Navigation Links
Fondation Leducq awards $6 million grant for global research network for cardiac regeneration
Date:7/1/2013

The Fondation Leducq in Paris, France, dedicated to improving human health through international efforts to combat cardiovascular disease, awarded a $6 million grant award to a new global research network of cardiovascular scientists which includes three researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

This new large grant was awarded as part of the Fondation Leducq's Transatlantic Networks of Excellence in Cardiovascular Research Program. Network researchers will aim to identify cellular and molecular targets to help advance cardiac regeneration therapeutics. Their research proposal was one of only four research projects selected this year for funding by the foundation from among one hundred applications. Research is planned to launch in January 2014.

The new global network brings together physician-scientists with leading expertise in developmental biology, cardiac stem cell biology, biomarkers, gene therapy, metabolism, immunology, pharmacogenomics, and clinical cardiology.

The new research network includes Mount Sinai's Roger Hajjar, MD, Director of the Cardiovascular Research Center at Mount Sinai, Jean-Sebastien Hulot, MD, PhD, Director of Pharmacogenomics and Personalized Therapeutics at the Cardiovascular Research Center at Mount Sinai, and Jason Kovacic, MD, PhD, Assistant Professor of Medicine in Cardiology at Mount Sinai. Other network members include: Toren Finkel, MD, PhD, of the National Institutes of Health, the North American Coordinator; David Sassoon, PhD, of the Universite de Pierre et Marie Curie-Sorbonne Universites in Paris, France, the European Coordinator; Thomas Braun, MD, PhD, of Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany; Richard Harvey, PhD, of Victor Chang Cardiac Research Institute, Sydney, Australia; Nadia Rosenthal, PhD, of the National Heart and Lung Institute, Imperial College in London, UK; and Mark Sussman, PhD, of San Diego State University, SDSU Heart Institute, in San Diego, CA.

"Working together, our research network has the extraordinary opportunity to investigate novel methods for cardiac regeneration to repair injured hearts," says Dr. Hajjar, who also serves as the Arthur & Janet C. Ross Professor of Medicine and Professor of Gene & Cell at Mount Sinai. "Our ultimate mission is to advance this emerging translational medicine field with discovery and the rapid translation of novel cardiac regenerative therapies from the laboratory bench to the patient's clinic for testing in innovative clinical trials."

Currently, there is no scientific consensus on what process governs or restricts cardiac regeneration. The research network hopes to gain a greater comprehensive understanding of the roles played by cardiac stem cells, heart muscle cells known as cardiomyocytes, and other cardiac cell types that regulate cardiac regeneration to assess their potential capabilities to assist in the revival and regeneration of a damaged heart and its tissues for patients diagnosed with impaired cardiac function or structural damage.

As of 2013, Fondation Leducq has supported 39 research networks, more than 360 investigators at 123 institutions in 18 countries. The Fondation Leducq was created in 1996 by Jean and Sylviane Leducq to support collaborative work between investigators in North America and Europe. The Transatlantic Networks of Excellence Research Program was launched in 2003.

The Cardiovascular Research Center at Mount Sinai directed by Dr. Hajjar was founded in 2007. It conducts cross-disciplinary basic and translational cardiovascular research to prevent and reverse heart disease, heart failure, and atherosclerosis which is the hardening of the heart's arteries due to plaque buildup a leading cause of heart attack, stroke, and peripheral vascular disease. The Center's research investigations focus on cardiovascular disease, heart failure, vascular disease, heart valve problems, and ventricular dysfunction.

"Cardiovascular disease is the leading cause of death around the world. New global research alliances like ours, thanks to the generous support of the Fondation Leducq, will truly accelerate the development of more refined therapies to ease the wide-reaching burden of cardiovascular disease," says Dr. Hajjar.


'/>"/>

Contact: Lauren Woods
lauren.woods@mountsinai.org
212-241-2836
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

Related biology news :

1. MARC travel awards announced for the AAI 2013 Advanced Course in Immunology Meeting
2. MARC travel awards announced for the GSA: 19th International C. elegans Meeting
3. MARC travel awards announced for the 27th Protein Society Symposium 2013
4. MARC travel awards announced for the July 2013 FASEB Science Research Conferences
5. MARC travel awards announced for the AAI 2013 Introductory Course in Immunology Meeting
6. MARC travel awards announced for the 2013 Society for the Study of Reproduction Meeting
7. MARC travel awards announced for the June 2013 FASEB science research conferences
8. 2013 World Cultural Council awards
9. NIH awards UCI $10 million to study early-life origins of adolescent mental disorders
10. U-M Water Center awards $570K in Great Lakes restoration grants
11. MARC Travel Awards announced for the ENDO 2013 95th Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2017)... 23, 2017  Hunova, the first robotic gym for the rehabilitation and ... launched in Genoa, Italy . The first 30 robots ... the USA . The technology was developed and patented ... the IIT spin-off Movendo Technology thanks to a 10 million euro investment ... please click: ...
(Date:4/19/2017)... , April 19, 2017 ... its vendor landscape is marked by the presence of ... is however held by five major players - 3M ... these companies accounted for nearly 61% of the global ... leading companies in the global military biometrics market boast ...
(Date:4/11/2017)... BEACH GARDENS, Fla. , April 11, 2017 ... identity management and secure authentication solutions, today announced ... contract by Intelligence Advanced Research Projects Activity (IARPA) ... for IARPA,s Thor program. "Innovation has ... onset and IARPA,s Thor program will allow us ...
Breaking Biology News(10 mins):
(Date:10/12/2017)... ... October 12, 2017 , ... ... States multicenter, prospective clinical study that demonstrates the accuracy of the FebriDx® ... identifying clinically significant acute bacterial and viral respiratory tract infections by testing ...
(Date:10/11/2017)... N.C. (PRWEB) , ... October 11, 2017 , ... ... ARCS® Foundation President Andi Purple announced Dr. Suneel I. Sheikh, the co-founder, ... ( ASTER Labs ), Inc. has been selected for membership in ARCS ...
(Date:10/11/2017)... BALTIMORE, Md. (PRWEB) , ... October 11, 2017 ... ... for digital pathology, announced today it will be hosting a Webinar titled, “Pathology ... of  Advanced Pathology Associates , on digital pathology adoption best practices and how ...
(Date:10/11/2017)... ... October 11, 2017 , ... A ... pregnancy rates in frozen and fresh in vitro fertilization (IVF) transfer ... age to IVF success. , After comparing the results from the fresh and ...
Breaking Biology Technology: