"Working together, our research network has the extraordinary opportunity to investigate novel methods for cardiac regeneration to repair injured hearts," says Dr. Hajjar, who also serves as the Arthur & Janet C. Ross Professor of Medicine and Professor of Gene & Cell at Mount Sinai. "Our ultimate mission is to advance this emerging translational medicine field with discovery and the rapid translation of novel cardiac regenerative therapies from the laboratory bench to the patient's clinic for testing in innovative clinical trials."
Currently, there is no scientific consensus on what process governs or restricts cardiac regeneration. The research network hopes to gain a greater comprehensive understanding of the roles played by cardiac stem cells, heart muscle cells known as cardiomyocytes, and other cardiac cell types that regulate cardiac regeneration to assess their potential capabilities to assist in the revival and regeneration of a damaged heart and its tissues for patients diagnosed with impaired cardiac function or structural damage.
As of 2013, Fondation Leducq has supported 39 research networks, more than 360 investigators at 123 institutions in 18 countries. The Fondation Leducq was created in 1996 by Jean and Sylviane Leducq to support collaborative work between investigators in North America and Europe. The Transatlantic Networks of Excellence Research Program was launched in 2003.
The Cardiovascular Research Center at Mount Sinai directed by Dr. Hajjar was founded in 2007. It conducts cross-disciplinary basic and translational cardiovascular research to prevent and reverse heart disease, heart failure, and atherosclerosis which is the hardening of the heart's arteries due to plaque buildup a leading cause of heart attack, stroke, and peripheral vascular disease. The Center's research investigations focus on cardiovascular disease, heart failure, vasc
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The Mount Sinai Hospital / Mount Sinai School of Medicine