Navigation Links
Folate intake may reduce colorectal cancer risk
Date:7/5/2011

A new study finds high folate intake is associated with a reduced risk of colorectal cancer, a finding consistent with the findings of most previous epidemiologic studies. The study is reassuring, as previous recent evidence has suggested that consumption of very high levels of folate through supplements and from folate-fortified diet may increase risk of some cancers. Nonetheless, the potential importance of folate in colorectal cancer prevention remains in question because at least one other study found folate supplementation had no effect on recurrence of colorectal adenomas, precursors to colorectal cancer.

The study appears in Gastroenterology, and is the first to look at the association of folate with colorectal cancer risk with follow-up entirely after the mandatory fortification of the U.S. diet with folate. It also is the first to distinguish between the forms of folate found naturally in forms and folic acid, the form used for fortification and in supplements.

A research team led by Victoria Stevens, Ph.D., strategic director of laboratory services at the American Cancer Society, investigated the association between folate intake and colorectal cancer among 99,523 participants in the Cancer Prevention Study II Nutrition Cohort. A total of 1,023 participants were diagnosed with colorectal cancer between 1999 and 2007, a period entirely after folate fortification began. Neither higher nor lower risk was observed during the first two years of follow-up (1999 to 2001), but during 2002 to 2007, high folate intake was associated with a reduced risk of colorectal cancer.

"While folate fortification has been a public health success in reducing the risk of neural tube defects, the potential for an increase risk of cancer has been legitimate," said Dr. Stevens. "Our study population included many participants who consumed these very high levels of folate and we found no increased risk of colorectal cancer in these individuals.
'/>"/>

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society
Source:Eurekalert

Page: 1 2

Related biology news :

1. High red blood cell folate levels linked to silenced tumor-suppressors
2. Age-related hearing loss and folate in the elderly
3. Folate prevents alcohol-induced congenital heart defects in mice
4. Attention-deficit/hyperactivity problems associated with low folate levels in pregnant women
5. SNPs affect folate metabolism in study of Puerto-Rican adults
6. Rigorous study confirms video game playing increases food intake in teens
7. Genetic variants associated with caffeine intake identified
8. Maternal fructose intake impacts female and male fetuses differently
9. Moderate-to-heavy alcohol intake may increase risk of atrial fibrillation
10. Extensive research demonstrates fructose does not increase food intake or impact weight
11. Pattern of drinking affects the relation of alcohol intake to coronary heart disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... study (HPV-023; NCT00518336) shows the sustained efficacy, ... virus (HPV) vaccine Cervarix. Women vaccinated with ... more than nine years, and vaccine efficacy ... is the longest follow-up report for a ... for the full paper. , HPV ...
(Date:7/31/2014)... 100 percent of animal models against the highly infectious ... an intestinal disease that kills approximately 30,000 Americans annually. ... Infection and Immunity . , In the study, ... the purified toxins produced by C. difficile , ... laboratory model that mimics the human disease, after only ...
(Date:7/31/2014)... that the U.S. surgeon general issued a 101-page report ... State University published a paper breaking new ground on ... responds when exposed to ultraviolet (UV) light. , ... the UV rays found in sunlight. This damage can ... diseases. , "Our paper advances foundational knowledge about ...
Breaking Biology News(10 mins):Sustained efficacy, immunogenicity, and safety for GlaxoSmithKline's HPV vaccine 2Sustained efficacy, immunogenicity, and safety for GlaxoSmithKline's HPV vaccine 3C. difficile vaccine proves safe, 100 percent effective in animal models 2New paper describes how DNA avoids damage from UV light 2New paper describes how DNA avoids damage from UV light 3
... Hold the Key to Muscular Dystrophy , A mutation ... been known to be associated with muscular dystrophy, but ... unknown. Lorenzo Puri, M.D., Ph.D. and colleagues have discovered ... amount of the histone deacetylase enzyme, HDAC2. Increased HDAC2 ...
... ever wondered why it seems like the littlest things make ... a spilled glass of water can lead to a fist ... three words to explain why people may be evolutionarily inclined ... sex. Although hostility or belligerent acts might not immediately ...
... long known that dinosaurs had tiny brains, but they had ... new study by Ohio University researchers Lawrence Witmer and Ryan ... heads than expected. By using CT scans, the scientists were ... show a clearer picture of the physiology of the airways. ...
Cached Biology News:The Burnham buzz 2U of Minnesota researcher finds link between aggression, status and sex 2CT scans reveal that dinosaurs were airheads 2CT scans reveal that dinosaurs were airheads 3
(Date:7/31/2014)... 2014 Nearly 20,000 medical professionals and healthcare ... & Clinical Lab Expo in Chicago ... in diagnostic research and technology that will advance medicine ... As of Wednesday, July 30, more than 19,500 attendees ... Clinical Lab Expo, with more than 10,000 of these ...
(Date:7/31/2014)... the sound-processing part of the mouse brain in a ... trees in view. Their imaging technique allows zooming in ... and it enabled the team to watch brain cells ... results, which represent a step toward better understanding how ... the journal Neuron . , In the past, ...
(Date:7/31/2014)... , July 31, 2014 Rogne Bioscience, a ... Bay Area , has acquired a licence to ... commercialisation company. The potent anti-inflammatory activity of the peptides ... the University of Oxford,s Sir William Dunn School ... has raised over $1.5 million in seed financing, is ...
(Date:7/31/2014)... July 31, 2014 Research and Markets ... Genomics Market 2014-2018" report to their offering. ... is the study of the genetic material or genomes ... strong basis for the discovery and development of diagnostic ... or health conditions. Genomics is supported by three major ...
Breaking Biology Technology:Research on Digital Health, Alzheimer's, Ebola Draws Nearly 20,000 Attendees to 2014 AACC Annual Meeting & Clinical Lab Expo 2Research on Digital Health, Alzheimer's, Ebola Draws Nearly 20,000 Attendees to 2014 AACC Annual Meeting & Clinical Lab Expo 3New mapping approach lets scientists zoom in and out as the brain processes sound 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 3Global Genomics Market 2014-2018: Key Vendors are F. Hoffmann-La Roche, Life Technologies, Qiagen and Illumina 2
... Biosciences,Corporation (Nasdaq: MATK ) today announced that ... Wilmington, Delaware, has ruled on various,post-trial motions and ... the defendants in the patent infringement suit brought ... Nutrition Specialties &,Food Ingredients GmbH. The suit involves ...
... Nov. 1 ThermoGenesis,Corp. (Nasdaq: KOOL ), a ... store, and administer therapeutic doses of,adult stem cells for ... financial results for the fiscal first quarter ended September,30, ... Call and Webcast Management will host a conference ...
... technical feasibility of ... ... TSX symbol: SBS, CALGARY, Nov. 1 /PRNewswire-FirstCall/ - ... for metabolic and cardiovascular diseases, today announced its,2007 third quarter operational ...
Cached Biology Technology:Martek to Obtain Permanent Injunction Against Lonza in U.S. Patent Infringement Suit; Jury Verdict on Infringement of Two of Three Patents Upheld by Judge 2Martek to Obtain Permanent Injunction Against Lonza in U.S. Patent Infringement Suit; Jury Verdict on Infringement of Two of Three Patents Upheld by Judge 3ThermoGenesis Corp. to Announce First Quarter Fiscal 2008 Results on November 8, 2007 2ThermoGenesis Corp. to Announce First Quarter Fiscal 2008 Results on November 8, 2007 3SemBioSys announces 2007 third quarter results 2SemBioSys announces 2007 third quarter results 3SemBioSys announces 2007 third quarter results 4SemBioSys announces 2007 third quarter results 5SemBioSys announces 2007 third quarter results 6SemBioSys announces 2007 third quarter results 7SemBioSys announces 2007 third quarter results 8SemBioSys announces 2007 third quarter results 9SemBioSys announces 2007 third quarter results 10SemBioSys announces 2007 third quarter results 11SemBioSys announces 2007 third quarter results 12
More cell-permeant than acridine orange....
HistoScan HRP Kit Universal Goat Kit...
4',6-Diamidino-2-phenylindole dihydrochloride...
...
Biology Products: