit flies can tell us about quick decisions
11. Study of complete RNA collection of fruit fly uncovers unprecedented complexity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Fruit fly immunity fails with fungus after (space)flight
(Date:7/31/2014)... exposure to loud noise alters how the brain ... speech sounds, according to neuroscientists at The University ... published this week in Ear and Hearing ... noise-induced hearing loss affects the brain,s recognition of ... all corners of the population, affecting an estimated ...
(Date:7/31/2014)... week that the U.S. surgeon general issued a 101-page ... Montana State University published a paper breaking new ground ... cell responds when exposed to ultraviolet (UV) light. ... by the UV rays found in sunlight. This damage ... eye diseases. , "Our paper advances foundational knowledge ...
(Date:7/31/2014)... are familiar with Hibiscus flowers- they are an ... are commonly planted in the landscape. Some, like ... endangered species. , Only a relatively few botanists ... an equally beautiful and intriguing related group of ... of Hibiscus". , Brother of Hibiscus species are ...
Breaking Biology News(10 mins):UT Dallas study reveals effect of loud noises on brain 2New paper describes how DNA avoids damage from UV light 2New paper describes how DNA avoids damage from UV light 3Brother of Hibiscus is found alive and well on Maui 2
... esparto fields from Guadalajara to Murcia and has concluded ... system against desertification in these ecosystems. The study has ... In order to foresee the appearance of ... "degradation of the land into arid, semi-arid and sub-humid ...
... In a biological rendition of fiction,s Strange Case of ... campus in Florida and Harvard Medical School have found that ... spur the spread of tumors. The scientists, reporting ... Biology , found that FOXO3a, a transcription factor that regulates ...
... science, and scientists need an informed, thoughtful, and open-minded ... science is strikingly inconsistent with the low level of ... as the "Year of Science," professional scientific organizations and ... invigorated focus on the importance of science now and ...
Cached Biology News:Perennial vegetation, an indicator of desertification in Spain 2Perennial vegetation, an indicator of desertification in Spain 3Mayo Clinic researchers find that protein believed to protect against cancer has a Mr. Hyde side 2How to advance scientific literacy 2How to advance scientific literacy 3
(Date:7/31/2014)... at Indiana University Bloomington have described the self-assembly ... development with potential value for the field of ... photovoltaic cells. , Their paper, "Anion-Induced Dimerization of ... 2D Self-Assembled Crystals," has been published online by ... Royal Society of Chemistry. It is the first ...
(Date:7/31/2014)... Graphite Metallizing Corporation announces GRAPHALLOY® bearings ... are uniquely suited to prevent loss of lubrication that ... high temperatures . , Recently, a manufacturer of ... at Graphite Metallizing to overcome problems with movement of ... pans containing blocks of powder mixture are loaded onto ...
(Date:7/31/2014)... CollabRx, Inc. (NASDAQ: CLRX), a leading ... oncology, today announced that it will hold an investor ... Company's financial results for the first quarter of fiscal ... in the current fiscal year. , The dial-in number ... 14, 2014, at 5 p.m. EDT (2 p.m. PDT) ...
(Date:7/31/2014)... Francisco, Calif. (PRWEB) July 31, 2014 ... newly diagnosed patients with an overview of the disease ... management of drug side effects, as well as updates ... “We’re grateful to Dr. Sandy Srinivas for organizing this ... survivor of kidney cancer. “Sandy and her colleagues have ...
Breaking Biology Technology:Chemists demonstrate 'bricks-and-mortar' assembly of new molecular structures 2Chemists demonstrate 'bricks-and-mortar' assembly of new molecular structures 3Graphite Metallizing Announces Bearings for High Temperature Oven Applications 2Graphite Metallizing Announces Bearings for High Temperature Oven Applications 3CollabRx, Inc. Schedules First Quarter Fiscal Year 2015 Financial Conference Call and Business Update 2
... Biodel, Inc. (Nasdaq:,BIOD) today announced the addition ... Directors., Dr. Pereira is the President and ... to the development and,commercialization of therapeutic and diagnostic ... role in advancing the,company,s key product candidate, Ferumoxytol, ...
... Royal,Society of Chemistry today announced the creation of the ... social development of,the continent. The Network, which will eventually ... Its purpose is to connect African,chemists more effectively and ... scientific development., Syngenta is supporting the launch with ...
... CAMBRIDGE, Mass. Breathing new life into an ... and co-workers are developing innovative materials for controlling ... by allowing more efficient car engines, photovoltaic cells ... have already resulted in a new consumer product: ...
Cached Biology Technology:Brian J.G. Pereira, M.D. Joins Biodel's Board of Directors 2Brian J.G. Pereira, M.D. Joins Biodel's Board of Directors 3Brian J.G. Pereira, M.D. Joins Biodel's Board of Directors 4Syngenta and The Royal Society of Chemistry Launch African Science Initiative 2Syngenta and The Royal Society of Chemistry Launch African Science Initiative 3MIT: Thermoelectric materials are 1 key to energy savings 2MIT: Thermoelectric materials are 1 key to energy savings 3
... Many differences exist between the various ... of glass slide used, the length and ... targets, and the manufacturing protocol employed all ... microarray analysis. With all the different ...
... Extraction Software reads and processes ... prepare microarray data for analysis. ... one 2-year license for ... accounts , * one ...
... The DMW143 taken from the SMZ line is ... of production and testing. It is available with ... (FBGG) or a space-saving compact base (N2GG). This ... TV and a projector all at the same ...
... The economical ICS-90 uses continuous chemical suppression ... give you fast, accurate determinations of common ... Easy to operate, quick to equilibrate, and ... compact ICS-90 helps you achieve maximum sample ...
Biology Products: