Navigation Links
For young boys with cancer, testicular tissue banking may be option to preserve fertility
Date:11/9/2009

f Veterinary Medicine, an internationally renowned expert in genetics and reproduction.

Starting in January 2008, a multidisciplinary team at Children's Hospital approached the families of 21 boys, ranging from three months old to age 14, who had been just diagnosed with various solid tumors. All faced the imminent prospect of treatments with chemotherapy or radiation that carried a significant risk of male infertility.

Of the 21 families approached, 16 consented to the biopsy as part of the research study, an acceptance rate of 76 percent. Fourteen of the 16 underwent the procedure.

In the procedure, performed at the same time the child was already under general anesthesia for standard clinical care, Thomas Kolon, M.D., a urologist at Children's Hospital, removes a small piece, about half the size of the tip of a pencil eraser, from one of the testes. Half of each specimen is frozen for potential future use. The remaining half is saved for research and analysis in Dr. Brinster's lab. In all cases, the biopsy was done safely, without any negative side effects such as excessive bleeding, pain or infection.

All of the families in the study completed a questionnaire regarding their beliefs about fertility and the factors involved in their decision whether to freeze testicular tissue. Five of the 21 families refused the biopsy, with a key factor being that they were too overwhelmed by their child's cancer diagnosis to make the decision about the testicular biopsy. In addition, a majority of the families presented with the option said having a limited time to decide about the biopsy was stressful, as they often had to decide quickly, before therapy started. Other factors, such as religion, ethics, financial considerations, and the fact that cryopreservation is currently experimental did not appear to play a major role in the parents' decision-making.

"As stressful as a child's cancer diagnosis is, many parents said they wan
'/>"/>

Contact: Rachel Salis-Silverman
Salis@email.chop.edu
267-426-6063
Children's Hospital of Philadelphia
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Stimulus grant of nearly $9 million to UC San Diego funds big study of young brains
2. Cell study explains why younger people more at risk of vCJD
3. Malaria research wins Jake Baum a Young Tall Poppy award
4. Young age at first drink may affect genes and risk for alcoholism
5. Study: Young Arctic muskoxen better at keeping warm than scientists thought
6. Technology Review names Carnegie Mellons Treuille as a top young innovator
7. Carbon nanoparticles toxic to adult fruit flies but benign to young
8. A young brain for an old bee
9. Kelvin Lee winner of Biochemical Engineering Journal Young Investigator Award
10. They are young and need the job: A second chance for dangerous T-cells
11. Promising device snags young inventors coveted spot at IShow
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... it the Jimmy Durante of dinosaurs a ... profile. The new dinosaur, named Rhinorex condrupus ... and Brigham Young University, lived in what is ... the Late Cretaceous period. , Rhinorex, which translates ... a close relative of other Cretaceous hadrosaurs like ...
(Date:9/19/2014)... A new resource unveiled today by researchers from ... College Dublin provides both experienced and aspiring researchers ... build, and operate robots made from soft, flexible ... printing, laser cutters, and other advances in manufacturing ... important field. Using principles drawn from conventional rigid ...
(Date:9/19/2014)... A University of Oklahoma biology professor will study the ... analysis that could eventually benefit people,s health. The ... manage the energy required to produce the signals used ... generate electric signals at a rate of 500-600 discharges ... required for the electric fish are extreme, but necessary ...
Breaking Biology News(10 mins):New hadrosaur noses into spotlight 2Soft robotics 'toolkit' features everything a robot-maker needs 2
... Researchers have discovered a potentially important new resistance factor ... team of researchers from Canadian Blood Services, The Hospital ... Sweden have discovered that certain blood types are more ... at fending it off. A carbohydrate-containing antigen, termed ...
... of painstakingly handwritten books produced in medieval Europe still ... about when and where the majority of these works ... is using modern advances in genetics to develop techniques ... important cultural artifacts. Many medieval manuscripts were written ...
... new technologies that make it easier to sequence the ... Cancer Center have identified a series of genes that ... other. These recurrent gene fusions are thought to be ... The gene fusions discovered could potentially serve as ...
Cached Biology News:Researchers identify potential new weapon in battle against HIV infection 2DNA testing may unlock secrets of medieval manuscripts 2U-M researchers discover new genes that fuse in cancer 2
(Date:9/19/2014)... Pfenex Inc. (NYSE MKT: PFNX), a clinical-stage ... difficult to manufacture proteins including biosimilar therapeutics, today announced ... Annual NewsMakers in the Biotech Industry conference in ... , chief executive officer of Pfenex, will provide an ... on Friday, September 26, 2014 at 10:00 a.m. EDT/7:00 ...
(Date:9/19/2014)... September 19, 2014 , The ... Society for Paediatric Endocrinology (ESPE) Meeting  Investment ... medical research in the field of growth  , ... Germany , today announced the first ... 2014. The awards were announced during a Satellite Symposium ...
(Date:9/18/2014)... 2014 /PRNewswire-iReach/ -- DeepResearchReports.com adds "2014 Deep Research ... and "2014 Deep Research Report on Global and ... database. Photo - http://photos.prnewswire.com/prnh/20140918/147058 ... Global and China Acetic Acid Industry" is a ... China and Global Acetic Acid Market. ...
(Date:9/18/2014)... 18, 2014 On Tuesday, Secretary of ... Jim Risch for National Lab Day on the Hill. ... the national laboratory system. Durbin and Risch also formally ... increase awareness of the reach of the national labs ... to address some of our nation's most pressing challenges. ...
Breaking Biology Technology:Pfenex to Present at Upcoming Industry Conference on September 26 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 2Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 4Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 2Lab Day Highlight Labs' Contribution to U.S. Competitiveness and Innovation 3
... Sponsors 2010 Semantic Web Challenge -- NEW YORK, November 16, 2010 ... ... if (typeof(lpUnit)==,undefined,) var lpUnit=,PRN,; --> ... = function(data) { var s = ,; var first_result; // Results are keyed by longUrl, so we need to ...
... London, involves a new class of materials called metamaterials, ... sound waves. With conventional materials, light typically travels along ... a wealth of additional flexibility to create undetectable blind ... an image can be altered or made to look ...
... 15, 2010, PRNewswire-Asia/ -- Tiens Biotech Group (USA), Inc. (the "Company" ... , today announced financial results for ... Revenue for the third quarter of 2010 was $10.4 million, ... for the nine months ended September 30, 2010 was $30.0 million, ...
Cached Biology Technology:Elsevier Sponsors 2010 Semantic Web Challenge 2Elsevier Sponsors 2010 Semantic Web Challenge 3Elsevier Sponsors 2010 Semantic Web Challenge 4Elsevier Sponsors 2010 Semantic Web Challenge 5Elsevier Sponsors 2010 Semantic Web Challenge 6Elsevier Sponsors 2010 Semantic Web Challenge 7Elsevier Sponsors 2010 Semantic Web Challenge 8Elsevier Sponsors 2010 Semantic Web Challenge 9Elsevier Sponsors 2010 Semantic Web Challenge 10Elsevier Sponsors 2010 Semantic Web Challenge 11'Space-time cloak' to conceal events revealed in new study 2'Space-time cloak' to conceal events revealed in new study 3Tiens Biotech Group (USA) Reports Third Quarter and Nine-Month Results 2Tiens Biotech Group (USA) Reports Third Quarter and Nine-Month Results 3Tiens Biotech Group (USA) Reports Third Quarter and Nine-Month Results 4Tiens Biotech Group (USA) Reports Third Quarter and Nine-Month Results 5Tiens Biotech Group (USA) Reports Third Quarter and Nine-Month Results 6Tiens Biotech Group (USA) Reports Third Quarter and Nine-Month Results 7Tiens Biotech Group (USA) Reports Third Quarter and Nine-Month Results 8Tiens Biotech Group (USA) Reports Third Quarter and Nine-Month Results 9
MOUSE ANTI PROTEIN KINASE C BETA 2 Immunogen: Protein kinase C beta 2...
Antibodies were affinity purified using epitopes specific to JLP immobilized on solid support....
... et.al. (1997) • Contains short ... biochemistry & molecular biology, arranged ... Entries give details of biochemical ... which they are involved and ...
...
Biology Products: