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Fruit flies help scientists uncover genes responsible for human communication
Date:6/26/2014

COLUMBIA, Mo. The evolution of language in humans continues to perplex scientists and linguists who study how humans learn to communicate. Considered by some as "operant learning," this multi-tiered trait involves many genes and modification of an individual's behavior by trial and error. Toddlers acquire communication skills by babbling until what they utter is rewarded; however, the genes involved in learning language skills are far from completely understood. Now, using a gene identified in fruit flies by a University of Missouri researcher, scientists involved in a global consortium have discovered a crucial component of the origin of language in humans.

"One effective way of uncovering the root of language development is to study language impairment disorders that are genetically-based," said Troy Zars, associate professor of biological sciences in the College of Arts and Science at MU. "By isolating the genes involved, we can uncover the biological basis of human language. In 2007, our team discovered that a gene in the fruit fly genome was very similar to the human version of the Forkhead Box P (FoxP) gene and in our latest study, we have determined it is a major player in behavior-based, or operant, learning."

In 2010, Zars presented his findings at the Dahlem Colloquium Seminar Series supported by the Freie Universitt and the Max Plank Institute for Molecular Genetics in Berlin. There, he met with Bjoern Brembs, professor of neurogenetics at the University of Regensburg; Constance Scharff, professor of biology at the Freie Universitt Berlin; and Juergen Rybak, group leader of evolutionary neuroethology at the Max Plank Institute for Chemical Ecology. They formed a consortium together with Ezekiel Mendoza, Julien Colomb, and Hans-Joachim Pflueger to examine operant learning in fruit flies.

The researchers studied flies in which the FoxP gene had been modified. In a learning experiment that comes as close to simulating human l
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Contact: Jesslyn Chew
ChewJ@missouri.edu
573-882-8353
University of Missouri-Columbia
Source:Eurekalert

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