Navigation Links
From alpaca to zebra finch -- a decade of cataloguing life's diversity
Date:3/31/2010

Today's publication in Nature of the genetic blueprint for the zebra finch marks 10 years of success for the Ensembl project in helping researchers to navigate the genomes of a Noah's Ark of species.

Ensembl, a genome annotation system co-developed and jointly run by the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust Sanger Institute, played a major part in finding the genes and other functionally important features in the zebra finch genome. For zebra finch, only the second bird to have its genome fully sequenced after the chicken, this interpretation of the genetic code has enabled the sequencing consortium to identify genes expressed in the zebra finch brain that may be responsible for vocalising messages: zebra finches communicate by singing whereas chickens cannot.

"Trying to navigate a genome that has not been annotated with important features such as genes and regulatory regions is a little bit like trying to read a map missing all the labels," explains Paul Flicek, joint head of Ensembl and leader of the Vertebrate Genomics team at EMBL-EBI. "Without this annotation, the data gathered from sequencing projects would remain undecipherable."

Ensembl, which was originally created as a means of cataloguing the genes in the human genome, now contains the complete genetic codes of more than 50 animals. In addition to zebra finch, Ensembl has unravelled the genomes of organisms ranging in complexity from the humble nematode worm through the duck billed platypus to ourselves.

"Genome analysis and comparison is key to linking genes to function and explaining why species differ from each other," says Steve Searle, joint head of Ensembl and of Vertebrate Annotation at the Wellcome Trust Sanger Institute "In addition to helping us know more about evolutionary relationships and genetic diversity, it also provides the tools to tackle disease at the genetic level."

"Over 10 years Ensembl has become part of the infrastructure of biological research," says Tim Hubbard, Head of Informatics at the Wellcome Trust Sanger Institute. "Looking back it's hard to imagine research before genomes and genome browsers."

Combining information held in Ensembl with the related Ensembl Genomes resource for the genomes of bacteria, fungi, plants, metazoa and protists launched by EMBL-EBI last year, every sequenced genome provides another jigsaw piece in cataloguing the genetic diversity of life.


'/>"/>

Contact: Louisa Wright
louisa@ebi.ac.uk
44-122-349-4665
European Molecular Biology Laboratory
Source:Eurekalert

Related biology news :

1. Zebrafish to shed light on human mitochondrial diseases
2. Study shows how the zebrafish gets his stripe
3. New national map shows relative risk for zebra and quagga mussel invasion
4. New map outlines risk of zebra mussel invasion
5. A screening strategy using zebrafish targets genes that protect against hearing loss
6. Deadly genetic disease prevented before birth in zebrafish
7. Zebra Technologies Enters Into Revolving Credit Agreement to Support Company Growth
8. Digital zebrafish embryo provides the first complete developmental blueprint of a vertebrate
9. NIH grants Phylonix Phase II SBIR to develop high-throughput in vivo zebrafish assays
10. AZTI-Tecnalia coordinates a platform promoting the use of zebrafish in scientific research
11. Alzheimer cell death in Zebrafish: Demise of neurons observed live for the first time
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/23/2016)... WAKEFIELD, Massachusetts , March 23, 2016 ... kombiniert im Interesse erhöhter Sicherheit Gesichts- und ... Xura, Inc. (NASDAQ: MESG ... heute bekannt, dass das Unternehmen mit SpeechPro ... insbesondere aus der Finanzdienstleistungsbranche, wird die Möglichkeit ...
(Date:3/18/2016)... -- --> --> Competitive ... Unmanned Vehicles, Physical infrastructure and Perimeter Surveillance & Detection Systems ... security market and the continuing migration crisis in the ... has led visiongain to publish this unique report, which ... defence & security companies in the border security market ...
(Date:3/14/2016)... NXTD ) ("NXT-ID" or the "Company"), ... the airing of a new series of commercials on Time ... 21 st .  The commercials will air on Bloomberg TV, ... the Street show. --> NXTD ) ("NXT-ID" or ... market, announces the airing of a new series of commercials ...
Breaking Biology News(10 mins):
(Date:4/28/2016)... ... 28, 2016 , ... As part of an ongoing global ... expanding its LATAM network and logistics capabilities. Enhancements have been made to ... trial projects. , The expansion will provide unmatched clinical trial logistics services for ...
(Date:4/27/2016)... (PRWEB) , ... April 27, 2016 , ... Cambridge ... by semantic web technology, today announced that it has been named to The Silicon ... sciences, financial services and other markets, Cambridge Semantics serves the needs of end users ...
(Date:4/27/2016)... ... April 27, 2016 , ... The Pittcon Organizing Committee is pleased ... has been a volunteer member of Committee since 1987. Since then, he has served ... and treasurer and was chairman for both the program and exposition committees. In his ...
(Date:4/27/2016)... , April 27, 2016 ... NSK) (OTCPink: NSKQB) ( Frankfurt : ... ihre Pressemitteilung vom 13. August 2015 die Genehmigung ... Finanzen um zusätzliche 200.000.000 Einheiten auf 400.000.000 Einheiten ... zu bringen. Davon wurden 157.900.000 Einheiten mit dem ...
Breaking Biology Technology: