Navigation Links
Fluid equilibrium in prehistoric organisms sheds light on a turning point in evolution
Date:9/22/2011

Bethesda, Md. (Sept. 22, 2011) -- Maintaining fluid balance in the body is essential to survival, from the tiniest protozoa to the mightiest of mammals. By researching recent genomic data, Swiss researchers have found genetic evidence that links this intricate process to a turning point in evolution.

The study was led by Bernard Rossier, Professor Emeritus, University of Lausanne, along with colleagues Romain A. Studer, Emilie Person, and Marc Robinson-Rechavi. Dr. Rossier will discuss the team's findings at the 7th International Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels, sponsored by the American Physiological Society. Dr. Rossier's presentation, "Evolution of ENaC and Na-K-ATPase as Limiting Factors of Aldosterone Action," is based in part on the team's recent article published in the journal Physiological Genomics.

Timing Is Everything

In humans, the hormone aldosterone affects fluid balance by controlling the epithelial sodium channel (ENaC), a protein that traverses a cell's membrane and facilitates the movement of salt into and out of the cell. By searching for genes that descended from a common ancestral DNA sequence (homologs), the researchers found that the emergence of ENaC and Na, K-ATPase (sodium pump), an enzyme that also plays a role in sodium transport, coincided with the emergence of multi-celled organisms.

Dr. Rossier and his team focused their analysis on eukaryotesorganisms whose cells contain complex structures within enclosed membranesand sought to determine when and where on the eukaryotic family tree ENaC first appeared. When tracing the alpha, beta, and gamma subunits of ENaC back, the team found that the beta subunit appeared slightly before the emergence of Metazoans (multicellular animals with differentiated tissues) roughly 750 million years ago.

"The alpha subunit is an old protein found everywhere, in any kind of organism, but the beta and gamma subu
'/>"/>

Contact: Donna Krupa
dkrupa@the-aps.org
301-634-7209
American Physiological Society
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. Kalyon wins Thomas Baron Award in Fluid-Particle Systems
2. Animal and biological science highlights: San Antonio Fluid Dynamics Conference, Nov. 23-25
3. Uncultured bacteria found in amniotic fluids of women who experience preterm births
4. GEN reports on growing reliance on microfluidics technology
5. Study: Fluid buildup in lungs is part of the damage done by the flu
6. Amniotic fluid may provide new source of stem cells for future therapies
7. NIST-Cornell team builds worlds first nanofluidic device with complex 3-D surfaces
8. Microfluidic palette may paint clearer picture of biological processes
9. NIST calculations may improve temperature measures for microfluidics
10. Novel NIST connector uses magnets for leak-free microfluidic devices
11. Microfluidic integrated circuit could help enable home diagnostic tests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... scientists provide important new details on how climate change ... May 21 in the Journal of Animal Ecology ... accurate predictions and informing policymakers of how species are ... , "There is a growing recognition among biologists that ... another, and that this is going to have very ...
(Date:5/21/2013)... attached to a whale entangled in fishing gear, scientists ... a whale,s diving and swimming behavior. The monitoring revealed ... migrate, depletes their energy as they drag gear for ... death. , The scientists in this entanglement response suction-cupped ... female North Atlantic right whale called Eg 3911. The ...
(Date:5/21/2013)... Northwestern University researchers have developed a new method ... temporary holes in the cell surface. The technique ... and related biological fields. , Bulk electroporation ... through reversible nanopores in the cell membrane that ... is an increasingly popular method of cell ...
Breaking Biology News(10 mins):UCLA life scientists present new insights on climate change and species interactions 2UCLA life scientists present new insights on climate change and species interactions 3UCLA life scientists present new insights on climate change and species interactions 4UCLA life scientists present new insights on climate change and species interactions 5Study reveals how fishing gear can cause slow death of whales 2Study reveals how fishing gear can cause slow death of whales 3Single-cell transfection tool enables added control for biological studies 2
... 2010) Chesapeake Biological Laboratory Director Dr. Margaret Palmer ... for Environmental Science with its President,s Award for Excellence ... the public about the environmental impacts of mountaintop mining. ... to expand the impact of her research beyond academia ...
... - Imagine the marriage of hard metals or semiconductors to ... hybrid materials never conceived by Mother Nature. ... Steven Lenhert, the newest faculty face of nanoscience at The ... fitted with a "lab on a chip" that can diagnose ...
... jewel scarab beetles find each otherand hide from their ... for the blockbuster movie Avatar. According to researchers ... Chrysina gloriosa can distinguish between circularly polarized ... with a tremendous advantage, the researchers say, because most ...
Cached Biology News:UMCES ecologist Margaret Palmer recognized for promoting the role of science in public policy 2Bionanotechnology has new face, world-class future at Florida State 2Bionanotechnology has new face, world-class future at Florida State 3Beetles stand out using 'Avatar' tech 2
(Date:5/21/2013)... PALM BEACH, Fla. , May 21, 2013 ... (NYSE: FCN ), the global business ... enhance their enterprise value (the "Company"), announced that ... focused personnel that were formerly included within the ... and Litigation Consulting segment to form a single ...
(Date:5/21/2013)... The results of a new study led by ... computational evidence that nucleation of ice in small ... understanding water,s behavior at the nanoscale. The formation ... basic scientific research question whose answer also has ... , The crystallization of ice from supercooled ...
(Date:5/21/2013)... NC (PRWEB) May 21, 2013 ... financial services company for clinical trials, announced today ... Spend Solutions, LLC. Clinverse’s ClinPay® FLS eClinical ... investigator payment process. SpendMD ™, Aggregate ... complete solution for tracking and reporting transfer of ...
(Date:5/21/2013)... Miami, FL (PRWEB) May 21, 2013 ... and breakouts as contributor to acne. Recently physicians from ... effects of mental stress on the skin, and suggested ... to help reduce the chemicals produced from stress that ... aside from the negative feelings acne brings about, stress ...
Breaking Biology Technology:FTI Consulting Releases Realigned Segment Information Reflecting Newly Combined Health Solutions Practice 2Study led by GW professor provides better understanding of water's freezing behavior at nanoscale 2Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 2Clinverse, Inc. Announces Strategic Alliance with Aggregate Spend Solutions, LLC 3Adult Acne Treatment, Probiotic Action Explains How Hypnotherapy and Probiotics May Cure Various Skin Conditions 2
... T.J. Higley and Roy Eksteen, Tosoh Bioscience LLC, Montgomeryville, ... Introduction: , ... to ensure method , robustness. Factors ... are required to be consistent by GMP/GLP protocols. During a ...
... , Introduction ... that columns packed with smaller particles are , more ... packed with larger particles. The gain in efficiency is usually traded , ... shorter analysis , times and lower column back pressure. ...
... Amino Acids, RP-HPLC, Precolumn derivatisation, o-Phthalaldehyde (OPA), 2-Mercaptopropionic acid, ... Introduction: , ... light in the UV/visible spectrum. In order to increase sensitivity, ... the amino acids react with a precursor to yield ...
Cached Biology Technology:Mobile Phase Optimization for the Analysis of an Antibody-Based Fusion Protein and Aggregates using a TSKgel Super SW3000 Size-Exclusion Column 2Mobile Phase Optimization for the Analysis of an Antibody-Based Fusion Protein and Aggregates using a TSKgel Super SW3000 Size-Exclusion Column 3Three Micron TSK-GEL ODS-100V Columns for High Throughput LCMS 2ANALYSIS OF AMINO ACIDS BY REVERSED PHASE CHROMATOGRAPHY WITH PRECOLUMN DERIVATISATION AND UV/VISIBLE DETECTION 2ANALYSIS OF AMINO ACIDS BY REVERSED PHASE CHROMATOGRAPHY WITH PRECOLUMN DERIVATISATION AND UV/VISIBLE DETECTION 3
RABBIT ANTI HUMAN CHYMOTRYPSIN...
MSE ANTI CAN. CD3:FITC/RAT ANTI CD4:RPE...
MOUSE ANTI POLY (ADP-RIBOSE) Immunogen: Purified poly (ADP-ribose) polymer, 10-50 unit chain length...
... et.al. (1997) • Contains short ... biochemistry & molecular biology, arranged ... Entries give details of biochemical ... which they are involved and ...
Biology Products: