Navigation Links
Follow that cell
Date:8/15/2014

The National Institutes of Health is challenging science innovators to compete for prizes totaling up to $500,000, by developing new ways to track the health status of a single cell in complex tissue over time. The NIH Follow that Cell Challenge seeks tools that would, for example, monitor a cell in the process of becoming cancerous, detect changes due to a disease-causing virus, or track how a cell responds to treatment.

"Advances in cellular analysis promise earlier diagnosis and improved therapies for diseases, from cancer to Alzheimer's," said James Anderson, M.D., Ph.D., director of NIH's Division of Program Coordination, Planning, and Strategic Initiatives (DPCPSI). "These prizes will also help to stimulate new businesses and economic growth in our biomedical communities."

The challenge aims to generate creative ideas and methods for following and predicting a single cell's behavior and function over time in a complex multicellular environment preferably using multiple integrated measures to detect its changing state.

The challenge is issued under America COMPETES, by the National Institute of Mental Health (NIMH) and National Institute of Biomedical Imaging and Bioengineering (NIBIB), on behalf of the NIH Common Fund's Single Cell Analysis Program (SCAP), part of DPCPSI.

"All cells of a particular type are not identical," explained Anderson. "An individual cell may become very different, affecting the health and function of its entire population. Today's tools provide mostly snapshots of single cells, not the movie of changes over time that we need to understand cell states and transitions from one state to another."

Although several grant-supported studies exploring these issues are underway, SCAP sought to stimulate efforts beyond academia among a more diverse community than researchers who typically apply for NIH grants. These include innovators and problem solvers from U.S. industry research and development and even from fields outside of biomedicine.

Phase 1 of the challenge, which begins today, seeks theoretical, written solutions, due by Dec. 15, 2014. Submissions will be screened by panels of outside and NIH staff experts prior to review by a three-judge panel consisting of the NIMH, NIBIB, and DPCPSI directors, who will award up to six prizes totaling $100,000, to be announced March 16, 2015.

Phase 1 winners and runners-up will be eligible to participate in Phase 2, a "Reduction to Practice" to provide proof of concept data related to their Phase 1 entries. These submissions will be due March 30, 2017. One or two winning solutions will receive prizes totaling $400,000, to be announced July 31, 2017.

Details of the criteria by which entries will be evaluated were published in the Federal Register Aug. 11, 2014. A registration link for the Challenge is available on the SCAP Challenge page and on the Follow That Cell website maintained by InnoCentive, Inc., which is hosting and marketing the challenge under contract with NIH. While only citizens or permanent residents of the United States are eligible to compete individually as solvers, non-citizens may participate as a member of a team.

"We believe that combining the immense brainpower of scientists, engineers and innovators will propel the development of the next generation of single cell analysis, galvanizing this field," said Anderson.


'/>"/>

Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health
Source:Eurekalert  

Related biology news :

1. Protein evolution follows a modular principle
2. Mode of delivery following a perineal tear and recurrence rate in subsequent pregnancies
3. Pregnancies following egg donation associated with more than 3-fold higher risk of hypertension
4. Body odor changes following vaccination
5. Gastric banding patients should closely monitor nutrition following surgery
6. Harvard scientists control cells following transplantation, from the inside out
7. MU research sheds light on nerve regeneration following spinal cord injury
8. Can Aβ worsen cognitive impairment following cerebral ischemia-reperfusion injury?
9. Mycobacterium tuberculosis: Our African follower for over 70,000 years!
10. First child born following embryo screening with new genome analysis technique
11. Lifesaving HIV treatment could reach millions more people following landmark study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Follow that cell
(Date:11/30/2016)... , Nov. 30, 2016 Not many of us realize that we ... of recovery so we need to do it well. Inadequate sleep levels have been ... blood pressure, stroke, diabetes, and even cancer. Maybe now is the best ... that could help them to manage their sleep quality? ... ...
(Date:11/29/2016)... , Nov. 29, 2016   ... identification and object recognition technologies, today released ... for fingerprint recognition solutions that run on ... fingerprint template using less than 128KB of ... compact devices that have limited on-board resources, ...
(Date:11/24/2016)... Cercacor today introduced Ember TM Sport ... non-invasively measure hemoglobin, Oxygen Content, Oxygen Saturation, Perfusion ... in approximately 30 seconds. Smaller than a smartphone, using ... to key data about their bodies to help monitor ... Hemoglobin carries oxygen to muscles. When hemoglobin ...
Breaking Biology News(10 mins):
(Date:12/2/2016)... CytRx Corporation (NASDAQ: CYTR ), ... today announced the appointment of Earl Warren Brien ... private healthcare investor, to its Board of Directors. ... and strategic experience at the highest level," said ... one of the world,s leading orthopedic surgeons, Dr. Brien ...
(Date:12/2/2016)... ... December 01, 2016 , ... ... the value of DNA microarray comparative genomic hybridization (array CGH) for HER2 ... Cancer Symposium. Using molecular test results from tumors with previously documented positive, ...
(Date:12/2/2016)... ... , ... The Conference Forum has announced that the 3rd annual Immuno-Oncology ... February 1-3, 2017 at the Roosevelt Hotel in New York City. Led by advisors ... 360-degree approach, which addresses the most up-to-date information regarding business aspects, clinical advancements and ...
(Date:12/2/2016)... , ... December 02, 2016 ... ... a consortium of pharmaceutical and biotechnology companies dedicated to collaboratively developing improved ... interested in supplying a vendor-supported, portable online UHPLC, with robust, probe-based sampling. ...
Breaking Biology Technology: