Navigation Links
From pre-gut cells to glory
Date:6/3/2011

Cell Biology at Caltech and the other coauthor on the study, were able to analyze systematically the specification process controlled by the GRN and map out a master plan that, for the first time, shows the relationships between all the regulatory genes in specific parts of the embryo.

They studied sea-urchin embryos over a 24-hour period, beginning at hour eight of the embryo's existence. During this period, different physical domains exist in the embryo, each of which represents a future structure in the body, like the gut. All the regulatory genes known to exist in the sea-urchin genome and to be expressed in the embryo have been studied, and it was found that certain regulatory genes are expressed in the cells of each domain. Some of the domains will express certain regulatory genes in common, but the combination of genes found in each domain is unique. In addition, they found that this process is dynamicwhere the genes are expressed changes over time. For example, two genes that are coexpressed in one domain at an early stage of the process may then be expressed in different domains at a later stage.

"It's like you are building a complicated edifice," explains Davidson. "And before anything is actually there, the building instructions have already been handed to all the workers. They all know what they are going to have to do once the bulldozer comes in and starts moving earth around."

The team focused on pinning down the precise regulatory genes in the progression of pre-gut cells (which eventually form the gut), following them from their initial stage as undifferentiated cells, to the point of gastrulation. During gastrulation the endoderm cells reorganize from a single layer into an internal tube with three regions that serve as the foundation for the future foregut, midgut, and hindgut structures. The researchers were able to pinpoint which regulatory genes were expressed at which specific times in the 24-hour period, and how thos
'/>"/>

Contact: Deborah Williams-Hedges
debwms@caltech.edu
626-395-3227
California Institute of Technology
Source:Eurekalert  

Page: 1 2 3 4

Related biology news :

1. Jefferson scientists deliver toxic genes to effectively kill pancreatic cancer cells
2. NSF funds new Center for the Physics of Living Cells at Illinois
3. When cells go bad
4. The role of stem cells in renewing the cornea
5. Breast cancer cells recycle to escape death by hormonal therapy
6. Models of eel cells suggest electrifying possibilities
7. Scientists identify a molecule that coordinates the movement of cells
8. Form of Crohns disease traced to disabled gut cells
9. Cold Spring Harbor Laboratory scientists trace a novel way cells are disrupted in cancer
10. Researchers design artificial cells that could power medical implants
11. Stabilizing force for good communication between neurons and muscle cells found
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
From pre-gut cells to glory
(Date:9/23/2014)... tissues during the healing process, cells must be ... scientists believed this communication happened primarily through chemical ... the University of Pittsburgh have found that another ... not more crucial. The findings, published in this ... National Academy of Sciences , could lead to ...
(Date:9/23/2014)... cow rumens and termite guts for microbes that can ... of next-generation biofuels, but some of the best microbial ... researchers report. , Their study , reported in ... , is the first to use biochemical approaches to ... can digest fiber, breaking it down into simple sugars ...
(Date:9/23/2014)... vegetable consumption could be as good for your mental ... research, conducted by the University of Warwick,s Medical School ... published by BMJ Open focused on mental ... were consistently associated with an individual,s fruit and vegetable ... ate five or more portions of fruit and vegetables ...
Breaking Biology News(10 mins):The mechanics of tissue growth 2Search for better biofuels microbes leads to the human gut 2Search for better biofuels microbes leads to the human gut 3Eating five a day may keep the blues away 2
... 11, 2012) The naked mole rat, a curiously strange, ... or rat. Scientists at The University of Texas Health Science ... continue to explore this mystery. On May 2 a ... machines for protein disposal called proteasome assemblies differ ...
... ON Lawson Health Research Institute announced today that it ... the Bill & Melinda Gates Foundation. Dr. Gregor Reid ... receive funding from the Gates Foundation. The research ... the nutrient rich plant called Moringa on the health outcomes ...
... A brain study in infant rats demonstrates that the ... new questions about using the first-line drug to treat ... Neurology EarlyView posted online May 11, researchers at ... drug phenobarbital given to rat pups about a week ...
Cached Biology News:Scientists find differences in naked mole rat's protein disposers 2Lawson recieves Grand Challenges Explorations grant for groundbreaking research 2Study raises questions about use of anti-epilepsy drugs in newborns 2Study raises questions about use of anti-epilepsy drugs in newborns 3
(Date:9/23/2014)... September 23, 2014 Erlab , ... personnel since 1968 and Burdinola, supplier of laboratory furniture ... new filtered fume hood. , By integrating ... hood, Burdinola will now offer an innovative solution utilizing ... range of chemicals, best-in-class detection technology, and communication for ...
(Date:9/23/2014)... 2014 ATCC, the premier global biological ... two important appointments to the senior leadership team. Barbie ... Strategy and Technology and Dr. Maryellen de Mars also ... Center. Both roles are new positions at ATCC. ... CEO at ATCC described the additions as part of ...
(Date:9/23/2014)... 23, 2014 Follow us ... steady popularity the world over, due to its ... in the marketplace is expected to come from ... developing countries. Several sub-Saharan countries in the African ... already implemented genetically engineered crop production strategies. Rising ...
(Date:9/23/2014)... 2014 News Facts , ... devoted to genome-based research for human health and disease, ... taking a bite out of oral cancer with its world-class ... India with the help of state-of-the-art solution ... (DDN). , To fuel its cutting-edge cancer research, the ...
Breaking Biology Technology:Erlab Partners with Burdinola to Deliver an Innovative Filtered Fume Hood 2ATCC Announces New Appointments to its Leadership Team 2ATCC Announces New Appointments to its Leadership Team 3Rising Focus on Food Security Spurs Growth in the Global Agricultural Biotechnology Market, According to New Report by Global Industry Analysts, Inc. 2Rising Focus on Food Security Spurs Growth in the Global Agricultural Biotechnology Market, According to New Report by Global Industry Analysts, Inc. 3Rising Focus on Food Security Spurs Growth in the Global Agricultural Biotechnology Market, According to New Report by Global Industry Analysts, Inc. 4National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 2National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 3National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 4National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 5
... made tremendous scientific advances by dissecting apart the ... at the University of Wisconsin-Madison College of Engineering ... the pieces back together, mathematically. , John Yin, ... computer models of a relatively simple virus to ...
... SCOTTSDALE, Ariz., Feb. 6 Cancer Clinics of ... community oncologists, announced the completion of its 62nd ... leading oncology disease states at the 4th Annual ... oncology group is now fully prepared to launch ...
... LLC, a clinical-stage drug development company commercializing first-in-class ... completion of a $2.9 million private placement. ... and clinical programs for its lead drug compound, ... David G. Kalergis, Chief Executive Officer of Diffusion ...
Cached Biology Technology:Mathematical models reveal how organisms transcend the sum of their genes 2Cancer Clinics of Excellence (CCE) Releases 62nd Evidence-Based Treatment Protocol 2Diffusion Pharmaceuticals Announces Completion of a $2.9 Million Private Placement and Company Presentations at Upcoming Industry Conferences in Geneva, Switzerland and Naples, Florida 2Diffusion Pharmaceuticals Announces Completion of a $2.9 Million Private Placement and Company Presentations at Upcoming Industry Conferences in Geneva, Switzerland and Naples, Florida 3
Mouse monoclonal [4i144] to HLA Class II DQ1 7 ( Abpromise for all tested applications). Antigen: Full length protein (Human): HLA Class 2 Antigen DQ1,7....
ASCIZ...
Goat polyclonal to CHMP5 ( Abpromise for all tested applications). Antigen: Synthetic peptide: C-NKDGVLVDEFGLPQ, corresponding to C terminal amino acids 202-215 of Human CHMP5 Entrez GeneID: ...
...
Biology Products: