Navigation Links
Fluid equilibrium in prehistoric organisms sheds light on a turning point in evolution
Date:9/22/2011

Bethesda, Md. (Sept. 22, 2011) -- Maintaining fluid balance in the body is essential to survival, from the tiniest protozoa to the mightiest of mammals. By researching recent genomic data, Swiss researchers have found genetic evidence that links this intricate process to a turning point in evolution.

The study was led by Bernard Rossier, Professor Emeritus, University of Lausanne, along with colleagues Romain A. Studer, Emilie Person, and Marc Robinson-Rechavi. Dr. Rossier will discuss the team's findings at the 7th International Symposium on Aldosterone and the ENaC/Degenerin Family of Ion Channels, sponsored by the American Physiological Society. Dr. Rossier's presentation, "Evolution of ENaC and Na-K-ATPase as Limiting Factors of Aldosterone Action," is based in part on the team's recent article published in the journal Physiological Genomics.

Timing Is Everything

In humans, the hormone aldosterone affects fluid balance by controlling the epithelial sodium channel (ENaC), a protein that traverses a cell's membrane and facilitates the movement of salt into and out of the cell. By searching for genes that descended from a common ancestral DNA sequence (homologs), the researchers found that the emergence of ENaC and Na, K-ATPase (sodium pump), an enzyme that also plays a role in sodium transport, coincided with the emergence of multi-celled organisms.

Dr. Rossier and his team focused their analysis on eukaryotesorganisms whose cells contain complex structures within enclosed membranesand sought to determine when and where on the eukaryotic family tree ENaC first appeared. When tracing the alpha, beta, and gamma subunits of ENaC back, the team found that the beta subunit appeared slightly before the emergence of Metazoans (multicellular animals with differentiated tissues) roughly 750 million years ago.

"The alpha subunit is an old protein found everywhere, in any kind of organism, but the beta and gamma subu
'/>"/>

Contact: Donna Krupa
dkrupa@the-aps.org
301-634-7209
American Physiological Society
Source:Eurekalert

Page: 1 2

Related biology news :

1. Kalyon wins Thomas Baron Award in Fluid-Particle Systems
2. Animal and biological science highlights: San Antonio Fluid Dynamics Conference, Nov. 23-25
3. Uncultured bacteria found in amniotic fluids of women who experience preterm births
4. GEN reports on growing reliance on microfluidics technology
5. Study: Fluid buildup in lungs is part of the damage done by the flu
6. Amniotic fluid may provide new source of stem cells for future therapies
7. NIST-Cornell team builds worlds first nanofluidic device with complex 3-D surfaces
8. Microfluidic palette may paint clearer picture of biological processes
9. NIST calculations may improve temperature measures for microfluidics
10. Novel NIST connector uses magnets for leak-free microfluidic devices
11. Microfluidic integrated circuit could help enable home diagnostic tests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/4/2014)... BEACH GARDENS, Fla. , Dec. 3, 2014 ... management solutions, today announced that its DigitalPersona ® ... 4500 fingerprint readers have been deployed throughout First ... , South Carolina ... headquartered in Southern Pines, North Carolina ...
(Date:11/21/2014)... , November 18, 2014 According ... Market by Systems (Video, RFID, Access Control, Intrusion Detection, ... Hotels, Banks, Government), Component Service Geography - Global Forecasts ... Market is projected to be around $25 Billion in ... 2020, growing at a CAGR of 8.69%. ...
(Date:11/21/2014)... Wash. , Nov. 20, 2014 C-Labs ... for the Internet of Things (IoT), today announced the ... of chief operating officer. Previously a strategic advisor to ... finance, and operations. Mr. Traynor is based out of ... . He reports to Chris Muench , Chief ...
Breaking Biology News(10 mins):First Bank Partners with Crossmatch to Increase Log In Security 2First Bank Partners with Crossmatch to Increase Log In Security 3Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3C-Labs Names Former Microsoft and Bsquare Executive as Chief Operating Officer 2
... is a thermoplastic polyester which occurs naturally in bacteria ... . Even though PHB is biodegradable and is not ... too expensive to produce to replace petroleum-based plastics. New ... Microbial Cell Factories describes an alternative method of ...
... time, researchers have found a way to inject a precise ... living cell without a needle. The technique uses electricity ... and into a cell in a fraction of a second. ... University describe the technique in the online edition of the ...
... same time that a cell,s DNA gets duplicated, a third ... dense packing serves to repress or "silence" the DNA sequences ... the activity of nearby genes. When the cell divides, the ... cell,s DNA, but also the exact pattern in which that ...
Cached Biology News:Researchers do precise gene therapy without a needle 2Researchers do precise gene therapy without a needle 3Study reveals new role for RNA interference during chromosomal replication 2
(Date:12/19/2014)... -- Naurex Inc., a biopharmaceutical company leveraging its unique ... central nervous system, today announced that Norbert Riedel ... at the 33 rd annual J.P. Morgan Healthcare ... p.m. PST on Tuesday, January 13, 2015, at the ... About Naurex Inc. ...
(Date:12/19/2014)... Dec. 19, 2014 Research and Markets ... of the "Technology Innovations in Smart Fabrics ... http://photos.prnewswire.com/prnh/20130307/600769 ... Fabrics" offers a detailed assessment on technological advancements ... Findings: 1. The Smart Fabrics ...
(Date:12/19/2014)... 18, 2014 Ed Bilsky, Ph.D., vice ... Center for Excellence in the Neurosciences (CEN), and professor ... been selected as a member of the prestigious Dana ... neuroscientist from Maine to receive this honor. , ... entirely by the Dana Foundation. Its mission is ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 The ... to the rising ageing population and technological innovations ... and nutraceutical industries are catalysing the growth of ... @ http://www.marketsandmarkets.com/Market-Reports/empty-capsules-market-218018190.html , Scope of Report ... as well as new entrants/smaller firms to gauge ...
Breaking Biology Technology:Naurex to Present at 33rd Annual J.P. Morgan Healthcare Conference 2Technology Innovations in Smart Fabrics (Technical Insights) 2UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 2UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4
... Testing Market, FULLERTON, Calif., March 6 ... announced today that it has launched the ... integrated work cell which,consolidates chemistry and immunoassay ... to the company,s work cell family,combines Beckman ...
... Earlier Stage ... Chronic Kidney Disease Patients, CAMBRIDGE, Mass., March 6 ... launch of the phosphate binder,Renvela(R) (sevelamer carbonate) for dialysis patients, ... additional,approvals for the product., Genzyme has submitted a marketing ...
... SOUTH EASTON, Mass., March 6 Pressure,BioSciences, Inc. (Nasdaq: ... host,a teleconference to discuss its 2007 financial results and ... the teleconference either,by telephone or through a live web-cast. ... Wednesday March 12, 2008, Time: 4:30 p.m. Eastern ...
Cached Biology Technology:Beckman Coulter Releases the High-Volume UniCel(R) DxC 880i Integrated Work Cell 2Genzyme Launches Renvela(R) in the U.S. for Dialysis Patients 2Genzyme Launches Renvela(R) in the U.S. for Dialysis Patients 3Genzyme Launches Renvela(R) in the U.S. for Dialysis Patients 4Genzyme Launches Renvela(R) in the U.S. for Dialysis Patients 5Pressure BioSciences, Inc. to Discuss 2007 Financial Results and Provide Business Update 2
... mL pipets ,Angled acrylic pipet rack offers easy ... round pipet cans. Constructed of 6 mm (1/4 in.) ... x 76 mm H x 289 mm D (3 ... mm W x 406 mm H x 292 mm ...
...
CoverWell imaging chamber gasket with adhesive, one chamber, 20 mm diameter, 1.0 mm deep *set of 40* Cell Biology Imaging Tools and Accessories Microscope Slide Accessories...
...
Biology Products: