Navigation Links
From pre-gut cells to glory
Date:6/3/2011

Cell Biology at Caltech and the other coauthor on the study, were able to analyze systematically the specification process controlled by the GRN and map out a master plan that, for the first time, shows the relationships between all the regulatory genes in specific parts of the embryo.

They studied sea-urchin embryos over a 24-hour period, beginning at hour eight of the embryo's existence. During this period, different physical domains exist in the embryo, each of which represents a future structure in the body, like the gut. All the regulatory genes known to exist in the sea-urchin genome and to be expressed in the embryo have been studied, and it was found that certain regulatory genes are expressed in the cells of each domain. Some of the domains will express certain regulatory genes in common, but the combination of genes found in each domain is unique. In addition, they found that this process is dynamicwhere the genes are expressed changes over time. For example, two genes that are coexpressed in one domain at an early stage of the process may then be expressed in different domains at a later stage.

"It's like you are building a complicated edifice," explains Davidson. "And before anything is actually there, the building instructions have already been handed to all the workers. They all know what they are going to have to do once the bulldozer comes in and starts moving earth around."

The team focused on pinning down the precise regulatory genes in the progression of pre-gut cells (which eventually form the gut), following them from their initial stage as undifferentiated cells, to the point of gastrulation. During gastrulation the endoderm cells reorganize from a single layer into an internal tube with three regions that serve as the foundation for the future foregut, midgut, and hindgut structures. The researchers were able to pinpoint which regulatory genes were expressed at which specific times in the 24-hour period, and how thos
'/>"/>

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology
Source:Eurekalert  

0

GOOD

Page: 1 2 3 4

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. NSF funds new Center for the Physics of Living Cells at Illinois
3. When cells go bad
4. The role of stem cells in renewing the cornea
5. Breast cancer cells recycle to escape death by hormonal therapy
6. Models of eel cells suggest electrifying possibilities
7. Scientists identify a molecule that coordinates the movement of cells
8. Form of Crohns disease traced to disabled gut cells
9. Cold Spring Harbor Laboratory scientists trace a novel way cells are disrupted in cancer
10. Researchers design artificial cells that could power medical implants
11. Stabilizing force for good communication between neurons and muscle cells found
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
From pre-gut cells to glory
(Date:5/21/2013)... researchers have developed a new method for delivering ... in the cell surface. The technique could find ... biological fields. , Bulk electroporation a technique ... nanopores in the cell membrane that are caused ... an increasingly popular method of cell transfection. (Cell ...
(Date:5/21/2013)... the University of Illinois at Chicago College of Medicine will ... fat -- its main energy source -- and how changes ... a new $2 million, 4-year grant from the National Heart, ... how it uses fuel for energy. These changes may play ... are different in men and women, says E. Douglas Lewandowski, ...
(Date:5/21/2013)... gathering of biomass experts , Where? ... When? 03-07 June 2013 , ... resource assessment, market and policy developments, manufacturing and installation, ... and benefiting from its 2013 edition from a record ... 60 countries, more than 240 plenary and oral presentations, ...
Breaking Biology News(10 mins):Single-cell transfection tool enables added control for biological studies 2Do men's and women's hearts burn fuel differently? 221st European Biomass Conference and Exhibition 221st European Biomass Conference and Exhibition 321st European Biomass Conference and Exhibition 4
... developed a new version of a medication, first isolated from ... pill form to relieve the most severe forms of pain ... on the topic appears in the current issue of Chemical ... Senior Editor Bethany Halford notes that a sea snails, saliva ...
... Genetic investigators say the partnership between people and the ancestors ... establish kingdoms, but by mobile, pastoral people who had to ... in northern Africa more than 5,000 years ago. The ... Proceedings of the Royal Society B , paint a surprising ...
... eat anything they want and never gain a pound, while ... foods? You may be seeing things correctly after all. ... Genetics ( http://www.genetics.org ), this may have a ... interacting with diet, rather than diet alone, are the main ...
Cached Biology News:Ancient DNA identifies donkey ancestors, people who domesticated them 2Ancient DNA identifies donkey ancestors, people who domesticated them 3Ancient DNA identifies donkey ancestors, people who domesticated them 4Why fad diets work well for some, but not others 2
(Date:5/22/2013)... MA (PRWEB) May 22, 2013 Cambridge ... present at last week’s “Data Demonstration Day” on Capitol Hill, ... Semantics joined EMC, Google, Microsoft and others to showcase how ... proposed Digital Accountability and Transparency Act (DATA Act). , Originally ... Issa (R-CA) and Sen. Mark Warner ...
(Date:5/22/2013)... 2013  Superior Controls, Inc. has been named ... NH Magazine.  For the past 22 years, the ... themselves with extraordinary business and civic excellence. ... honor," said Rick Pierro , ... this award is a reflection of Superior Controls, ...
(Date:5/22/2013)... (PRWEB) May 22, 2013 ... sound therapy for tinnitus treatment. AudioNotch is pleased ... . With clinic locations in both British Columbia ... of audiology and hearing services. AudioNotch's tinnitus treatment ... , Upon entering a Destination Hearing clinic, patients ...
(Date:5/22/2013)... PA (PRWEB) May 22, 2013 Envera ... as Fermentation Manager. Mr. McErlean has an extensive ... of leadership positions throughout his career. , ... are very pleased to have Mike join our team”. ... installed large scale fermentation and downstream processing ...
Breaking Biology Technology:Cambridge Semantics Underscores Need for Smart Data during “Data Demonstration Day” on Capitol Hill 2Superior Controls of Seabrook, NH named Business of the Year for 2013 by Business NH Magazine 2AudioNotch Tinnitus Treatment Launches Partnership With Destination Hearing 2Envera Appoints Michael McErlean Fermentation Manager 2
... with small companies and startups, far too often it ... the cornerstone of any companys long-term survival program. If ... training takes priority in these companies. , ,The ... can become obsolete just as fast! As new computer ...
... computers and Internet programming? Is tech still an exciting space ... first experience with computers was an introductory programming class in ... and the fledgling Internet when I started college in 1985. ... find computers, programming and the business of information technology as ...
... issue of the journal Science, could help mitigate disaster by ... furniture, evacuate buildings, divert aircraft, stop trains, shut down pipelines ... chemicals. , ,The system is based on TriNet ... southern California. , ,"An early warning system is the ...
Cached Biology Technology:The Big Differentiator, Training! 2Interview: Billpoint Founder Jason May on eBay, Open Source 2Interview: Billpoint Founder Jason May on eBay, Open Source 3Interview: Billpoint Founder Jason May on eBay, Open Source 4Wisconsin Researcher Co-Develops Earthquake Alarm 2Wisconsin Researcher Co-Develops Earthquake Alarm 3Wisconsin Researcher Co-Develops Earthquake Alarm 4
RAB32, member RAS oncogene family, mRNA (cDNA clone MGC:13500 IMAGE:4280407), complete cds...
APOPTAG® Plastic Coverslips are designed to be custom fitted to the specific APOPTAG® kit application. Each coverslip has 2.5 x 1 dimensions....
Recombinant Mouse TGF-beta RII/(human) Fc Chimera, CF...
Human Norrin Biotinylated Affinity Purified PAb Protein Family: Other Growth Factors, Other Wnt-related Molecules...
Biology Products: