Navigation Links
From brains to behavior: Cold Spring Harbor Protocols features methods for neuroscience research
Date:10/1/2007

COLD SPRING HARBOR, N.Y. (Mon., Oct. 1, 2007) Research in the field of neuroscience is constantly expanding to provide knowledge about biological mechanisms that underlie our ability to experience and interact with the world around us. To facilitate such research, two neuroscience methods are featured in this months release of Cold Spring Harbor Protocols. Both are freely accessible online (www.cshprotocols.org) and include movie clips that help to illustrate the procedures.

The first protocol, available at http://www.cshprotocols.org/cgi/content/full/2007/20/pdb.prot4848, describes a step-by-step approach to prepare brain slices from rats or mice for growth in culture. Brain slice cultures, which are easy to prepare and maintain for several weeks or even months in the lab, allow researchers to examine the structure and function of neurons in their native environment.

The brain slice culture protocol was contributed by Dr. Michael Daileys group from the University of Iowa (http://www.biology.uiowa.edu/daileylab). His lab uses brain slice cultures in conjunction with high-resolution imaging and staining techniques to investigate changes that occur during the development of the central nervous system, as well as changes that occur after injury to the nervous system. Brain slice cultures can also be used to test the effects of various drugs or genetic backgrounds on brain function.

The second featured protocol is from Dr. Leslie Griffiths lab at Brandeis University (http://www.bio.brandeis.edu/griffithlab). It describes how to properly assess courtship behavior in male fruit flies. Because the behavior of male fruit flies is dependent on many environmental stimuli, it is important to measure courtship behavior under highly controlled conditions. Griffiths protocol describes how to control visual input, for example, by manipulating the light conditions under which the experiment takes place.

Griffiths protocol, freely available at http://www.cshprotocols.org/cgi/content/full/2007/20/pdb.prot4847, also describes how to assemble a courtship chamber and discusses strategies for observing and measuring courtship behavior. It can be used to evaluate the effects of prior experience and genetic background on courtship, and will be useful to researchers who are interested in understanding the biological basis of behavior.


'/>"/>

Contact: Maria Smit
smit@cshl.edu
516-422-4127
Cold Spring Harbor Laboratory
Source:Eurekalert

Related biology news :

1. Bird Brains Show How Trial and Error May Contribute to Learning
2. Birds brains reveal source of songs
3. Supercomputers to focus brains on AIDS dilemma
4. Mice brains shrink during winter, impairing some learning and memory
5. Bees, Brains and Addiction
6. Divergent life history shapes gene expression in brains of salmon
7. Jumping genes contribute to the uniqueness of individual brains
8. Experts discuss use of human stem cells in ape and monkey brains
9. Brains response to visual stimuli helps us to focus on what we should see, rather than all there is to see
10. Sharp older brains are not the same as younger brains
11. Brainstem blocks pain to protect key behaviors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/9/2016)... , June 9, 2016  Perkotek an innovation leader in attendance control systems ... seamlessly log work hours, for employers to make sure the right employees are actually ... http://photos.prnewswire.com/prnh/20160609/377486LOGO ... ... ...
(Date:6/3/2016)... LONDON , June 3, 2016 /PRNewswire/ ... Transport Management) von Nepal ... ,Angebot und Lieferung hochsicherer geprägter Kennzeichen, einschließlich ... weltweit führend in der Produktion und Implementierung ... an der Ausschreibung im Januar teilgenommen, aber ...
(Date:6/2/2016)... 2016 Perimeter Surveillance & Detection ... Physical Infrastructure, Support & Other Service  The ... offers comprehensive analysis of the global Border Security ... revenues of $17.98 billion in 2016. Now: ... leader in software and hardware technologies for advanced video ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... DIEGO , June 24, 2016 ... more sensitively detects cancers susceptible to PARP inhibitors ... circulating tumor cells (CTCs). The new test has ... HRD-targeted therapeutics in multiple cancer types. ... targeting DNA damage response pathways, including PARP, ATM, ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... its second eBook, “Clinical Trials Patient Recruitment and Retention Tips.” Partnering with experienced ... this eBook by providing practical tips, tools, and strategies for clinical researchers. , ...
(Date:6/23/2016)... , June 23, 2016 /PRNewswire/ - FACIT ... Ontario biotechnology company, Propellon Therapeutics ... development and commercialization of a portfolio of first-in-class ... Epigenetic targets such as WDR5 represent an exciting ... significantly in precision medicine for cancer patients. Substantial ...
(Date:6/23/2016)... ... June 23, 2016 , ... Charm Sciences, Inc. is pleased ... received AOAC Research Institute approval 061601. , “This is another AOAC-RI approval of ... Salter, Vice President of Regulatory and Industrial Affairs. “The Peel Plate methods perform ...
Breaking Biology Technology: