Navigation Links
Franklin Square to study airway bypass procedure for severe emphysema
Date:10/27/2008

October 27, 2008 (Baltimore, MD)Franklin Square Hospital Center announces the start of the EASE (Exhale Airway Stents for Emphysema) Trial to explore an investigational treatment for advanced widespread emphysema/COPD. The trial focuses on airway bypass, a bronchoscopic procedure designed to reduce lung hyperinflation and shortness of breath (the clinical hallmarks of emphysema/COPD) by making new pathways for trapped air to exit the lungs.

During the airway bypass procedure, new openings are created in the airway wall connecting the damaged lung tissue to the natural airway. These pathways are supported and kept open by Exhale Drug-Eluting Stents manufactured by Broncus Technologies, Inc. Patients could see an immediate improvement in dyspnea (shortness of breath).

"We are excited to be part of this study because currently there are limited treatment options for emphysema. Patients are often in poor physical condition, struggling with each breath," states William Krimsky, MD, director of Interventional Pulmonology at Franklin Square and principal investigator of the study. "By creating new pathways for airflow with the airway bypass procedure, we hope to reduce hyperinflation and improve lung function. If patients can breathe easier it is likely to improve their quality of life."

Emphysema, a component of COPD, is a chronic, progressive, and irreversible lung disease characterized by the destruction of lung tissue. The loss of the lungs' natural elasticity and the collapse of airways in the lung combine to make exhalation ineffective, leaving emphysema sufferers with hyperinflation because they are unable to get air out of their lungs. Breathing becomes inefficient and patients have to work very hard just to breathe making normal activities, like walking, eating or even bathing, difficult. There are few treatment options for most patients with emphysema and there is no cure.

"The airway bypass procedure could be an excellent option for those who are not suitable candidates for lung transplant surgery or who would possibly spend years on a lung transplant list," states Krimsky. "Given that emphysema, which permanently destroys lung function, is such a devastating disease -- any potential new treatment option could offer substantial relief to the millions who suffer."

Physicians commonly use bronchoscopes to examine the airways within the lungs. During the airway bypass procedure physicians will first use a Doppler probe inserted through the bronchoscope to identify a site in the airway that is away from blood vessels. A special needle is then used to make a small opening and an Exhale Drug-Eluting Stent is placed in the passageway to keep it open. The procedure involves placing up to six drug-eluting stents. The total time of the procedure is approximately two hours.

Although this procedure is still under clinical investigation, feasibility data suggest it may hold promise for patients with emphysema. Results from the open-label Exhale Drug-Eluting Stent feasibility study were published in the October 2007 issue of the Journal of Thoracic and Cardiovascular Surgery. Positive results included a statistically significant reduction in the amount of air trapped in the lungs and an improvement in breathing for patients at six months after the airway bypass procedure.


'/>"/>

Contact: Meghan Oreste
moreste@comcast.net
617-823-1441
Broncus Technologies
Source:Eurekalert  

Related biology news :

1. 55th anniversary of Nobel honoring double helix continues to overlook the late Rosalind Franklin
2. UMass Medical School researcher Victor Ambros receives Gairdner Award, Franklin Medal
3. Study may explain exercise-induced fatigue in muscular dystrophies
4. First comprehensive genomic study of common cold reveals new treatment targets
5. New study shows drinking your vegetables may be a solution to bridging the vegetable gap
6. New Study Reveals the Emotional Impact and Effectiveness of Negative Campaigning
7. Study: Elderly Women can increase strength but still risk falls
8. Greenhouse gas auction revenues can help cut Md. electric use significantly, says study
9. The Marine Mammal Center begins new leptospirosis study in California
10. UCSB study finds physical strength, fighting ability revealed in human faces
11. U of MN study shows link between gene variations and cancer survival
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Franklin Square to study airway bypass procedure for severe emphysema
(Date:2/3/2016)... , February 3, 2016 ... market research report "Automated Fingerprint Identification System Market by ... Search), Application (Banking & Finance, Government, Healthcare, and Transportation) ... MarketsandMarkets, the market is expected to be worth USD ... 21.0% between 2015 and 2020. The transformation and technology ...
(Date:2/2/2016)... 2016  BioMEMS devices deployed in hospitals ... medical screening and diagnostic applications, such as ... that facilitate and assure continuous monitoring without ... being bolstered through new opportunities offered by ... coupled with wireless connectivity and low power ...
(Date:2/2/2016)... , Feb. 2, 2016 Technology Enhancements Accelerate Growth ... analysis of the digital and computed radiography markets in ... , and Indonesia (TIM). It ... market size, as well as regional market drivers and ... discusses market penetration and market attractiveness, both for digital ...
Breaking Biology News(10 mins):
(Date:2/4/2016)... 2016 - New FDA action date of ... FDA action date of July 22, 2016   ... 22, 2016   - Lifitegrast has ... indicated for the treatment of signs and symptoms of dry eye ... potential to be the only product approved in the U.S. in the past decade indicated ...
(Date:2/4/2016)... ... ... Shimadzu Scientific Instruments will showcase several new products, including ... and present on the analysis of mycotoxins and medical cannabis at the Pittcon ... the Georgia World Congress Center in Atlanta, Georgia. , Attendees should stop ...
(Date:2/4/2016)... , Feb. 4, 2016 Beike Biotechnology, the ... medical institutions attended a ceremony in late 2015 to ... cell therapy in 2016. --> ... Translation Platform for Personalized Cell Therapy" was hosted by ... Production Center, both subsidiaries of Beike Biotechnology Co., Ltd. ...
(Date:2/4/2016)... and MENLO PARK, Calif. , Feb. ... ("DelMar" and the "Company"), a biopharmaceutical company focused on the ... it will present at the 18 th Annual ... 2016 at 10:00 a.m. EST in New York, ... president and CEO, will provide an update on the ongoing ...
Breaking Biology Technology: