Navigation Links
Fluorescence monitoring and effect of photodynamic therapy for port wine stains
Date:3/1/2010

This release is available in Chinese.

It is known that fluctuations in the treatment outcome of photodynamic therapy (PDT) between patients are related to the concentration of photosensitizer in target tissue. The purpose of a study, by Wang et al, published in the February 2010 issue of Experimental Biology and Medicine was to establish a fluorescence method not only providing a semi-quantitative measurement of photosensitizer concentration but also predicting the efficacy of PDT for Port Wine Stains (PWS).

This work was conducted by Ying Wang and Xiaohua Liao when they were postgraduate students under the direction of Professor Ying Gu and Professor Rong Chen, and colleagues in the Department of Laser Medicine at the Chinese People's Liberation Army General Hospital. Currently, Ying Wang is a physician at Chinese PLA General Hospital, Xiaohua Liao works at Fujian Metrology Institute. An algorithm which can yield a semi-quantitative measurement of photosensitizer concentration was established in this study. Then a therapeutic effect correlation index (TECI) was proposed as the area under the photosensitizer concentration-time curve during PDT. The correlation between TECI and PDT treatment outcome was analyzed from 31 PWS patients at the Chinese People's Liberation Army General Hospital.

Dr. Wang noted that "A non-invasive fluorescence method that can monitor photosensitizer concentration during PDT for PWS was established, and a therapeutic effect correlation index (TECI) was verified to be positively correlated with PDT outcome for the first time in this paper."

Dr. Steven R. Goodman, Editor-in-Chief of Experimental Biology and Medicine said "The results of the study by Wang et al suggest that fluorescence spectroscopy can be used in situ to monitor skin photosensitizer concentration during PDT. This may provide a valuable diagnostic tool to predict PDT outcome."


'/>"/>

Contact: Dr. Ying Gu
guyinglaser@sina.com
Society for Experimental Biology and Medicine
Source:Eurekalert

Related biology news :

1. Novel technique for fluorescence tomography of tumors in living animals
2. Pitt researchers use fluorescence to develop method for detecting mercury in fish
3. Laser fluorescence could find life on Mars
4. Scripps scientists discover fluorescence in key marine creature
5. Volcano monitoring will target hazard threat to Marianas, US military and commercial jets
6. ACS webinar features developments in online water and wastewater monitoring
7. Listen to the natives for better moose monitoring
8. New Fujitsu UHF RFID Technology Implemented at Fairmont Pacific Rim Hotel for Advanced Inventory Monitoring
9. Breakthrough in monitoring tropical deforestation announced in Copenhagen
10. Ecologists sound out new solution for monitoring cryptic species
11. New beryllium reference material for occupational safety monitoring
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/11/2017)... DUBLIN , Apr. 11, 2017 Research ... Tracking Market 2017-2021" report to their offering. ... The global eye tracking market to grow at ... The report, Global Eye Tracking Market 2017-2021, has been prepared based ... report covers the market landscape and its growth prospects over the ...
(Date:4/5/2017)... -- Today HYPR Corp. , leading innovator in ... the HYPR platform is officially FIDO® Certified . ... that empowers biometric authentication across Fortune 500 enterprises and ... 15 million users across the financial services industry, however ... suites and physical access represent a growing portion of ...
(Date:3/30/2017)... The research team of The Hong Kong Polytechnic University (PolyU) ... ground breaking 3D fingerprint minutiae recovery and matching technology, pushing contactless ... use in identification, crime investigation, immigration control, security of access and ... ... A research team led by Dr Ajay Kumar ...
Breaking Biology News(10 mins):
(Date:6/22/2017)... ... June 22, 2017 , ... Tunnell Consulting’s ... and life sciences industries, continue to be in demand for their insights and ... be speaking on “The State of Information Governance in the Biopharmaceutical Industry” at ...
(Date:6/22/2017)... , ... June 22, 2017 , ... ... announced the release of Limfinity® version 6.5, a content-packed update to the Limfinity® ... to gain a larger and more diverse base of customers among labs and ...
(Date:6/20/2017)... ... June 20, 2017 , ... ... the CTNext board of directors has formed a Higher Education Entrepreneurship Advisory Committee ... composed of institution presidents and other high-ranking representatives from 35 higher education institutions ...
(Date:6/20/2017)... ... June 20, 2017 , ... HorizonScan is providing food and ... most likely threat to their products at the annual IFT conference in Las ... food expo attracts over 20,000 attendees representing food science professionals from over 90 ...
Breaking Biology Technology: