Navigation Links
From DNA to diagnosis
Date:3/18/2014

nomes, but also tumor genomes and "metagenomes" from infectious disease agents such as viruses and bacteria.

Knowing the DNA sequence of a cancer patient's tumor, for example, may reveal a personalized treatment plan for combatting the disease. Pinpointing tiny sequence variations in personal genomes will expose inherited diseases that, in some cases, may be life-threatening.

Together with Omicia, Inc., the USTAR Center for Genetic Discovery is building a web accessible informatics platform, called Opal, to distill genome data to clinically relevant findings. Opal is powered by VAAST, a proven disease gene finder algorithm invented by Yandell. Launched less than two years ago, VAAST has successfully identified causes of inherited diseases, including hard-to-diagnose rare diseases, and is used at 251 institutions worldwide.

"We are building the information highway that is necessary for taking genetic DNA information from the sequencing machine all the way to clinical use," said Marth.

The same features that make VAAST a robust genome interpretation tool make it a powerful engine for disease discovery. The center is collaborating with Utah Genome Project investigators, who leverage an enormous collection of genealogical and health records dating from pioneer times, to search for the genetic causes of cancers, immune, lung, heart, and other inherited diseases.

"Once we identify the genetic causes of disease, we can work towards better diagnoses, more effective treatment, and sometimes curing those diseases," said said Lynn Jorde, Ph.D., Executive Director of the Utah Genome Project.

The USTAR Center for Genetic Discovery eventually anticipates commercializing its full suite of software tools, and becoming a top genomic health data service provider for medical centers nationwide.


'/>"/>

Contact: Julie Kiefer
jkiefer@neuro.utah.edu
801-597-4258
University of Utah Health Sciences
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Test to improve peanut allergy diagnosis
2. Tiny electrical sensors could signal faster MRSA diagnosis
3. Researchers identify genes that may help in ovarian cancer diagnosis and prognosis
4. Promising developments in early diagnosis and treatment of mesothelioma
5. A new diagnosis for Frida Kahlos infertility
6. Sequencing works in clinical setting to help -- finally -- get a diagnosis
7. Exome sequencing gives cheaper, faster diagnosis in heterogeneous disease
8. Obesity is major contributor to heart disease, impediment to diagnosis and treatment
9. Plants provide accurate low-cost alternative for diagnosis of West Nile Virus
10. Privately owned genetic databases may hinder diagnosis and bar the way to the arrival of personalized medicine
11. Detection, analysis of cell dust may allow diagnosis, monitoring of brain cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
From DNA to diagnosis
(Date:7/31/2015)... Den 10. internationale konference om Genomik (ICG-10, ... - 25. oktober i Shenzhen , ... i år. Siden starten i 2006 er ICB blevet ... og er en af de mest dynamiske, entusiastiske og ... nylige gennembrud og fremskridt inden for ,omik,-forskning, som yderligere ...
(Date:7/31/2015)... China , 31 de julio de 2015 /PRNewswire/ ... Genómica (ICG-10,  www.icg-10.org ) del 22 al 25 de ... . La conferencia celebra su décimo aniversario ... ha convertido en una de las reuniones anuales más ... y es una de las conferencias científicas más dinámicas, ...
(Date:7/31/2015)... julho de 2015 A 10 a. ... realizada pela BGI de 22-25 de outubro de 2015, em ... A conferência está celebrando seu 10 o. aniversário este ... tornou uma das reuniões mais influentes do mundo no ... dinâmicos, entusiastas e prazerosos. A ICG-10 ...
Breaking Biology News(10 mins):Den 10. internationale konference om Genomics (ICG-10) åbner i oktober 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 3A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 2A 10a. Conferência Internacional sobre Genômica (ICG-10) será em outubro 3
... Cell biologist Carolyn Machamer, Ph.D is The ... her creative work on coronaviruses. Specifically, Machamer studies how ... against it. While most coronaviruses result only ... respiratory syndrome (MERS) and SARS can lead to fatal ...
... BioClaim, Inc. announced as part of its ongoing effort ... of Florida , a subsidiary of WellPoint, ... select physician offices in the state.  "We greatly ... Scott Kimmel , executive vice president and general counsel of ...
... Wash. Two nearly identical softballs, both approved for league ... player,s head., Those are the findings from a study conducted ... Materials Engineering and project engineer Derek Nevins that they will ... this month in Hong Kong. Their work was published in ...
Cached Biology News:BioClaim, Inc. Signs Biometric Software Contract with Amerigroup Florida 2BioClaim, Inc. Signs Biometric Software Contract with Amerigroup Florida 3Researchers hit virtual heads to make safer games 2
(Date:7/30/2015)... , July 30, 2015 According ... Product (Software, Molecular Modeling, PB/PK, PKPD, Trial Design, Toxicity ... Development, Preclinical, Clinical Trial), by End Users - Global ... is expected to reach USD 2,107.99 million by 2020 ... of 15.29%. Browse more than ...
(Date:7/30/2015)... -- With over 60,000 customers across the globe, ISN improves the efficiency and effectiveness of ... than 60,000 safe and reliable contractors in over 80 countries. ... ... Over 60,000 Worldwide Customers In More ... Headquartered in Dallas, TX , ISN has additional offices ...
(Date:7/30/2015)... New York, NY (PRWEB) , ... July 30, 2015 , ... As part of its ... raw material and technical service business units, Whitehouse Laboratories is pleased ... facility will be adjacent to the Container Center of Excellence and will be strictly dedicated ...
(Date:7/29/2015)... According to a new market research report, ,Global ... published by Mordor Intelligence, the Global market is expected to ... with North America being the largest ... market size. The Global market for Stem Cells is expected ... of (2015-2020).      (Logo: http://photos.prnewswire.com/prnh/20150428/740799) , ...
Breaking Biology Technology:Biosimulation Market Worth 2,107.99 Million USD by 2020 2Biosimulation Market Worth 2,107.99 Million USD by 2020 3Biosimulation Market Worth 2,107.99 Million USD by 2020 4ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3Whitehouse Labs Formally Announces Plans to Open a Microbiological Laboratory 2Asia Pacific to Dominate the Global Stem Cell Market - Vericel Corporation, Ocata Therpeutics, Athersys Inc., Cryo-Cell International, Geron Corporation, StemCells, Inc. Among the Major Players 2Asia Pacific to Dominate the Global Stem Cell Market - Vericel Corporation, Ocata Therpeutics, Athersys Inc., Cryo-Cell International, Geron Corporation, StemCells, Inc. Among the Major Players 3
... Techne Corporation (NASDAQ: TECH ) (Techne) ... Tocris Holdings Limited and subsidiaries (Tocris), a leading supplier ... are used in both in-vitro and in-vivo experiments, to ... on making biologically active neuro- and bio-chemicals which are ...
... DNDN ) today reported results for the first quarter ended ... was $28.1 million compared to $21,000 for the quarter ended March ... quarter ended March 31, 2011 was $111.8 million, or $0.77 per ... quarter ended March 31, 2010 (which included a non-cash charge of ...
... Fla. and WAGENINGEN, Netherlands, May 2, 2011 ... global biotechnology company focused on the discovery, development, ... for the biopharmaceutical, biofuels and industrial enzyme industries, ... Dyadic Nederland B.V. ("Dyadic Netherlands"), has entered into ...
Cached Biology Technology:Techne Corporation Announces Acquisition 2Techne Corporation Announces Acquisition 3Techne Corporation Announces Acquisition 4Techne Corporation Announces Acquisition 5Dendreon Reports First Quarter 2011 Financial Results 2Dendreon Reports First Quarter 2011 Financial Results 3Dendreon Reports First Quarter 2011 Financial Results 4Dendreon Reports First Quarter 2011 Financial Results 5Dyadic Netherlands Enters Into R&D Collaboration With Sanofi Pasteur and EnGen Bio 2
200 μg per ml DNA in 10 SSPE, 2 Denhardt's...
... with an early protein. ... hours post-infection exhibiting an intranuclear ... intensity between 6-24 hours. ... coarsely granular staining. No ...
... Anti-AP-2 α, clone 8G8/5 GenBank ... Bacterially made human AP-2alpha/gamma fusion protein corresponding ... residues 278-450 of human AP-2γ Formulation: 0.1M ... azide before the addition of glycerol to ...
Parathyroid Hormone Receptor 2 [PTHR2]...
Biology Products: