Navigation Links
For young boys with cancer, testicular tissue banking may be option to preserve fertility
Date:11/9/2009

f Veterinary Medicine, an internationally renowned expert in genetics and reproduction.

Starting in January 2008, a multidisciplinary team at Children's Hospital approached the families of 21 boys, ranging from three months old to age 14, who had been just diagnosed with various solid tumors. All faced the imminent prospect of treatments with chemotherapy or radiation that carried a significant risk of male infertility.

Of the 21 families approached, 16 consented to the biopsy as part of the research study, an acceptance rate of 76 percent. Fourteen of the 16 underwent the procedure.

In the procedure, performed at the same time the child was already under general anesthesia for standard clinical care, Thomas Kolon, M.D., a urologist at Children's Hospital, removes a small piece, about half the size of the tip of a pencil eraser, from one of the testes. Half of each specimen is frozen for potential future use. The remaining half is saved for research and analysis in Dr. Brinster's lab. In all cases, the biopsy was done safely, without any negative side effects such as excessive bleeding, pain or infection.

All of the families in the study completed a questionnaire regarding their beliefs about fertility and the factors involved in their decision whether to freeze testicular tissue. Five of the 21 families refused the biopsy, with a key factor being that they were too overwhelmed by their child's cancer diagnosis to make the decision about the testicular biopsy. In addition, a majority of the families presented with the option said having a limited time to decide about the biopsy was stressful, as they often had to decide quickly, before therapy started. Other factors, such as religion, ethics, financial considerations, and the fact that cryopreservation is currently experimental did not appear to play a major role in the parents' decision-making.

"As stressful as a child's cancer diagnosis is, many parents said they wan
'/>"/>

Contact: Rachel Salis-Silverman
Salis@email.chop.edu
267-426-6063
Children's Hospital of Philadelphia
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Stimulus grant of nearly $9 million to UC San Diego funds big study of young brains
2. Cell study explains why younger people more at risk of vCJD
3. Malaria research wins Jake Baum a Young Tall Poppy award
4. Young age at first drink may affect genes and risk for alcoholism
5. Study: Young Arctic muskoxen better at keeping warm than scientists thought
6. Technology Review names Carnegie Mellons Treuille as a top young innovator
7. Carbon nanoparticles toxic to adult fruit flies but benign to young
8. A young brain for an old bee
9. Kelvin Lee winner of Biochemical Engineering Journal Young Investigator Award
10. They are young and need the job: A second chance for dangerous T-cells
11. Promising device snags young inventors coveted spot at IShow
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... 2014  The 2014 Holiday Season may be ... Acuity Market Intelligence reports that the long anticipated ... Acuity forecasts that intensifying demand for smart phones, ... will drive a global market of 2.5 billion ... 2020.   According to Maxine ...
(Date:12/17/2014)... DUBLIN , Dec. 15, 2014 Research ... announced the addition of the "Samsung Galaxy ... Analysis" report to their offering. ... on a totally different sensing technology than the ... a fingerprint sensor in its product. ...
(Date:12/17/2014)... -- Automation is fundamentally transforming the travel experience and ... borders. Over the past decade, ePassports, biometric readers, ... to self process through border control via eGates ... increasing number of airports, seaports, and land borders ... Maxine Most , Principal at Acuity Market ...
Breaking Biology News(10 mins):First Season of Holiday Shopping with Mobile Biometric Payments Wraps Up With a Present for Biometrics Industry: A Rosy Forecast for More Than 2 Billion Users of 4.8 Billion Mobile Biometric Devices by 2020 2Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2
... this latest image acquired by ESA,s Envisat on Thursday at ... of Mexico can be seen as a dark blue swirl ... oil spill five times larger than first estimated ... threatening environmental disaster. , As efforts are being made by ...
... A team of scientists led by the Department of Energy,s ... is publishing this week the first genome sequence of an ... in a major gap among the vertebrates sequenced to date. ... far fewer other vertebrates," said co-author Richard Harland, UC Berkeley ...
... 29, 2010 The American Chemical Society Green ... its 2010 research grant to Scottish chemist David ... expanding green chemistry and engineering practices in the ... $150,000-grant to further his study of the hydrogenation ...
Cached Biology News:Oil spill in the Gulf of Mexico nears the coast 2Scientists report first genome sequence of frog 2Scientists report first genome sequence of frog 3Scientists report first genome sequence of frog 4ACS Green Chemistry Institute Pharmaceutical Roundtable award goes to Scottish chemist 2
(Date:12/22/2014)... DIEGO , Dec. 22, 2014 GenomeDx ... the Decipher Prostate Cancer Classifier, a genomic test for ... in node-negative, high-risk men managed by radical prostatectomy without ... radical prostatectomy is relatively uncommon, using tumor genomics to ... of metastatic disease is an important advance. The study ...
(Date:12/22/2014)... ITRA Global, one of the largest ... real estate, has further expanded its global reach with ... Brisbane, Western Australia, reports Mylinda Vick, CCIM, Chairman of ... Global / ACORPP (Australian Corporate Property and Projects) , ... property services to a wide range of clients in ...
(Date:12/19/2014)... MA (PRWEB) December 19, 2014 Charm ... MRLAFMQ test for the Detection of Aflatoxin M1 in ... to receive independent third party validation. The peer reviewed ... Unit of the Institute for Agricultural and Fisheries Research ... Group. , Aflatoxin B1, the most toxic aflatoxin ...
(Date:12/19/2014)... Calif. , Dec. 19, 2014  Roche (SIX: ... of Bina Technologies, Inc. (Bina), a privately held ... , USA. Bina provides a big data ... generation sequencing (NGS) data. Bina,s proprietary on-market Genomic ... and academic researchers to perform fast and scalable ...
Breaking Biology Technology:Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 2Study Published in European Urology Shows that the Decipher Prostate Cancer Classifier is Predictive of Rapid Metastasis in High-Risk Men who have had Prostate Surgery 3ITRA Global Continues International Expansion in Perth and Brisbane, Australia 2Charm Sciences Achieves Independent Validation of First 15 Minute Quantitative Screening Method for Aflatoxin M1 2Roche acquires Bina Technologies and enters the genomic informatics market 2Roche acquires Bina Technologies and enters the genomic informatics market 3
... Wis. - While human stem cells offer potential therapeutic ... more immediate benefit from research into such cells will likely ... area that for many years has been steeped in the ... since disease works within the context of cells. , ,But, ...
... La Crosse, Wis. - Healthcare professionals will have the ... implications upon the profession at the Wisconsin Dairyland HIMSS ... Sept. 12-13 at the Radisson hotel in La Crosse, will ... dedicated to social events such as a golf outing and ...
... Wis. - The Tascon Group has launched the Tascon ... analysis and job costing. , ,The Business Analyst is being ... www.thebusinessanalyst.com . , ,The program is based on a ... the 1980s - a system known as the optimization method. ...
Cached Biology Technology:Human stem cells called great opportunity for drug discovery 2Human stem cells called great opportunity for drug discovery 3Conference will review healthcare IT 2
MagSi monodispers, magnetic silica particles with modified surface for SO3 coupling chemistry....
Anti-Chicken IgY, (IgG) F(ab')2 Fragment Specific....
Rabbit polyclonal to Dishevelled 2 ( Abpromise for all tested applications). entrezGeneID: 1856 SwissProtID: O14641...
... repeat and SOCS box-containing protein) This polyclonal ... amino acids 75-93 and 348-368 of human ... No. 40149) can be used as a ... mouse and rat Asb-2, based on amino ...
Biology Products: