Navigation Links
Fluorescence monitoring and effect of photodynamic therapy for port wine stains
Date:3/1/2010

This release is available in Chinese.

It is known that fluctuations in the treatment outcome of photodynamic therapy (PDT) between patients are related to the concentration of photosensitizer in target tissue. The purpose of a study, by Wang et al, published in the February 2010 issue of Experimental Biology and Medicine was to establish a fluorescence method not only providing a semi-quantitative measurement of photosensitizer concentration but also predicting the efficacy of PDT for Port Wine Stains (PWS).

This work was conducted by Ying Wang and Xiaohua Liao when they were postgraduate students under the direction of Professor Ying Gu and Professor Rong Chen, and colleagues in the Department of Laser Medicine at the Chinese People's Liberation Army General Hospital. Currently, Ying Wang is a physician at Chinese PLA General Hospital, Xiaohua Liao works at Fujian Metrology Institute. An algorithm which can yield a semi-quantitative measurement of photosensitizer concentration was established in this study. Then a therapeutic effect correlation index (TECI) was proposed as the area under the photosensitizer concentration-time curve during PDT. The correlation between TECI and PDT treatment outcome was analyzed from 31 PWS patients at the Chinese People's Liberation Army General Hospital.

Dr. Wang noted that "A non-invasive fluorescence method that can monitor photosensitizer concentration during PDT for PWS was established, and a therapeutic effect correlation index (TECI) was verified to be positively correlated with PDT outcome for the first time in this paper."

Dr. Steven R. Goodman, Editor-in-Chief of Experimental Biology and Medicine said "The results of the study by Wang et al suggest that fluorescence spectroscopy can be used in situ to monitor skin photosensitizer concentration during PDT. This may provide a valuable diagnostic tool to predict PDT outcome."


'/>"/>

Contact: Dr. Ying Gu
guyinglaser@sina.com
Society for Experimental Biology and Medicine
Source:Eurekalert

Related biology news :

1. Novel technique for fluorescence tomography of tumors in living animals
2. Pitt researchers use fluorescence to develop method for detecting mercury in fish
3. Laser fluorescence could find life on Mars
4. Scripps scientists discover fluorescence in key marine creature
5. Volcano monitoring will target hazard threat to Marianas, US military and commercial jets
6. ACS webinar features developments in online water and wastewater monitoring
7. Listen to the natives for better moose monitoring
8. New Fujitsu UHF RFID Technology Implemented at Fairmont Pacific Rim Hotel for Advanced Inventory Monitoring
9. Breakthrough in monitoring tropical deforestation announced in Copenhagen
10. Ecologists sound out new solution for monitoring cryptic species
11. New beryllium reference material for occupational safety monitoring
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/18/2016)... 2016  Extenua Inc., a pioneering developer of ... and access of ubiquitous on-premise and cloud storage, today ... Cyber.  ... C4ISR and Cyber initiatives in support of National ... technology solutions," said Steve Visconti , Extenua ...
(Date:1/11/2016)... 2016 Synaptics Incorporated (NASDAQ: SYNA ), ... that its ClearPad ® TouchView ™ 4300 ... separate categories in the 8 th Annual Mobile ... Breakthrough. The Synaptics ® TDDI solution enables faster ... thinner devices, brighter displays and borderless designs. ...
(Date:1/7/2016)... , Jan. 7, 2016 This BCC Research ... for biometric technologies and devices, identifying newer markets and ... various types of biometric devices. Includes forecast from 2015 ... Identify newer markets and explore the expansion of the ... Examine each type of biometric technology, determine its current ...
Breaking Biology News(10 mins):
(Date:2/4/2016)... ... February 04, 2016 , ... Morf ... today announced an interactive FDA compliance training course, Writing Effective ... Professional Society) accredited interactive course on Morf Playbook—now conveniently available on smartphones and ...
(Date:2/4/2016)... ... February 04, 2016 , ... ... and triple quad LC-MS, host live demos and poster sessions, and present on ... exhibition. The conference takes place March 6 to 10 at the Georgia World ...
(Date:2/4/2016)... MONMOUTH JUNCTION, N.J. , Feb. 4, 2016 ... critical care immunotherapy leader commercializing its flagship CytoSorb® ... and cardiac surgery patients around the world, announced ... PhD, will present at the Source Capital Group,s ... overview and update on the company.  ...
(Date:2/4/2016)... 4, 2016 ContraVir Pharmaceuticals, Inc. (NASDAQ: ... and commercialization of targeted antiviral therapies, announced today that ... 2016, to be held February 8-9, 2016, at the ... Disruptive Growth & Healthcare Conference, taking place in ... James Sapirstein , Chief Executive Officer of ...
Breaking Biology Technology: