Navigation Links
Frozen flies may yield secrets for human organ transplants
Date:8/19/2010

CAMDEN When kitchens become infiltrated with fruit flies, especially during the dog days of summer, homeowners might wish that the flying pests would just turn to ice.

The fruit fly Drosophila melanogaster does boast a powerful genetic system making it an ideal organism to test a cool new discovery: how an enzyme regulates body energy levels. Shutting off this molecular thermostat could result in a newfound cold tolerance that has multiple applications, including extending the 24-hour window donated organs now have for optimum use.

Thanks to a $385,419 grant from the National Institute of Health, a team of RutgersCamden biologists is working to engineer cold tolerant fruit flies and ultimately human cells within the next three years.

This research breakthrough can be credited to Daniel Shain, a professor of biology at RutgersCamden, who has traveled the globe seeking knowledge on how ice worms don't just survive in glaciers, but thrive. When Shain identified a key enzyme that helps ice worms do this AMP phosphatase he tapped Nir Yakoby, an expert Drosophila geneticist and assistant professor of biology at RutgersCamden, to create this cold-tolerant fruit fly.

"The goal is to make human cells survive on ice. Twenty-four hours on ice is pushing it and many people die waiting," says Shain, who is scheduled to travel to Tibet next year to observe ice worms in the vicinity. "We're lucky to have an expert Drosophila geneticist on campus to test this genetic switch."

Not just the ice worm lives on ice; the RutgersCamden research team, which includes undergraduate and graduate students, observed how other organisms, like bacteria, fungi, and algae, also are breaking through their internal thermostats.

"Shain accomplished this switch in mono-cell organisms and now we are going further up into the evolutionary tree to a more complex species," offers Yakoby, who joined the RutgersCamden faculty last year a
'/>"/>

Contact: Cathy Donovan
catkarm@camden.rutgers.edu
856-225-6627
Rutgers University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Creation of the first frozen repository for Hawaiian coral
2. Late-surviving megafauna exposed by ancient DNA in frozen soil
3. Frozen assets: NIAID researchers turn to unique resource for clues to norovirus evolution
4. ICSI or IVF: Babies born from frozen embryos do just as well
5. A tiny frozen microbe may hold clues to extraterrestrial life
6. Butterflies shed light on how some species respond to global warming
7. From butterflies wings to bank notes -- how natures colors could cut bank fraud
8. Resistant wheat rebuilds cell walls when attacked by Hessian flies
9. As monarch butterflies journey north, gardeners can help protect species, researcher says
10. Male or female? In flies, some cells cant tell
11. Water may not run uphill, but it practically flies off new surface
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/11/2015)... , June 11, 2015 Daon, ... announced today that its IdentityX Mobile Authentication Platform ... IDentity Online) Alliance is an industry consortium launched ... standards for simpler, stronger authentication.  In order to ... pass a rigorous series of tests that measure ...
(Date:6/9/2015)... , June 9, 2015   MedNet Solutions ... the entire spectrum of clinical research, will be providing ... technology platform at the 2015 Drug Information Association (DIA) ... on June 15-17.  These presentations will include previews of ... out in the upcoming iMedNet 2015 Feature ...
(Date:6/8/2015)... , June 8, 2015  Trovagene, Inc. (NASDAQ: TROV ... clinical data featuring its Precision Cancer Monitoring SM platform ... Liquid Biopsies conference in San Diego, CA ... Precision Medicine Series: Integrating Clinical Genomics and Cancer Therapy ... June 13-16. "We continue to advance our ...
Breaking Biology News(10 mins):Daon's IdentityX Mobile Authentication Platform One of First Products to be Certified by FIDO Alliance 2MedNet To Provide Sneak Peeks Of Its iMedNet "2015 Feature 1 Release" At The DIA Annual Meeting 2MedNet To Provide Sneak Peeks Of Its iMedNet "2015 Feature 1 Release" At The DIA Annual Meeting 3Clinical Data Featuring Trovagene's Urine-Based Liquid Biopsy Platform to be Presented at Two Upcoming Medical Conferences 2Clinical Data Featuring Trovagene's Urine-Based Liquid Biopsy Platform to be Presented at Two Upcoming Medical Conferences 3Clinical Data Featuring Trovagene's Urine-Based Liquid Biopsy Platform to be Presented at Two Upcoming Medical Conferences 4
... populating the growing brain, neural stem cells must strike a ... the cells multiply to provide plenty of starting materials ... If the stem cells proliferate too much, they could ... proliferate too little, there may not be enough cells to ...
... / b3c newswire / - KINAXO Biotechnologies GmbH ... service portfolio. KinAffinity provides invaluable information about a ... of interest. It simultaneously determines affinities for native ... overcomes the limitations of traditional biochemical assays that ...
... of researchers from the University of Maryland Center for ... study to forecast the effects of environmental change on ... by a $620,000 grant from the National Science Foundation, ... Preserve near Alexandria, Virginia. "Freshwater marshes are integral ...
Cached Biology News:UNC study pinpoints gene controlling number of brain cells 2KINAXO launches KinAffinity services for efficient profiling of kinase inhibitors in cells or tissue 2
(Date:7/2/2015)... 2015  Spherix Incorporated (Nasdaq: SPEX ) -- an intellectual ... of intellectual property, today announced a litigation update. ... Verizon Services Corp. et al. , Case No. 1:14-cv-00721-GBL-TCB, ... District of Virginia , the Court ... certain key claims in favor of the Defendants on ...
(Date:7/2/2015)... Memphis, TN (PRWEB) , ... July 02, 2015 ... ... in the development and manufacturing of surgical instruments in Orthopedics, announced today the ... orthopedic contract-manufacturing and the world's largest provider of surgical instruments to the Spine ...
(Date:7/1/2015)... 1, 2015   Decision Resources Group ... of Otezla are its oral administration, alternative mechanism ... by surveyed rheumatologists. Otezla was the first oral ... of active psoriatic arthritis in the ... care includes conventional oral treatments including disease-modifying antirheumatic ...
(Date:7/1/2015)... , July 1, 2015   Neuraltus ... the development of groundbreaking drugs to treat neurodegenerative ... today that Robert G. Miller , M.D., Director ... Sutter Health,s California Pacific Medical Center in San Francisco, ... Association for $1.5 million to help fund a ...
Breaking Biology Technology:Spherix Issues A Litigation Update 2Spherix Issues A Litigation Update 3In'Tech Medical Acquires Turner Medical to Become a World Leader in Orthopedic Contract-Manufacturing 2In'Tech Medical Acquires Turner Medical to Become a World Leader in Orthopedic Contract-Manufacturing 3Surveyed Rheumatologists Report That Otezla's Oral Administration is its Single Greatest Advantage Over Currently Available Treatment Options 2Surveyed Rheumatologists Report That Otezla's Oral Administration is its Single Greatest Advantage Over Currently Available Treatment Options 3Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 2Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 3Investigator to Receive $1.5 Million Grant from the ALS Association to Help Fund Confirmatory Phase 2 Study of Neuraltus Pharmaceuticals' NP001 4
... June 2 Repligen Corporation (Nasdaq: RGEN ) announced today ... year 2010, on Wednesday, June 9th, 2010 , before the market opens. ... will host a conference call and webcast on the same day at ... update on the Company. , , ...
... SHANGHAI , June 2 /PRNewswire-Asia-FirstCall/ -- China-Biotics, Inc.,("China-Biotics", the ... products in China , today announced,it will host a conference call ... 2010 , to discuss the fourth quarter and fiscal year 2010 annual,financial ... , , ...
... SHANGHAI , June 2 /PRNewswire-Asia-FirstCall/ -- China-Biotics, Inc.,("China-Biotics", the ... in China , today announced,that its management will present at the Bank ... Tuesday, June 22, 2010 at the Merrill,Lynch Client Service Center in ... ...
Cached Biology Technology:Repligen Announces Conference Call of Fourth Quarter and Fiscal Year 2010 Financial Results 2Repligen Announces Conference Call of Fourth Quarter and Fiscal Year 2010 Financial Results 3China-Biotics to Report Fourth Quarter and Fiscal Year 2010 Financial Results on June 11 2China-Biotics to Present at Bank of America Merrill Lynch Healthcare Event on June 22 2