Navigation Links
Flu immunity is affected by how many viruses actually cause the infection
Date:6/28/2012

Bethesda, MDNot only does the type of flu virus affect a patient's outcome, but a new research report appearing in the Journal of Leukocyte Biology suggests that the number of viruses involved in the initial infection may be important too. Scientists from Canada found that when mice were infected by relatively high concentrations of the flu virus, they not only developed immunity against the virus that infected them, but this also promoted the generation of a type of immune cell in the lungs poised to rapidly react against infections with other strains of the flu, as well. Mice that were infected with a relatively low concentration of the virus developed weaker immunity against the strain that infected them, did not build up this crucial population of immune cells in the lungs, and showed only delayed immunity toward other flu strains. This discovery could pave the way for new prophylactic strategies to fight flu infections and provides a novel basis for vaccine design.

"Hopefully, the findings of our study will help to develop better vaccine preparations that will be more effective in inducing protective cellular immunity to fight against infectious pathogens such as bacteria, viruses and fungi," said Martin V. Richter, Ph.D., the lead researcher involved in the work from the Department of Medicine at the Universit de Sherbrooke and Centre de Recherche Clinique tienne-Le Bel in Qubec, Canada.

To make this discovery, scientists infected two groups of mice with two different infectious doses of influenza A (H3N2) and analyzed several aspects of inflammation and immunity during the initial infection as well as during reinfection with a different strain of virus. The first group was infected with a low dose of the virus whereas the second group was infected with a high dose of the same virus. Mice infected with the high dose showed increased morbidity, a greater degree of lung inflam
'/>"/>

Contact: Cody Mooneyhan
cmooneyhan@faseb.org
301-634-7104
Federation of American Societies for Experimental Biology
Source:Eurekalert

Page: 1 2

Related biology news :

1. Gut microbes battle a common set of viruses shared by global populations
2. Brothers in arms: Commensal bacteria help fight viruses
3. IU role in Human Microbiome Project exposes battle history between bacteria, viruses in human body
4. To spread, nervous system viruses sabotage cell, hijack transportation
5. Berkeley Lab scientists generate electricity from viruses
6. BGI, GMU, Mass. Eye and Ear and OUHSC announce agreement to sequence 100 human adenoviruses
7. Gene mutations cause massive brain asymmetry
8. Double the pain: RUB biologists find the cause of pain in the treatment of fair skin cancer
9. Glycogen accumulation in neurons causes brain damage and shortens the lives of flies and mice
10. Yeast cell reaction to Zoloft suggests alternative cause, drug target for depression
11. Changes in brains blood flow could cause brain freeze
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... invisible is probably the ultimate form of camouflage: you ... And this strategy is not as uncommon as you ... Baltimore County, USA, explains that the larval life stages ... one part of the anatomy that most creatures cannot ... eyes have to shield each individual eye unit with ...
(Date:9/17/2014)... UCLA atmospheric scientists were instrumental in the creation of ... tool to classify the fire threat potential of the ... a spark into an inferno. The index was introduced ... with UCLA and San Diego Gas and Electric. , ... to "extreme" that will be used to help fire ...
(Date:9/17/2014)... genetic disorder known as Jacobsen syndrome has been linked ... researchers at San Diego State University and the University ... treatment options for people with Jacobsen syndrome, the finding ... autism., Jacobsen syndrome affects approximately 1 in 100,000 people, ... in a person when there is a deletion at ...
Breaking Biology News(10 mins):Transparent larvae hide opaque eyes behind reflections 2UCLA scientists play key role in developing new Santa Ana Wildfire Threat Index 2A link between Jacobsen syndrome and autism 2
... is difficult to measure accurately each nation,s contribution of carbon ... the ground as coal, gas, and oil, and these fuels ... to generate the energy that is used to make products. ... countries where they are consumed. A team led by Carnegie,s ...
... The University of Texas at Austin whose technology developments in ... tens of thousands of patients with diseases such as cancer ... Institute of Medicine (IOM). Established in 1970, IOM is ... institute is considered one of the highest honors in health ...
... of spinal cord injury is receiving attention in the ... the department of biomedical engineering at NJIT, recently has ... micro-electrical stimulators for individuals with spinal cord injuries. ... year of support from a four-year, $1.4 million National ...
Cached Biology News:Links in the chain: Global carbon emissions and consumption 2UT professor elected to the Institute of Medicine of the National Academies 2UT professor elected to the Institute of Medicine of the National Academies 3NJIT researcher testing micro-electronic stimulators for spinal cord injuries 2
(Date:9/18/2014)... MX (PRWEB) September 18, 2014 September ... Mexico City, MX. ASEA is the manufacturer of the ... the skin care product, RENU28. , The Mexico ... Vice President Duvan Botero, and ASEA Field Leader Shawn ... holds a PhD in Atomic/Medical Physics from the University ...
(Date:9/17/2014)... INCLINE VILLAGE, Nev. , Sept. 17, 2014  PDL ... notified by its independent registered accounting firm, Ernst & Young ... The resignation was confirmed in a letter delivered to the ... 8-K filed on September 16, 2014.  PDL ... "We have received a number of inquiries on ...
(Date:9/17/2014)... -- The global consumption of squalene / squalane is expected ... skin-identical chemical that finds applications in various end user industries ... in other applications like high grade lubrication, and fiber coating ... players and is regionally segregated. Sophim ( France ... ( Japan ), SeaDragon Marine Oils Ltd. ( ...
(Date:9/17/2014)... , Sept. 17, 2014  The In Silico ... that will be featured at the conference, which takes ... on December 3 and 4, 2014. Researchers, students, drug ... to hear the following: KEYNOTE SPEAKERS ... Diego Skaggs School of Pharmacy Drug ...
Breaking Biology Technology:Announcing the ASEA Mexico Grand Opening Tour Beginning September 18th 2PDL BioPharma Issues Statement on Resignation of Ernst and Young as Corporate Auditors 2PDL BioPharma Issues Statement on Resignation of Ernst and Young as Corporate Auditors 3Squalene Market by Source (Animal & Vegetable) & by End-user Industry (Cosmetics, Pharmaceuticals & Food Industry) - Global Trends & Forecasts to 2019 2Squalene Market by Source (Animal & Vegetable) & by End-user Industry (Cosmetics, Pharmaceuticals & Food Industry) - Global Trends & Forecasts to 2019 3In Silico Drug Discovery Conference Announces Speakers and Topics 2In Silico Drug Discovery Conference Announces Speakers and Topics 3In Silico Drug Discovery Conference Announces Speakers and Topics 4In Silico Drug Discovery Conference Announces Speakers and Topics 5In Silico Drug Discovery Conference Announces Speakers and Topics 6In Silico Drug Discovery Conference Announces Speakers and Topics 7
... Amgen (Nasdaq: AMGN ) today announced that ... financial results on Monday, Jan. 24, 2011 after the close ... a conference call with the investment community at 2:00 p.m. ... Kevin Sharer, chairman and chief executive officer, and other members ...
... 2011 Sensus Healthcare is pleased to ... professional skin care products to be exclusively offered by ... Cases of skin cancer are on the rise and ... taking new aim at skin cancer (SM) in ...
... 2011 Cephalon, Inc., (Nasdaq: CEPH ) will hold ... founder and late Chairman and CEO on February 1, 2011, at ... Street, Philadelphia, Pennsylvania. Dr. Baldino founded Cephalon in ... one of the top ten biotechnology companies in the world. He ...
Cached Biology Technology:Amgen Announces Webcast of 2010 Fourth Quarter and Full Year Financial Results 2Sensus Healthcare Announces New Professional Skin Care Line - Sensus Skin Solutions™ 2Cephalon to Hold Public Memorial Service to Celebrate the Life of Company Founder, Frank Baldino, Jr., Ph.D. 2
Rat CINC-2 alpha/beta Affinity Purified Polyclonal Ab...
Tachykinin (H-2)...
...
... to significantly increase the shelf life of ... increased at room temperature storage conditions in ... is subjected to 0.45 micron filtration, and ... formulation insures consistently high levels of activity ...
Biology Products: