Navigation Links
Forsyth team gains new insight on childhood dental disease
Date:2/27/2011

Researchers at The Forsyth Institute have made a significant discovery about the nature of childhood dental disease. The scientific studies led by Anne Tanner, BDS, Ph.D., identified a new pathogen connected to severe early childhood caries (cavities). This bacterium, Scardovia wiggsiae, was present in the mouths of children with severe early childhood caries when other known pathogens such as Streptococcus mutans were not detected. This research may offer the potential to intervene and halt the progression of disease.

Early childhood caries, ECC, is the most common chronic infectious disease of childhood in the United States. Severe ECC can destroy primary teeth, cause painful abscesses and is the major reason for hospital visits for young children. This condition disproportionately affects disadvantaged socio-economic groups. This research, which will be published in the April issue of Journal of Clinical Microbiology, provides new insight on the microbiota of severe early childhood caries.

Dental caries is caused by an interaction between bacteria, host susceptibility and a carbohydrate diet that contains large amounts of sugar. Dr. Tanner published an updated evaluation of the diet associated with severe-ECC in collaboration with Dr. Carole Palmer at Tufts University in the Journal of Dental Research in 2010. The bacterial species Streptococcus mutans is widely recognized as the primary pathogen in early childhood caries. However, it is also present in people without disease and is not detected in all cases of childhood caries. This suggests that other species such as S. wiggsiae are also disease causing pathogens.

"In my work, I have seen the tremendous public health impact of severe early childhood caries," said. Dr. Anne Tanner, Senior Member of Staff, Department of Molecular Genetics, The Forsyth Institute.

"Understanding the causes of severe dental decay in young children is th
'/>"/>

Contact: Jennifer Kelly
jkelly@forsyth.org
617-892-8602
Forsyth Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. Forsyth scientists support the Human Microbiome Project
2. Forsyth receives highly competitive challenge grants
3. Forsyth scientists suggest linkages between obesity and oral bacterial infection
4. Forsyth scientist receives major grant to support rapid, accurate, affordable test for tuberculosis
5. Forsyth scientists trigger cancer-like response from embryonic stem cells
6. Advanced Protection Against Document Fraud - ICAP Ocean Tomo Announces Auction of a Counterfeit Document Detection System
7. TCD scientists discover that self-eating cells safeguard against cancer
8. Vaccine made with synthetic gene protects against deadly pneumonia
9. NRL scientists elevate warfighter readiness against invisible threats
10. A race against time to find Apollo 14s lost voyagers
11. Photodynamic therapy against cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... affordable health care to reproductive technologies, the justice ... ability of people to identify key issues, articulate ... and find the most defensible ways forward. But ... these societal conversations?, The Hastings Center and the ... have teamed up to publish a series of ...
(Date:9/17/2014)... UT Arlington engineering professor and his doctoral student have ... can accumulate water collected from fog and dew., The ... world or deserts around the globe., Cheng Luo, professor ... Heng, PhD candidate in the same College of Engineering ... 25 edition of ACS, (American Chemical Society) ...
(Date:9/17/2014)... has developed, very cleverly, some lessons on how to ... said Joseph Shaw, director of the Optical Technology Center ... structures at the nanoscale, we,ll discover them." , Some ... August during a conference called "The Nature of Light: ... of the University of Arizona College of Optical Sciences. ...
Breaking Biology News(10 mins):Why bioethics literacy matters 2Why bioethics literacy matters 3Shorebird's beak inspires UT Arlington research on water collection 2Nature's designs inspire research into new light-based technologies 2Nature's designs inspire research into new light-based technologies 3
... may not be the answer to mitigating climate change by ... to an international team of plant biologists. The researchers found ... fungi (AMF) -- a type of fungus that is often ... then leads to higher decomposition rates of organic materials, said ...
... the methane on Earth comes from the ocean,s oxygen-rich waters, ... this potent greenhouse gas. Now researchers report that they have ... the most abundant microbes on the planet. The findings ... who made the discovery did not set out to explain ...
... part of the marine ecosystem, fostering biodiversity and protecting ... with pollution and harmful fishing practices, are one of ... One of the solutions to the crisis ... Tel Aviv University,s Department of Molecular Microbiology and Biotechnology, ...
Cached Biology News:Plants' fungi allies may not help store climate change's extra carbon 2Study identifies prime source of ocean methane 2Study identifies prime source of ocean methane 3Viruses could be the key to healthy corals 2
(Date:9/18/2014)... MA (PRWEB) September 18, 2014 ... Molecule Sequencing (tSMS™) technology, announced today the closing ... of investment, led by Genomic Diagnostic Technologies, will ... and diagnostic applications. , Founded in March 2013 ... and Bioinformatics Analyst at Helicos BioSciences, SeqLL has ...
(Date:9/18/2014)... Now a team led by an engineer at Michigan ... that will let scientists slash the cost of one ... Syringe pumps are used to dispatch precise amounts of ... a reaction. They can also cost hundreds or even ... of Michigan Tech students published the library of free ...
(Date:9/18/2014)... USC have developed a new microscopy technology that ... animals at higher-than-ever resolution. , Dubbed "Complementation Activated ... resolutions that are an order of magnitude finer ... the behavior of biomolecules at the nanometer scale. ... by Nature Communications , the researchers behind ...
(Date:9/18/2014)... for computing may have just taken an encouraging step ... led by chemist Stephen O,Brien have discovered new complex ... Combining both properties is very exciting scientifically for the ... devices that might ultimately be designed, in logic circuits ... material, however, has proved difficult until now. , Using ...
Breaking Biology Technology:SeqLL Closes Series-A Funding Round for Expansion of Single Molecule Sequencing 2Doing science just got cheaper -- and faster 2Scientists pioneer microscopy technique that yields fresh data on muscular dystrophy 2Oxides discovered by CCNY team could advance memory devices 2
... Inc., (TSX: IXS.V; OTC Bulletin Board: IXSBF),( http://www.ixsbio.com ... of monoclonal antibodies based on its Dynamic Cross ... a large scale,primate study of DXL625 (CD20), the ... study in cynomolgus monkeys of DXL625, an antibody,directed ...
... Odyssey Thera, Inc. announced,that it has received a ... progress a discovery stage drug candidate into,pre-clinical development. ... as part of the ongoing collaboration with Pfizer., ... of the collaboration with,Pfizer," said John K. Westwick, ...
... (OTC,Pink Sheets: AIMM) today reported a net loss of $86,000, ... ended June 30, 2008, compared with,a net loss of $62,000, ... months ended June 30, 2007. For the six months ended ... share basic and diluted, compared,with net loss of $54,000, or ...
Cached Biology Technology:InNexus Biotechnology Announces Launch of Large Scale Primate Study of DXL625 2AutoImmune Inc. Reports 2008 Second Quarter Financial Results 2AutoImmune Inc. Reports 2008 Second Quarter Financial Results 3
... a simple high performance method for removing ... without significant dilution of protein solution. ... Detergent-OUT Spin column and collect detergent free ... removing detergent from a maximum of 0.2 ...
... Chemicon Detergent-OUT SDS Kit is a simple ... protein solutions. Removes detergents without significant ... the protein solution on the Detergent-OUT Spin ... Med columns are suitable for removing ...
... from frozen embedded tissue blocks, which are ... ensure the highest quality. Tissues of each ... sectioned at a thickness of 7 microns ... large (3-5 mm in diameter) in comparison ...
... Zyagen tissue microarrays are derived from frozen ... rigorous quality control procedures to ensure the ... manually assembled in one block, sectioned at ... coated slides. Sections are large (3-5mm in ...
Biology Products: