Navigation Links
Free radicals in cornea may contribute to Fuchs dystrophy, most common cause of corneal transplants
Date:1/31/2011

ree radical process might be part of what is happening within the Fuchs dystrophy-plagued cornea. Free radicals are unstable molecules released by the body, which destabilize other molecules through a process known as oxidization, which causes cell death. Antioxidants are known to bind with and neutralize free radicals.

To test the theory, Jurkunas and her colleagues took numerous tissue samples from patients undergoing corneal transplants and tested them for evidence of free radical oxidation and subsequent tissue damage.

In the significant majority of specimens, the scientists found that the level of antioxidants was less than normal (or down-regulated). They also found evidence of high rates of damage to the cells' DNA, which is particularly susceptible to free radicals.

According to Jurkunas, the next step is to identify the specific antioxidants that would neutralize the free radicals involved in the damage and, therefore, could prevent or block their destructive action.

What should patients do in the meantime? While no conclusions should be drawn from these early results, Jurkunas recommends that patients at risk for Fuchs eat a healthy diet rich in leafy green vegetables, such as broccoli and Brussels sprouts, take multivitamins and wear UV protection outdoors.


'/>"/>

Contact: Patti Jacobs
pjacobs12@comcast.net
617-864-2712
Schepens Eye Research Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. Forget the antioxidants? McGill researchers cast doubt on role of free radicals in aging
2. Traits produced by melanin may signal the bearers capacity to combat free radicals
3. Stem cell therapy makes cloudy corneas clear, according to Pitt researchers
4. The role of stem cells in renewing the cornea
5. Study shows smaller rows contribute to more soybean yields in colder climates
6. UK researchers contribute to sequencing strawberry genome
7. Dodds contributes to new national study on nitrogen water pollution
8. Waterways contribute to growth of potent greenhouse gas
9. Scientists discover molecular switch that contributes to cellular aging process
10. Think saturated fat contributes to heart disease? Think again
11. In-country OB/GYN training programs contributed to retention of doctors in Ghana, U-M study shows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/4/2014)... research study examining only marketing directed at children ... restaurants has found that the majority of black, ... such marketing tactics. , Authored by Arizona State ... study is the first to examine the use ... of fast food restaurants and its relationship to ...
(Date:11/4/2014)...   Neurotechnology , a provider of high-precision ... version of its fingerprint matching algorithm has achieved ... evaluation organized by NIST. The MINEX test measures ... 378 fingerprint standard template format. MINEX compliance is ... the United States and ...
(Date:11/3/2014)... ANGELES , Nov. 3, 2014  NeuroSigma ... -based life sciences company focused on commercialization ... system for the treatment of neurological and ... of Industrial Property has issued a Notice of ... patent application is co-owned by NeuroSigma and the ...
Breaking Biology News(10 mins):Fast food marketing for children disproportionately affects certain communities 2Fast food marketing for children disproportionately affects certain communities 3Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 2Neurotechnology Places Second in Ongoing MINEX Ranking for Fingerprint Matching Algorithms 3NeuroSigma Receives Notice of Allowance from the Mexican Institute of Industrial Property Covering Subcutaneous Trigeminal Nerve Stimulation (sTNS) 2NeuroSigma Receives Notice of Allowance from the Mexican Institute of Industrial Property Covering Subcutaneous Trigeminal Nerve Stimulation (sTNS) 3
... Iowa - Some fisheries in the United States are ... to protect fish stocks, and Iowa State University researchers ... economic boon to the fishing industry., Quinn Weninger and ... costs under the old system and compared that to ...
... to the discovery of how to regenerate tissue damaged by ... PDGF as a key factor in the proliferation and transformation ... muscle and contributes to vessels. The study was published ... Proceedings of the National Academy of Sciences of ...
... computer gadgetry to monitor the ever-evolving landscape of our planet ... of a new knowledge exchange network being led by The ... by Dr Paul Aplin in the University,s School of Geography, ... Environment Research Council (NERC). It will focus on technology ...
Cached Biology News:New fisheries system will save about $20 million, Iowa State University researchers find 2New fisheries system will save about $20 million, Iowa State University researchers find 3Childrens Hospital LA discovers growth factor essential to epicardial cell function 2Keeping a watch on the world 2Keeping a watch on the world 3
(Date:11/24/2014)... SOUTH SAN FRANCISCO, Calif. , Nov. 24, 2014 /PRNewswire/ ... announced that Bonnie H. Anderson , president and chief ... the Piper Jaffray 26 th Annual Healthcare Conference on ... New York . The live audio ... website at http://investor.veracyte.com . Please connect to the website ...
(Date:11/24/2014)... November 24, 2014 Continental Clinical ... populations into clinical trials at its mid-Atlantic late-phase ... “Continental was created with the idea of closing ... fundamental role in medical advances," said Continental's CEO, ... experiment to the immortal cell line of Henrietta ...
(Date:11/24/2014)... (PRWEB) November 24, 2014 The ... ” from METTLER TOLEDO demonstrates how to reduce ... Power analytics and sample panel design can be ... chemistry and protect against corrosion and deposition. Dedicated ... a significant amount of panel space. Additionally, installing ...
(Date:11/24/2014)... -- Senior Vice President, General Manager for ... business acumen Elsevier , a world-leading ... services, congratulates Diane Bartoli , Senior Vice President ... Clinical Solutions, for being recognized in the 13 th ... of Profiles in Diversity Journal ® . ...
Breaking Biology Technology:Veracyte to Present at the Piper Jaffray 26th Annual Healthcare Conference 2At Continental Clinical Solutions, CEO Saleh Stevens Focuses on Diversity in Clinical Trial Recruitment at Maryland Site 2At Continental Clinical Solutions, CEO Saleh Stevens Focuses on Diversity in Clinical Trial Recruitment at Maryland Site 3New Video Shows How to Simplify Cycle Chemistry Sample Panels to Save Time and Costs 2Elsevier Clinical Solutions' Diane Bartoli Featured In Profiles in Diversity Journal's 13th Annual Women Worth Watching Issue 2Elsevier Clinical Solutions' Diane Bartoli Featured In Profiles in Diversity Journal's 13th Annual Women Worth Watching Issue 3
... Pa., Oct. 19 Tengion Inc. (Nasdaq: TNGN ... has appointed Richard E. Kuntz, MD, M.Sc., Senior Vice President ... (NYSE: MDT ), to its Board of Directors. ... oversees the company,s global regulatory affairs, health policy and reimbursement, ...
... The Davis Phinney Foundation ( http://www.davisphinneyfoundation.org ), a non-profit ... that help people to live well with Parkinson,s disease, ... " Exercise and Parkinson,s: Questions and Answers from the ... disorder experts in the fields of physical therapy and ...
... and European medical technology industry struggled to sustain historic ... improve overall net income by nearly 11% as companies ... fared better than many industries in the current economic ... industry,s long-standing business model. These and other findings are ...
Cached Biology Technology:Tengion Appoints Richard E. Kuntz, MD to its Board of Directors 2Tengion Appoints Richard E. Kuntz, MD to its Board of Directors 3Tengion Appoints Richard E. Kuntz, MD to its Board of Directors 4Davis Phinney Foundation Launches Exercise-Focused Tools to Help People Live Well With Parkinson's Disease 2Davis Phinney Foundation Launches Exercise-Focused Tools to Help People Live Well With Parkinson's Disease 3Davis Phinney Foundation Launches Exercise-Focused Tools to Help People Live Well With Parkinson's Disease 4Medtech Industry Successfully Weathering Challenges of Economic Downturn 2Medtech Industry Successfully Weathering Challenges of Economic Downturn 3Medtech Industry Successfully Weathering Challenges of Economic Downturn 4Medtech Industry Successfully Weathering Challenges of Economic Downturn 5
... Features Convenient platform for tube handling and ... x 0.2ml V-bottom tubes - 96 ... - Thermo-Fast® 96 Non-Skirted Plate ... - 48 x 0.5ml Thermo-Tubes Multiple workstations can ...
... The Pro upgrade for Shimadzu Phoretix 2D, ... advanced statistical tools for comparative gel analysis ... Data base add on component ... (Oracle version 9i release 2 client software). ...
... systems provide linking and labelling reagents ... specific primary antibodies for visualising cellular ... accomplished using an ultra-sensitive indirect labelling ... technology. Secondary antibodies are polymerised directly ...
... Enzyme concentration - 5 units/µL ,• High ... yields ,• Leaves an 'A' overhang ,• ... which exhibits very high activity in primer ... ensure the quality of the enzyme, each ...
Biology Products: