Navigation Links
Folic acid lowers risk of autism
Date:3/11/2013

These findings are the result of a new study carried out at the Norwegian Institute of Public Health. In the study, women who took folic acid supplements from four weeks before conception to eight weeks into pregnancy had a 40 per cent lower risk of giving birth to children with childhood autism (classic autism).

"It appears that the crucial time interval is from four weeks before conception to eight weeks into pregnancy," states Pl Surn, MD and doctoral fellow at the Norwegian Institute of Public Health.

The study is based on the Norwegian Mother and Child Cohort Study (MoBa) and the Norway Autism Birth Cohort Study (ABC). It covered a total of 85 176 children born in the period 2002.

Inexpensive, simple prevention

Folic acid is a B vitamin that is essential for the construction and repair of DNA molecules, which control all body cells. Folate is the naturally occurring form of folic acid found in food and in the body.

Most pregnant women need folic acid supplements to reach the daily recommended levels. The Norwegian Directorate of Health recommends that women who are planning to become pregnant start to take folic acid supplements one month before conception and during the first three months of pregnancy.

The results of the study of the correlation between intake of folic acid supplements and childhood autism indicate that the lower risk is only associated with this specific supplement and not with the consumption of food or other supplements.

"Thus, the findings show that a measure already used here in Norway, one which is simple, inexpensive and without any known side effects among pregnant women, can prevent autism. Previous studies we have carried out have shown that folic acid may have a similar effect on other developmental disorders as well," Dr Surn says.

Important in other areas as well

The Directorate of Health's recommendations regarding pre-natal folic acid supplements are based on research that shows that the vitamin protects the foetus against spina bifida and other neural tube defects.

The researchers have also found a correlation between folic acid supplements and the reduced risk of severe language delay by the age of three. Such language problems are common in connection with autism but may also occur with many other conditions.

"It will be a tremendous breakthrough if it turns out that folic acid also prevents other developmental disorders," Dr Surn believes.

Some more vulnerable than others?

Dr Surn and his colleagues will conduct new analyses when the children involved in the study are older, among other things to examine whether there is any correlation between folic acid and a reduced risk of other developmental disorders such as ADHD and cerebral palsy. They will also carry out genetics studies.

"We know that there is a genetic component to the body's ability to use folate, so it is possible that some mothers are more prone to folic acid deficiency than others," Dr Surn adds.


'/>"/>
Contact: Thomas Keilman
thke@rcn.no
The Research Council of Norway
Source:Eurekalert

Related biology news :

1. Coalition petitions FDA to fortify corn masa flour with folic acid
2. Folic acid food enrichment potentially protective against childhood cancers
3. Lack of key enzyme in the metabolism of folic acid leads to birth defects
4. New research lowers past estimates of sea-level rise
5. Scientists discover switch in plants to create flowers
6. Omega-3 lowers inflammation in overweight older adults
7. High-speed video and artificial flowers shed light on mysteries of hummingbird-pollinated flowers
8. Insect-eating bat outperforms nectar specialist as pollinator of cactus flowers
9. In the Eastern US, spring flowers keep pace with warming climate
10. Dont be fooled: Flowers mislead traditional taxonomy
11. Holding a mirror to brain changes in autism
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)...   The Weather Company , an IBM Business (NYSE: ... capability in which consumers will be able to interact with ... via voice or text and receive relevant information about the ... Marketers have long sought an advertising solution that can create ... relevant and valuable; and can scale across millions of interactions ...
(Date:5/16/2016)... YORK , May 16, 2016   EyeLock ... solutions, today announced the opening of an IoT Center ... to strengthen and expand the development of embedded iris ... an unprecedented level of convenience and security with unmatched ... authenticate one,s identity aside from DNA. EyeLock,s platform uses ...
(Date:4/28/2016)... First quarter 2016:   , ... the first quarter of 2015 The gross margin was ... 18.8) and the operating margin was 40% (-13) Earnings ... flow from operations was SEK 249.9 M (21.2) , ... SEK 7,000-8,500 M. The operating margin for 2016 is ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... 23, 2016 /PRNewswire/ - FACIT has announced the ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or ... of a portfolio of first-in-class WDR5 inhibitors for ... as WDR5 represent an exciting class of therapies, ... medicine for cancer patients. Substantial advances have been ...
(Date:6/23/2016)... , June 23, 2016 Houston ... with the Cy-Fair Sports Association to serve as ... the agreement, Houston Methodist Willowbrook will provide sponsorship ... and connectivity with association coaches, volunteers, athletes and ... with the Cy-Fair Sports Association and to bring ...
(Date:6/23/2016)... June 23, 2016  The Prostate Cancer Foundation (PCF) is pleased ... and faster cures for prostate cancer. Members of the Class of 2016 were ... Read More About the Class of 2016 PCF Young ... ... ...
(Date:6/23/2016)...   EpiBiome , a precision microbiome engineering company, ... financing from Silicon Valley Bank (SVB). The financing will ... its drug development efforts, as well as purchase additional ... has been an incredible strategic partner to us – ... would provide," said Dr. Aeron Tynes Hammack , ...
Breaking Biology Technology: