Navigation Links
First use of high-field MRI in developing brain reveals previously undetectable injuries
Date:11/7/2011

PORTLAND, Ore. -- Pediatric neuroscientists at Oregon Health & Science University Doernbecher Children's Hospital are the first to use high magnetic field strength MRI to reveal tiny white matter injuries in the developing brain previously undetectable using standard MRI.

Early, accurate identification of these lesions in the preterm human infant could prevent delays in therapy and enable physicians to inform families sooner of the potential for complications. The team's findings are published in the Annals of Neurology.

White matter injury is the most common cause of chronic neurologic disability in children with cerebral palsy, explains principal investigator Stephen Back, M.D., Ph.D., but babies with cerebral palsy often have MRIs that miss injury, which creates significant challenges, including delayed treatment intervention and rehabilitation.

"Until now there hasn't been a compelling reason to put preterm babies into a high-field MRI scanner. Our work indicates the magnetic field strength of current clinical MRI may be a limiting factor to detecting some white matter lesions in the preterm infant. Now that we can detect this injury, we also hope our findings may encourage MRI researchers to find more sensitive means to detect this injury with lower field MRIs that are widely available," said Back, an associate professor of pediatrics and neurology in the Pap Family Pediatric Research Institute at OHSU Doernbecher Children's Hospital.

High-field MRI scanners are still mostly used as a research tool and not widely available outside of specialized MRI research centers like OHSU, Back added.

White matter injury occurs during brain development when nerve fibers are actively being wrapped in myelin, the insulation that allows nerve fibers to rapidly transmit signals in the brain. The cells required to make myelin can be easily destroyed when blood flow to the developing brain falls below normal or when matern
'/>"/>

Contact: Tamara Hargens-Bradley
hargenst@ohsu.edu
503-494-8231
Oregon Health & Science University
Source:Eurekalert

Page: 1 2

Related biology news :

1. New way to make malaria medicine also first step in finding new antibiotics
2. Complete Genomics launches, becomes worlds first large-scale human genome sequencing company
3. Digital zebrafish embryo provides the first complete developmental blueprint of a vertebrate
4. Synaptics to Report First Quarter Results on October 23
5. Alzheimers disease research attracts first partner
6. Volcanoes may have provided sparks and chemistry for first life
7. Study of polar dinosaur migration questions whether dinosaurs were truly the first great migrators
8. Synaptics Reports Record Results for First Quarter of Fiscal 2009
9. First comprehensive genomic study of common cold reveals new treatment targets
10. Scientists achieve first tracking of salmon from headwaters in Rockies through Pacific to Alaska
11. First results from hospital trials testing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... BostonThe American Society for Bone and Mineral Research awarded ... of Medicine (BUSM), with the 2014 Louis V. Avioli ... at BUSM, is internationally known for revolutionizing the understanding ... , The award honors a member of the ... fundamental contributions to bone and mineral basic research. It ...
(Date:7/11/2014)... of Standards and Technology (NIST) need a special ... often prove that necessity is truly the mother ... M. Lorna De Leoz and Stephen Stein, NIST ... Glycomics is the study of the abundant, often-branched ... proteins and lipids and influence cellular processes, including ...
(Date:7/11/2014)... of researchers, including scientists from the Max Planck Institute ... a major step in understanding photosynthesis, the process by ... oxygen in its atmosphere and which is therefore crucial ... , The researchers report the first direct visualization of ... step in which a specific protein complex, photosystem II, ...
Breaking Biology News(10 mins):BUSM's Michael F. Holick receives American Society for Bone and Mineral Research award 2A first direct glimpse of photosynthesis in action 2
... Chinese . College Park, MD (August 3, 2010) ... in molecular biology today. The devices, which can be used ... sequences, are employed in everything from forensic analysis to disease ... colleagues at Simon Fraser University in Burnaby, Canada have combined ...
... YORK, N.Y., August 3, 2010) Autism Speaks, ... importance of research on environmental risk factors for ... on Environment & Public Works, Subcommittee on Children,s ... health factors associated with autism spectrum disorders (ASD) ...
... of dollars to cap it, and it could take billions ... Gulf of Mexico is acknowledged the environmental catastrophe of the ... help "bioremediate" the remaining problems. Prof. Eugene Rosenberg ... Molecular Microbiology and Biotechnology are using naturally occurring oil-munching bacteria, ...
Cached Biology News:Autism Speaks on US Senate hearing on potential environmental health factors in autism 2Autism Speaks on US Senate hearing on potential environmental health factors in autism 3A nemesis for oil spills 2
(Date:7/10/2014)... 10, 2014  Franciscan St. Anthony Health-Crown ... for respiratory monitoring outside the operating room, ... in embracing state-of-the-art patient safety technology. ... breathing and can alert medical caregivers when ... amount of carbon dioxide the patient is ...
(Date:7/10/2014)... OAKS, Calif., July 10, 2014   Ceres, Inc ... and seed company, announced today financial results for the ... update on its business. Ceres reported that ... in product performance this growing season in Brazil, which ... affected the company,s sorghum evaluation areas for part of ...
(Date:7/10/2014)... extremely challenging because there are many genetic variants that ... Now investigators reporting in the July 3rd issue of ... describe a strategy that may help reveal how such ... environmental exposures to affect the development of the nervous ... predispose individuals to schizophrenia. , The work takes ...
(Date:7/10/2014)... the University of Illinois at Urbana-Champaign provides new ... of spin and heat at the nanoscale, and ... for data storage and information processing. , ... momentum. In a typical charge current, electrons, spin-angular-momentum ... explained David Cahill, a professor of materials science ...
Breaking Biology Technology:Franciscan St. Anthony Health-Crown Point Underscores Patient Safety Commitment Through Expanded Use of Capnography 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 3Ceres Announces Fiscal Third Quarter 2014 Financial Results 4Ceres Announces Fiscal Third Quarter 2014 Financial Results 5Ceres Announces Fiscal Third Quarter 2014 Financial Results 6Ceres Announces Fiscal Third Quarter 2014 Financial Results 7Ceres Announces Fiscal Third Quarter 2014 Financial Results 8Ceres Announces Fiscal Third Quarter 2014 Financial Results 9New strategy could uncover genes at the root of psychiatric illnesses 2University of Illinois study advances limits for ultrafast nano-devices 2
... would let you see a virus in a drop of blood ... says Durdu Guney, make ultra-high-resolution microscopes as commonplace as cameras in ... also known as a perfect lens, though people are trying. Optical ... limit, so even the best won,t usually let us see objects ...
... of electronics at the nanoscale may be even ... conductance in ferroelectric nanodomains by researchers at Oak ... their polarization with the application of an electric ... as ultrasound machines and sensors. Now, discoveries about ...
... 2012 Advanstar|CBI recently announced the full agenda for ... Forum takes place March 6-7, 2012 in Baltimore, MD. ... Eli Lilly, Genentech, AstraZeneca, Shire Human Genetic Therapies and ... Needy Meds recently interviewed PAP,s Senior Program Manager, Sharon ...
Cached Biology Technology:Almost perfect: A breakthrough in superlens development 2ORNL experiments prove nanoscale metallic conductivity in ferroelectrics 2
... using advanced automated high throughput microplate processing equipment that dispenses ... accommodate virtually any lot size of the following formats (with ... 8 and 12 well strips, ... 384 well microplate, 1536 ...
... are based on well-established periodate chemistry, ... and reproducible. This kit contains all ... or antibody, including ready-to-use buffers and ... HRP is supplied ready-to-use and requires ...
... Acridinium NHS ester can be ... nucleic acids. The covalently bound ... chemiluminescence in the presence of ... proteins can be used as ...
... hold up to 6 strain chambers with precise ... use design ensures that cells grow over long ... compression. This unit allows you to control the ... 64 unique strain settings. The instrument fits in ...
Biology Products: