Navigation Links
From brains to behavior: Cold Spring Harbor Protocols features methods for neuroscience research
Date:10/1/2007

COLD SPRING HARBOR, N.Y. (Mon., Oct. 1, 2007) Research in the field of neuroscience is constantly expanding to provide knowledge about biological mechanisms that underlie our ability to experience and interact with the world around us. To facilitate such research, two neuroscience methods are featured in this months release of Cold Spring Harbor Protocols. Both are freely accessible online (www.cshprotocols.org) and include movie clips that help to illustrate the procedures.

The first protocol, available at http://www.cshprotocols.org/cgi/content/full/2007/20/pdb.prot4848, describes a step-by-step approach to prepare brain slices from rats or mice for growth in culture. Brain slice cultures, which are easy to prepare and maintain for several weeks or even months in the lab, allow researchers to examine the structure and function of neurons in their native environment.

The brain slice culture protocol was contributed by Dr. Michael Daileys group from the University of Iowa (http://www.biology.uiowa.edu/daileylab). His lab uses brain slice cultures in conjunction with high-resolution imaging and staining techniques to investigate changes that occur during the development of the central nervous system, as well as changes that occur after injury to the nervous system. Brain slice cultures can also be used to test the effects of various drugs or genetic backgrounds on brain function.

The second featured protocol is from Dr. Leslie Griffiths lab at Brandeis University (http://www.bio.brandeis.edu/griffithlab). It describes how to properly assess courtship behavior in male fruit flies. Because the behavior of male fruit flies is dependent on many environmental stimuli, it is important to measure courtship behavior under highly controlled conditions. Griffiths protocol describes how to control visual input, for example, by manipulating the light conditions under which the experiment takes place.

Griffiths protocol, freely available at http://www.cshprotocols.org/cgi/content/full/2007/20/pdb.prot4847, also describes how to assemble a courtship chamber and discusses strategies for observing and measuring courtship behavior. It can be used to evaluate the effects of prior experience and genetic background on courtship, and will be useful to researchers who are interested in understanding the biological basis of behavior.


'/>"/>

Contact: Maria Smit
smit@cshl.edu
516-422-4127
Cold Spring Harbor Laboratory
Source:Eurekalert

Related biology news :

1. Bird Brains Show How Trial and Error May Contribute to Learning
2. Birds brains reveal source of songs
3. Supercomputers to focus brains on AIDS dilemma
4. Mice brains shrink during winter, impairing some learning and memory
5. Bees, Brains and Addiction
6. Divergent life history shapes gene expression in brains of salmon
7. Jumping genes contribute to the uniqueness of individual brains
8. Experts discuss use of human stem cells in ape and monkey brains
9. Brains response to visual stimuli helps us to focus on what we should see, rather than all there is to see
10. Sharp older brains are not the same as younger brains
11. Brainstem blocks pain to protect key behaviors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2016)... 29, 2016 LegacyXChange, Inc. (OTC: ... and SelectaDNA/CSI Protect are pleased to announce our successful ... a variety of writing instruments, ensuring athletes signatures against ... collectibles from athletes on LegacyXChange will be assured of ... DNA. Bill Bollander , CEO states, ...
(Date:3/22/2016)... , March 22, 2016 ... research report "Electronic Sensors Market for Consumer Industry by ... & Others), Application (Communication & IT, Entertainment, ... - Global Forecast to 2022", published by ... is expected to reach USD 26.76 Billion ...
(Date:3/21/2016)... , March 22, 2016 ... with passcodes for superior security   ... leading provider of secure digital communications services, today announced ... technology and offer enterprise customers, particularly those in the ... recognition and voice authentication within a mobile app, alongside, ...
Breaking Biology News(10 mins):
(Date:5/4/2016)... WHIPPANY, N.J. , May 4, 2016 /PRNewswire/ ... evaluating its oncology compound Stivarga ® (regorafenib) ... hepatocellular carcinoma (HCC) has met its primary endpoint ... The study, called RESORCE, evaluated the efficacy and ... disease has progressed after treatment with sorafenib. The ...
(Date:5/4/2016)... May 4, 2016 According to ... "Metabolomics Market - Global Industry Analysis, Size, Share, Growth, ... is anticipated to expand at a CAGR of 17.1% ... by 2024. Metabolomics is the extensive study ... biofluids, tissues or organisms. Together, these small molecules and ...
(Date:5/4/2016)... NY (PRWEB) , ... May 04, 2016 , ... ... leveraged recent innovations in biotechnology to help treat hormonal and stress related hair ... Nutrafol® has captured the hearts of key opinion leaders in the medical and ...
(Date:5/3/2016)... ... May 03, 2016 , ... ... development, skill-building and compliance training platform on mobile devices, today released a new ... Regulatory Requirements for Medical Devices. The course is essential for owners or operators ...
Breaking Biology Technology: