Navigation Links
Fluorescent nano-barcodes could revolutionize diagnostics
Date:5/22/2008

A new technology with research and clinical application including the early detection of disease has been invented and developed by University of Queensland researchers.

Dr Krassen Dimitrov, from UQ's Australian Institute for Bioengineering & Nanotechnology, has developed fluorescent barcodes called nanostrings, offers greater sensitivity and accuracy than current detection methods.

The research has been published the prestigious international journal Nature Biotechnology.

Dr Dimitrov said nanostrings bind to RNA molecules for digital gene expression analysis.

Because this system can count the exact number of biomolecules present we can get an extremely accurate and sensitive picture of gene expression at a particular point in time, Dr Dimitrov said.

This quantitative data is superior to other gene expression systems such as microarrays, which rely on the analogue measurement of fluorescence and therefore are less accurate and have a limited range.

The nanostring is an important technological development in both clinical and research settings. We will be able to more accurately detect molecules associated with particular diseases and in the research arena, we will be able to identify new molecules associated with diseases and trace these back to the genes responsible."

He said the technology is based on a non-enzymatic process which reduces the chance of bias and is more robust in a variety of different conditions.

Dr Dimitrov is currently working on the next step, which will be new nano-barcodes that will further reduce the cost and improve sensitivity and usability.


'/>"/>

Contact: Dr. Krassen Dimitrov
k.dimitrov@uq.edu.au
61-733-463-880
Research Australia
Source:Eurekalert

Page: 1

Related biology news :

1. Carnegie Mellon scientists develop fluorescent proteins for live cell imaging, biosensor design
2. Fluorescent cells give early warning for eye disease
3. Newly created cancer stem cells could aid breast cancer research
4. Obesity and lack of exercise could enhance the risk of pancreatic cancer
5. Finding that 1-in-a-billion that could lead to disease
6. 60 second test could help early diagnosis of common brain diseases
7. Auto immune response creates barrier to fertility; could be a step in speciation
8. Paracetamol, one of most used analgesics, could slow down bone growth
9. Drug could improve pregnancy outcomes in wider range of women with insulin resistance
10. Thousands of starving children could be restored to health with peanut butter program
11. Nanotech could make solar energy as easy and cheap as growing grass
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2016)... , April 27, 2016 ... "Global Multi-modal Biometrics Market 2016-2020"  report to their ... , The analysts forecast the global ... of 15.49% during the period 2016-2020.  ... of sectors such as the healthcare, BFSI, transportation, ...
(Date:4/13/2016)... April 13, 2016  IMPOWER physicians supporting Medicaid patients ... a new clinical standard in telehealth thanks to a ... the higi platform, IMPOWER patients can routinely track key ... body mass index, and, when they opt in, share ... visit to a local retail location at no cost. ...
(Date:3/22/2016)... , March 22, 2016 ... report "Electronic Sensors Market for Consumer Industry by Type ... Others), Application (Communication & IT, Entertainment, Home ... Global Forecast to 2022", published by MarketsandMarkets, ... expected to reach USD 26.76 Billion by ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... June 27, 2016  Sequenom, Inc. (NASDAQ: ... healthier lives through the development of innovative products and ... the United States denied its petition ... claims of Sequenom,s U.S. Patent No. 6,258,540 (",540 Patent") ... established by the Supreme Court,s Mayo Collaborative Services v. ...
(Date:6/27/2016)... June 27, 2016  Liquid Biotech ... funding of a Sponsored Research Agreement with The ... cells (CTCs) from cancer patients.  The funding will ... levels correlate with clinical outcomes in cancer patients ... will then be employed to support the design ...
(Date:6/24/2016)... ... June 24, 2016 , ... Researchers at the Universita Politecnica delle Marche in ... peritoneal or pleural mesothelioma. Their findings are the subject of a new article on ... biomarkers are signposts in the blood, lung fluid or tissue of mesothelioma patients that ...
(Date:6/23/2016)... 23, 2016 A person commits a crime, and ... to track the criminal down. An outbreak of ... Drug Administration (FDA) uses DNA evidence to track down the ... Sound far-fetched? It,s not. The FDA has increasingly used a ... of foodborne illnesses. Put as simply as possible, whole genome ...
Breaking Biology Technology: