Navigation Links
Flu breakthrough: New drug developed to combat flu pandemic
Date:2/22/2013

The new drug has been proven to be effective in preventing the spread of different strains of influenza in laboratory models including resistant strains of the virus.

The breakthrough is the result of a global collaboration between scientists from CSIRO, the University of British Columbia and the University of Bath.

In order to infect cells, flu viruses bind onto sugars on the cell surface. To be able to spread they need to remove these sugars. The new drug works by preventing the virus from removing sugars and blocking the virus from infecting more cells. It is hoped the drug will also be effective against future strains of the virus.

According to the World Health Organisation, influenza kills approximately 500,000 people each year, with up to 2500 of those deaths occurring in Australia[1]. Costs to the Australian health care system are estimated to be more than A$85M, with more than 1.5 million work days lost annually

CSIRO scientist Dr Jenny McKimm-Breschkin, a researcher in the team that developed the first flu drug Relenza, said that understanding exactly how flu viruses become resistant to drugs has helped them to design a better flu drug.

"CSIRO researchers have shown that flu viruses continually mutate and some have become resistant to available treatments," Dr Jenny McKimm-Breschkin said.

"The new drug is effective against these resistant strains. As the site where the drug binds is found in all flu strains, the new drug is expected to be effective even against future flu strains.

"With millions of poultry currently infected with 'bird flu' globally, there are still concerns about its adaptation and potential to spread among humans, causing the next pandemic," she added.

Professor Steve Withers, University of British Columbia, has led the research team for the past seven years and said that although further studies are required to determine efficacy against a broader range of flu strains, the findings are extremely positive.

"Despite recent improvements in vaccine production, when a new strain of flu emerges it can take several months before vaccines are available to the public," Professor Steve Withers said.

"This antiviral drug would play an important role as the first line of defence in modulating disease severity and in controlling a pandemic while vaccines are prepared," he added.


'/>"/>

Contact: Angela Beggs
angela.beggs@csiro.au
61-395-452-977
CSIRO Australia
Source:Eurekalert

Related biology news :

1. Breakthrough: How salt stops plant growth
2. Research breakthrough: High brain integration underlies winning performances
3. University-developed omega-3-rich ground beef available soon
4. How the protein transport machinery in the chloroplasts of higher plants developed
5. High Brightness Tetrapod Quantum Dots Developed
6. Test developed to detect early-stage diseases with naked eye
7. New cranial neural crest cell line developed
8. Humanized mice developed at OHSU enable malaria research breakthrough at Seattle BioMed
9. New long-term antimicrobial catheter developed
10. Electronic nose prototype developed
11. Composite nanofibers developed by Penn scientists next chapter in orthopaedic biomaterials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/16/2017)... 2017 CeBIT 2017 - Against identity fraud with DERMALOG solutions "Made ... ... Used combined in one project, multi-biometric solutions provide a crucial contribution against identity ... Used combined in one project, multi-biometric ... ...
(Date:3/9/2017)... MOUNTAIN VIEW, Calif. , March 9, ... Simple," and 23andMe , the leading personal genetics ... choices.  Zipongo can now provide customers with personalized nutrition ... goals and biometrics, but also genetic markers impacting how ... Zipongo,s personalized food decision support platform uses biometrics ...
(Date:3/6/2017)... SAN MATEO, Calif. , March 6, 2017 ... predictive marketing and sales technology, today announced Predictive ... (AI) solution for infusing actionable sales intelligence into ... customers to automatically enable their sales organizations with ... contextual messages that allow for intelligent engagement. Predictive ...
Breaking Biology News(10 mins):
(Date:3/23/2017)... ... March 23, 2017 , ... Lajollacooks4u is proud to announce it has become the premiere ... cooking challenges for companies around the world, such as Illumina, HP and Qualcomm, and is ... for its increasing popularity is due to its new team building format, a way for ...
(Date:3/23/2017)... BETHESDA, Md. , March 23, 2017 /PRNewswire/ ... company developing DCVax® personalized immune therapies for solid ... on the $7.5 million financing it announced last ... Company sold to several institutional investors securities totaling ... $.26 per share, and 10,000,000 shares of Class ...
(Date:3/23/2017)... 23, 2017  GlobeImmune, Inc. today announced it has ... of 12,835,490 shares of its common stock to NantCell, ... connection with the sale of its common stock, NantCell ... issue to GlobeImmune 200,000 shares, an estimated $2.0 million ... "We are pleased to enter into this strategic agreement ...
(Date:3/23/2017)... , ... March 23, 2017 , ... ... recently selected by the Connecticut Technology Council (CTC) as a 2017 Women of ... thirteenth annual Women of Innovation Awards Dinner. , The dinner recognizes women accomplished ...
Breaking Biology Technology: