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Fossilized human feces from 14th century contain antibiotic resistance genes
Date:2/27/2014

cs are common in nature, and Desnues suggests that the resistance genes may simply be protecting the gut bacteria from them.

"Our evidence demonstrates that bacteriophages represent an ancient reservoir of resistance genes and that this dates at least as far back as the Middle Ages," says Desnues.

"We were interested in viruses because these are 100 times more abundant than human cells in our bodies, but their diversity is still largely unexplored," says Desnues. "In the present study, we thus focused on the viral fraction of the coprolite by using, for the first time, a combination of electron microscopy, high-throughput sequencing and suicide PCR approaches."

Desnues and her collaborators are currently conducting further studies on the fungi and parasites in the coprolites, which she says will be of interest not only to microbiologists, but to historians, anthropologists, and evolutionists.

The genesis of the research was an urban renewal project in the city of Namur, Belgium, in which latrines dating back to the 1300s were discovered beneath a square.


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Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
Source:Eurekalert

Page: 1 2

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