Navigation Links
First whole-genome lung cancer study by TGen and Virginia G. Piper Cancer Center set for conference
Date:7/6/2011

be used along with other information to help decide the best course of future treatment.

A review of well-characterized cancer-related genes found that a mutation resided in the TP53 gene, a mutation in the tumor (one base change in the genetic code), and that the mutation was always present in both the DNA and RNA. Such a mutation can halt the creation of tumor suppressor genes and result in the generation of a tumor. Interestingly, the cancer specimen showed no loss of heterozygosity (LOH), in which one side of the DNA's chromosome becomes inactive because of a mutation.

"This observation highlights the complexity of cancer and how different genetic mechanisms can alter a gene. This novel finding would not have been readily determined without the combined DNA and RNA integration approach," said Dr. David Craig, Associate Director of TGen's Neurogenomics Division, and also a senior author of the presentation.

Dr. Weiss said these investigative techniques will be used more often to pinpoint the origins of disease.

"In the future, with improved infrastructure and decreased costs, we anticipate that using NGS techniques will become more commonplace," Dr. Weiss said. "NGS has the potential to identify unique tumor aberrations at an unprecedented depth."

The conference is sponsored by the International Association for the Study of Lung Cancer (IASLC), which hosts a meeting every two years.


'/>"/>

Contact: Steve Yozwiak
syozwiak@tgen.org
602-343-8704
The Translational Genomics Research Institute
Source:Eurekalert

0

GOOD

Page: 1 2

Related biology news :

1. The loudest animal is recorded for the first time
2. New study documents first cookiecutter shark attack on a live human
3. First joint ESC/EAS guidelines for the management of dyslipidaemias
4. Prodigal plankton species makes first known migration from Pacific to Atlantic via Pole
5. Elsevier and ADSA announce winners of first annual Journal of Dairy Science Most Cited Awards
6. First genetic mutation linked to heart failure in pregnant women
7. First diagnostic test for hereditary childrens disease
8. First wood-digesting enzyme found in bacteria could boost biofuel production
9. First-of-its-kind fluorescence map offers a new view of the worlds land plants
10. Biochemist David Deamer explores how life began in new book, First Life
11. Registration opens for first Middle East and Africa osteoporosis meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... of potential environmental and human health effects from ... year has led scientists to recommend stronger government ... lithium-ion (Li-ion) battery materials. That,s the conclusion of ... Environmental Science & Technology . , Oladele A. ... have become mainstays for powering everything from smart ...
(Date:5/22/2013)... Early screening for prostate cancer could become as easy ... thanks to UC Irvine research published today in the ... After more than a decade of work, UC Irvine ... usable markers for prostate cancer in urine, meaning that ... accuracy and at dramatically lower cost. The same technology ...
(Date:5/21/2013)... device attached to a whale entangled in fishing gear, ... changed a whale,s diving and swimming behavior. The monitoring ... and migrate, depletes their energy as they drag gear ... slow death. , The scientists in this entanglement response ... two-year-old female North Atlantic right whale called Eg 3911. ...
Breaking Biology News(10 mins):UCI chemists devise inexpensive, accurate way to detect prostate cancer 2UCI chemists devise inexpensive, accurate way to detect prostate cancer 3Study reveals how fishing gear can cause slow death of whales 2Study reveals how fishing gear can cause slow death of whales 3
... American Society for Biochemistry and Molecular Biology expressed its ... Aug. 23 ruling in the U.S. District Court for ... barring federal funding of embryonic stem-cell research. In ... in response to a lawsuit filed by two adult ...
... Scripps Research Institute scientists have identified two proteins with potential ... of health problems, including pain, deafness, and cardiac and kidney ... Express, the advanced, online edition of the journal Science, on ... Research scientists identify two proteins, which they named Piezo1 and ...
... New Orleans, LA In a first person paper ... Obesity, Dr. Melinda Sothern, Director of Health Promotion and ... New Orleans, provides three ways to de-program the 1950s ... United States and protect future generations from its health ...
Cached Biology News:American Society for Biochemistry and Molecular Biology reacts to stem-cell ruling 2Scientists identify molecules involved in touch and other mechanically activated systems 2Scientists identify molecules involved in touch and other mechanically activated systems 3Scientists identify molecules involved in touch and other mechanically activated systems 4LSUHSC pediatric weight expert provides obesity trinity answers 2
(Date:5/22/2013)... SEABROOK, N.H. , May 22, 2013 /PRNewswire/ ... of the Year 2013" by Business NH Magazine.  ... recognized Granite State organizations that distinguish themselves with ... are very proud to receive this honor," said ... Superior Controls.  "As with any recognition, this award ...
(Date:5/22/2013)... Toronto, Ontario (PRWEB) May 22, 2013 ... of advanced sound therapy for tinnitus treatment. AudioNotch ... Destination Hearing . With clinic locations in both ... trusted provider of audiology and hearing services. AudioNotch's ... Zabell locations. , Upon entering a Destination Hearing ...
(Date:5/22/2013)... (PRWEB) May 22, 2013 Envera announced ... Fermentation Manager. Mr. McErlean has an extensive background ... leadership positions throughout his career. , Mike ... very pleased to have Mike join our team”. “Mike’s ... large scale fermentation and downstream processing equipment”, ...
(Date:5/21/2013)... , May 22, 2013 First ... formulation of glycopyrronium bromide designed using Prosonix, particle engineering ... developing a portfolio of inhaled Respiratory Medicines by ... with PSX1002 that will assess its effect on lung ... in patients with moderate to severe chronic obstructive pulmonary ...
Breaking Biology Technology:Superior Controls of Seabrook, NH named Business of the Year for 2013 by Business NH Magazine 2AudioNotch Tinnitus Treatment Launches Partnership With Destination Hearing 2Envera Appoints Michael McErlean Fermentation Manager 2Prosonix Initiates Phase 2 Clinical Study with PSX1002 in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) 2Prosonix Initiates Phase 2 Clinical Study with PSX1002 in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) 3Prosonix Initiates Phase 2 Clinical Study with PSX1002 in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) 4
... the Anniversary by Ringing The Closing Bell(R) at ... the ... Edwards,Lifesciences Corporation (NYSE: EW ), a world leader in ... of partnering with clinicians to develop life-saving,innovations. To celebrate its five ...
... Anadys,Pharmaceuticals, Inc. (Nasdaq: ANDS ) announced today ... Conference on Wednesday, April 9, 2008,at 3:00 p.m. EDT ... the St.,Regis Hotel in New York City., Steve ... Inc., will present an overview of Anadys and an ...
... 2, 2008 BioSpace, the world,s,leading online bioscience job ... Bio NC(TM) Career Fair on Thursday, May 1, 2008. ... from 11 am to 4 pm., (Logo: ... North Carolina will attend the,biotech job fair to meet ...
Cached Biology Technology:Edwards Lifesciences Celebrates 50 Years of Life-Saving Innovations 2Edwards Lifesciences Celebrates 50 Years of Life-Saving Innovations 3Anadys Pharmaceuticals to Present at the CanAccord Adams Hepatitis C Conference 2Bioscience Career Fair in North Carolina Expected to Attract Well Qualified Job Seekers 2
... cocktail of 3 siRNAs specifically targeted to ... popular product. The siTrio reagent guarantees you ... target gene when used under standard conditions ... of optimal transfection with one of B-Bridges ...
... siTrio siRNA --- a cocktail of ... gene of interestis our most popular product. ... than 75% knockdown of your target gene ... siRNA for transfection and confirmation of optimal ...
... suitable for a wide range of molecular ... Pulsed Field Gel Electrophoresis (PFGE). Due to ... Multi ABgarose can effectively separate large DNA ... turn means reduced band diffusion, a problem ...
... molecular screening, low melting point agarose where ... is recommended for separation of nucleic acids ... PCR products. Micro ABgarose is also suited ... for blotting techniques. At a 3% concentration, ...
Biology Products: