Navigation Links
From pre-gut cells to glory
Date:6/3/2011

e genes interacted over time to turn each other on and off.

"The instructions for development have to be in the genome somewhere, but you would be surprised how fragmentary the information about how that works was until we did this system-level analysis," says Davidson. "You can never understand it by looking at one gene. You can never understand it by looking at a third of the genes. You really have to get the whole system mapped outand that's what we did."

In 2008, Davidsonwho has been studying the biological processes of sea urchins for many yearsled a research team that sketched a rough outline, for the first time, of how the GRN works to produce the sea urchin's skeletal system. "We are light-years beyond that with this new study," he says. "That was about solving network subcircuits, but now we have a framework that causally explains the far more complex process of development required for gut formation in terms of the genome's regulatory instruction code." This advance opens a much larger range of developmental scenarios to causal network analysis.

Sea urchins' gene regulatory systems, Davidson points out, are the closestamong the thoroughly studied invertebrate systemsto those of mammals, in terms of evolutionary relationships. This means the mechanisms the team uncovered in their work are likely to illuminate our own developmental regulatory systems. This could have implications for human health.

"If you believe that medicine consists of putting Band-Aids on things, then we have no relevance to that," says Davidson. "But if you believe that we should understand how life works before trying to find a cure when something goes wrong, then understanding biological processes from their initial stages comes first."

The team would next like to take their framework analysis and apply it to later stages in developmentto when the gut is actually present. "We would like to understand how the different compartments in the g
'/>"/>

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. NSF funds new Center for the Physics of Living Cells at Illinois
3. When cells go bad
4. The role of stem cells in renewing the cornea
5. Breast cancer cells recycle to escape death by hormonal therapy
6. Models of eel cells suggest electrifying possibilities
7. Scientists identify a molecule that coordinates the movement of cells
8. Form of Crohns disease traced to disabled gut cells
9. Cold Spring Harbor Laboratory scientists trace a novel way cells are disrupted in cancer
10. Researchers design artificial cells that could power medical implants
11. Stabilizing force for good communication between neurons and muscle cells found
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
From pre-gut cells to glory
(Date:3/24/2015)... , March 24, 2015   NexID Biometrics ... with critical security-authentication needs, today announced the beginning of ... (FFD) solution. The company, based in ... at the three-day Connect:ID Expo, which began here today ... NexID said version 2.0 of its SDK boosts the ...
(Date:3/23/2015)... , March 23, 2015  In the 2014 ... fraud case conviction losses. This figure accounts for a ... according to The Nilson Report, exceeds $11 billion globally. ... tool after a crime has occurred. Investor Mark ... polygraph expert Joe Paolella partnered to administer ...
(Date:3/20/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" ... the growing mobile commerce market, announces its biometric payment ... products featured in 2015 "I Want That" International CES ... on the DIY Network.   DIY,s "I ... , site of the 2015 International CES for a ...
Breaking Biology News(10 mins):NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 2NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 3
... Durham University scientists are to play a key part in ... cultures. Drs Keith Dobney and Greger Larson, ... voyage, which will be the first ever expedition to sail ... which attempts to re-trace the genuine migration route of the ...
... November 6, 2008, Cambridge, UK ,A new study ... system deficits characteristic of multiple sclerosis and other related ... of several diseases in which myelin the insulator ... down and causes severe deficits in brain and nerve ...
... 5, 2008 -- Underwater wi-fi, music over the internet, ... their favorite salmon, detecting dangerous swimmers, helping people who ... sound of musical instruments, and finding a possible way ... These are a few of the topics that will ...
Cached Biology News:6,000km trip to reveal clues to ancient migration 2Multiple sclerosis research charges ahead with new mouse model of disease 2Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 2Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 3Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 4Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 5Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 6Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 7Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 8Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 9Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 10Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 11Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 12Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 13Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 14Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 15Acoustical Meeting, Nov. 10-14, 2008 in Miami, Florida 16
(Date:4/30/2015)... April 30, 2015 Available in ... http://www.lespausa.com , Fleur’s introduces ... combining the benefits of makeup, skin care and ... tinted cream is designed with specific complexion-correcting pigments ... even complexion and a healthy glow. Far more ...
(Date:4/30/2015)... (PRWEB) April 30, 2015 Clinovo ... 2015 PharmaSUG Annual Conference held in Orlando, FL ... Staffing Solutions along with Leslie Kolman, Manager of Staffing ... latest Clinovo news at Booth #17. , “We ... Conference again this year”, Says Trisha Heredia, Senior Director ...
(Date:4/29/2015)... Maryland, USA (PRWEB) April 29, 2015 ... optical sensing, and imaging on the East Coast, reaffirmed ... program managers, researchers, applications developers, and industry suppliers to ... and imaging for multiple applications. , The event included ... and commercial and scientific sensing and imaging -- and ...
(Date:4/29/2015)... 2015 Cambrex Corporation (NYSE: CBM ) announced ... Friday, May 1, 2015 before the market opens. , ... host a conference call to discuss the financial results. First ... , Friday, May 1, 2015 at 8:30 a.m. Eastern ... U.S.1-719-325-2454 for International  Passcode:  7993632 Dial-in Replay: ...
Breaking Biology Technology:Fleur’s Introduces CC CRÈME Perfect Skin Solution 2Fleur’s Introduces CC CRÈME Perfect Skin Solution 3Clinovo Exhibits at the 2015 PharmaSUG Annual Conference on May 17-20th in Orlando, FL 2Clinovo Exhibits at the 2015 PharmaSUG Annual Conference on May 17-20th in Orlando, FL 3SPIE DSS provides venue for collaboration vital to research, applications advances 2SPIE DSS provides venue for collaboration vital to research, applications advances 3SPIE DSS provides venue for collaboration vital to research, applications advances 4
... Aug. 13 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc., (TSX: SDI), ... and a therapeutic targeting severe sepsis, today announced its ... 2009. , "During the quarter, results of the EUPHAS ... American Medical Association (JAMA). The findings showed that the ...
... ... This two part Optimization and Scale-up of a Hydrodynamically Limited ... on an award winning paper presented at the 16th International Process ... for the optimization and scale-up of hydrodynamically limited antisolvent crystallization process. ...
... If manmade devices could be combined with biological ... a boost in operating efficiency. Lawrence Livermore ... platform that uses lipid-coated nanowires to build prototype ... circuits could enhance biosensing and diagnostic tools, advance ...
Cached Biology Technology:Spectral announces second quarter 2009 results 2Spectral announces second quarter 2009 results 3Spectral announces second quarter 2009 results 4Spectral announces second quarter 2009 results 5Spectral announces second quarter 2009 results 6Spectral announces second quarter 2009 results 7Spectral announces second quarter 2009 results 8Optimization and Scale-up of a Hydrodynamically Limited Anti-Solvent Crystallization Process: From Lab to Plant 2Nanoelectronic transistor combined with biological machine could lead to better electronics 2
ELF® 97 Immunohistochemistry Kit...
MOUSE ANTI HUMAN FACTOR I...
GFX PCR DNA,Gel Band Purif,100, 1 EA. Category: Nucleotide Sample Handling....
Superior homology search software - in all the flavours of blast, with increased sensitivity and speed...
Biology Products: