Navigation Links
Fish oil linked to increased risk of colon cancer in mice
Date:10/5/2010

EAST LANSING, Mich. Fish oil long encouraged by doctors as a supplement to support heart and joint health, among other benefits induced severe colitis and colon cancer in mice in research led by Michigan State University and published this month in the journal Cancer Research.

Jenifer Fenton, a food science and human nutrition researcher at MSU, led the research that supports establishing a dose limit for docosahexaenoic acid (DHA), one of the omega-3 fatty acids present in fish oil, particularly in people suffering from chronic conditions such as inflammatory bowel diseases.

"We found that mice developed deadly, late-stage colon cancer when given high doses of fish oil," she said. "More importantly, with the increased inflammation, it only took four weeks for the tumors to develop."

Specifically, the research team found an increase in the severity of the cancer and an aggressive progression of the cancer in not only the mice receiving the highest doses of DHA but those receiving lower doses as well. The mice used in the study were prone to inflammatory-like bowel disease; inflammation is an important risk factor for many types of cancers, including colon cancer.

"Our findings support a growing body of literature implicating harmful effects of high doses of fish oil consumption in relation to certain diseases," Fenton said. "Currently, there is a call by academics and the food industry to establish dietary guidelines for omega-3 consumption. This is primarily motivated by the fact that most Americans are deficient in omega-3 fatty acids, and there is substantial evidence supporting the beneficial effects of the consumption."

The findings were surprising, specifically because DHA has been shown to have some anti-inflammatory properties, according to Fenton: "We hypothesized that feeding fish oil enriched with DHA to mice would decrease the cancer risk; we actually found the opposite. These mice were less eq
'/>"/>

Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Gene variations that alter key enzyme linked to prostate cancer
2. Father absence linked to earlier puberty among certain girls
3. High testosterone levels linked to self-destructive CEO behavior, says Management Science
4. Low grades in adolescence linked to dopamine genes
5. High-fat diet during puberty linked to breast cancer risk later in life
6. Girls early puberty linked to unstable environment via insecure attachment in infancy
7. Fertilizer chemicals linked to animal developmental woes
8. USDA-backed study finds federal school lunches linked to childhood obesity
9. UCLA study identifies genetic variation linked to lupus in Asian men
10. Prenatal exposure to pesticides linked to attention problems
11. Gallbladder cancer may be linked to estrogens, says UH team
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... In the first broad-scale estimate of air pollution removal ... calculated that trees are saving more than 850 human ... respiratory symptoms. , While trees, pollution removal equated to ... percent, the impacts of that improvement are substantial. Researchers ... pollution at nearly $7 billion every year in a ...
(Date:7/25/2014)... the colonial era, 100,000s of people lived on the ... manipulated fire to control the availability of plants they ... continue to use fire to maintain desired habitat and ... U.S. Forest Service,s Pacific Southwest Station, will lead a ... Wildfire Refuge during the Ecological Society of America,s 99th ...
(Date:7/25/2014)... Terra satellite show the different areas that have been affected ... The burn scars show up as reddish-brown splotches of color ... the remote parts of Eastern Russia in the Sakha Republic. ... instrument, it is still possible to see the smoke rising ... below show the devastating number of fires that have plagued ...
Breaking Biology News(10 mins):First national study finds trees saving lives, reducing respiratory problems 2Fire ecology manipulation by California native cultures 2Fire ecology manipulation by California native cultures 3
... ON, July 19, 2013 Kidney patients who take calcium ... 22 per cent higher risk of death than those who ... by Women,s College Hospital,s Dr. Sophie Jamal. The study, ... the long-time practice of prescribing calcium to lower phosphate levels ...
... This news release is available in German . ... of text, the brain sends commands to arms and fingers to tap ... transfer this information as electrical pulses that trigger muscles to move. The ... along the spinal cord. For a long time, scientists assumed that ...
... media has expanded to reach an unlikely new target: ... Technology (NIST) have created networks of molecular data similar ... search would allow Facebook users to find all their ... NIST-designed networks could help scientists rapidly sift through enormous ...
Cached Biology News:Calcium linked to increased risk of heart disease and death in patients with kidney disease 2Haste and waste on neuronal pathways 2Haste and waste on neuronal pathways 3Haste and waste on neuronal pathways 4Facebook for molecules 2Facebook for molecules 3
(Date:7/26/2014)... Canada Endoscopy Visualization Systems Market Outlook ... Canada Endoscopy Visualization Systems market. The report provides ... units) and average prices (in US dollars) within ... Endoscopy Visualization Systems and Low-End Endoscopy Visualization Systems. ... , The report also provides company shares and ...
(Date:7/25/2014)... July 26, 2014 "Ischemic Stroke ... 2014" provides data on the Ischemic Stroke and ... elemental information and data relating to the clinical ... View full global Ischemic Stroke Research Report 2014 ... overview of the trial numbers and their recruitment ...
(Date:7/25/2014)... 2014 Amgen (NASDAQ: AMGN ) ... $0.61 per share dividend for the third quarter of ... 2014, to all stockholders of record as of the ... About Amgen Amgen is committed to unlocking the ... by discovering, developing, manufacturing and delivering innovative human therapeutics. ...
(Date:7/25/2014)... live in each person,s digestive tract. Scientists believe that ... off harmful infections, but their role in human health ... on the role of these bacteria, a team of ... tracked fluctuations in the bacterial populations of two research ... the July 25 issue of the journal Genome ...
Breaking Biology Technology:Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 2Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 3Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 4Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 5Ischemic Stroke and Cerebral Stroke Global Clinical Trials Review H2, 2014: MarketResearchReports.Biz 2Ischemic Stroke and Cerebral Stroke Global Clinical Trials Review H2, 2014: MarketResearchReports.Biz 3Amgen Announces 2014 Third Quarter Dividend 2Amgen Announces 2014 Third Quarter Dividend 3Monitoring the rise and fall of the microbiome 2Monitoring the rise and fall of the microbiome 3
... Materials Research Laboratory at UC Santa Barbara: an NSF ... from the National Science Foundation (NSF) to carry out ... years. Renewed NSF support ensures the vitality of materials ... energy, environment, and sustainability. Despite the challenging budgetary ...
... Sept. 12, 2011 McKesson Corporation ... McKesson Specialty Health , focused on empowering the ... technology and quality of care. (Logo:   ... support and business solutions, McKesson Specialty Health offers the ...
... Sept. 9, 2011 Palatin Technologies, Inc. (NYSE Amex: ... the Rodman & Renshaw Annual Global Investment Conference on Tuesday, ... will be held at The Waldorf Astoria in New York, ... Executive Officer of Palatin Technologies, will provide an update on ...
Cached Biology Technology:Major grant from the National Science Foundation will sustain UCSB materials research through 2017 2Major grant from the National Science Foundation will sustain UCSB materials research through 2017 3McKesson Corporation Unveils New Offerings to Empower the Community Patient Care Delivery System 2McKesson Corporation Unveils New Offerings to Empower the Community Patient Care Delivery System 3
capacity 250 mL...
... This CLS number is ... created to easily match ... showing no availability yet, ... old Sigma-Aldrich number (Z35,347-7) ...
Certified by the Biological Stain Commission. For staining fresh peripheral blood smears and blood parasites....
... Aminopropylsilane is perhaps the ... chemistry for microarray experiments. ... for Microarrays provide a ... for printing PCR products ...
Biology Products: