Navigation Links
First use of high-field MRI in developing brain reveals previously undetectable injuries
Date:11/7/2011

PORTLAND, Ore. -- Pediatric neuroscientists at Oregon Health & Science University Doernbecher Children's Hospital are the first to use high magnetic field strength MRI to reveal tiny white matter injuries in the developing brain previously undetectable using standard MRI.

Early, accurate identification of these lesions in the preterm human infant could prevent delays in therapy and enable physicians to inform families sooner of the potential for complications. The team's findings are published in the Annals of Neurology.

White matter injury is the most common cause of chronic neurologic disability in children with cerebral palsy, explains principal investigator Stephen Back, M.D., Ph.D., but babies with cerebral palsy often have MRIs that miss injury, which creates significant challenges, including delayed treatment intervention and rehabilitation.

"Until now there hasn't been a compelling reason to put preterm babies into a high-field MRI scanner. Our work indicates the magnetic field strength of current clinical MRI may be a limiting factor to detecting some white matter lesions in the preterm infant. Now that we can detect this injury, we also hope our findings may encourage MRI researchers to find more sensitive means to detect this injury with lower field MRIs that are widely available," said Back, an associate professor of pediatrics and neurology in the Pap Family Pediatric Research Institute at OHSU Doernbecher Children's Hospital.

High-field MRI scanners are still mostly used as a research tool and not widely available outside of specialized MRI research centers like OHSU, Back added.

White matter injury occurs during brain development when nerve fibers are actively being wrapped in myelin, the insulation that allows nerve fibers to rapidly transmit signals in the brain. The cells required to make myelin can be easily destroyed when blood flow to the developing brain falls below normal or when matern
'/>"/>

Contact: Tamara Hargens-Bradley
hargenst@ohsu.edu
503-494-8231
Oregon Health & Science University
Source:Eurekalert

Page: 1 2

Related biology news :

1. New way to make malaria medicine also first step in finding new antibiotics
2. Complete Genomics launches, becomes worlds first large-scale human genome sequencing company
3. Digital zebrafish embryo provides the first complete developmental blueprint of a vertebrate
4. Synaptics to Report First Quarter Results on October 23
5. Alzheimers disease research attracts first partner
6. Volcanoes may have provided sparks and chemistry for first life
7. Study of polar dinosaur migration questions whether dinosaurs were truly the first great migrators
8. Synaptics Reports Record Results for First Quarter of Fiscal 2009
9. First comprehensive genomic study of common cold reveals new treatment targets
10. Scientists achieve first tracking of salmon from headwaters in Rockies through Pacific to Alaska
11. First results from hospital trials testing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Munich report that a new class of chemical ... drugs. They have also pinpointed the relevant target ... agents. , Researchers led by LMU,s Professor ... Technische Universitt Mnchen have identified a class of ... the fight against malignant tumors. The compound is ...
(Date:9/30/2014)... , Sept. 30, 2014  Spectra ... solutions for the biotech and power generation ... new RECONN Bioprocess Manager, an easy-to-use and ... geared towards bioprocess development laboratories. ... disparate bioreactor and analyzer systems. Accessing and ...
(Date:9/29/2014)... Clostridium ramosum , coupled with a high-fat diet, may cause ... in mBio , the online open-access journal of the ... the German Institute of Human Nutrition Potsdam-Rehbruecke in Nuthetal observed ... gained weight when fed a high-fat diet. Mice that ... even when consuming a high-fat diet, and mice that had ...
Breaking Biology News(10 mins):Cancer therapy: Driving cancer cells to suicide 2Spectra Automation Introduces RECONN Bioprocess Manager 2Gut bacteria promote obesity in mice 2
... Bethesda, MD FASEB MARC (Maximizing Access to ... recipients for the American Association of Immunologists 2013 ... from July 13-18, 2013. These awards are meant ... scientists from underrepresented groups into the mainstream of ...
... progress in the search for the first broad-spectrum drugs ... common infectious diseases. Their study on these potential drugs ... the journal ACS Medicinal Chemistry Letters . ... HRV infections cause mild disease, they can lead to ...
... teachers to sing melodies accurately, according to a new ... the University of Kaiserslautern in Germany. Their analysis of ... songbirds, brain processes. The work is published online in ... is considered to be one of the most complex ...
Cached Biology News:Songbirds turn on and tune up 2
(Date:9/30/2014)... , September 30, 2014 ... intuitive browsing of chemistry in documents ... software solutions and consulting services for life science ... information and generate Markush structures from documents. ... organizations intellectual property, however generating and understanding Markush ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 OriginOil Inc. ... high-speed, chemical-free process to clean up large quantities of ... CEO Riggs Eckelberry reported on the launch of the ... a site provided by partner STW Resources . ... 1000 barrels per day (bpd) and achieved a 99.8% ...
(Date:9/30/2014)... BALTIMORE and ROCKVILLE, Md., Sept. 30, 2014 /PRNewswire/ ... private-public partnership focusing on commercializing market-relevant biohealth innovations and ... Maryland , announced today that venture capitalist, ... as a strategic advisor. Dr. Fernandez will be a ... Gap Fund, which will provide up to $50 million ...
(Date:9/30/2014)... iLab Solutions announced the results of its ... on core facility operations, growth and utilization as well ... In its 4th year running, a number of long-term ... decrease in the percentage of revenue that comes from ... constraints of this trend. When asked, “What are your ...
Breaking Biology Technology:ChemAxon Introduces ChemCurator for Chemical Information Extraction and Markush Structure Creation 2OriginOil, Inc. Report to Shareholders: Blue Gold in West Texas 2Seasoned Life Sciences Venture Capitalist Tania Fernandez Joins BHI to Help Manage New BioHealth Gap Fund 2iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 2iLab Solutions Announces the Results of the 2014 Core Facility Benchmarking Study 3
... Kansas to its annual promotional campaign of biotechnological, pharmaceutical and medical device companies ... , , (Logo:   ... (Logo:   http://www.newscom.com/cgi-bin/prnh/20040907/CLTU006LOGO ) , ... The leading employment Web site for the life sciences launched the ...
... July 29 Omeros Corporation (Nasdaq: OMER ) ... facility under which it may sell up to $40 ... Opportunity, Ltd. (the "investor") over a 24-month period. Omeros is ... enter into and consummate other equity, debt and non-dilutive financing ...
... ,, LONDON , ... pleased,to announce the appointment of Dr Neill Moray Mackenzie ... to CMPT a long record of executive,board level management ... Genetics Ltd, Oxford Biomedica plc (an LSE,listed company), Avidex ...
Cached Biology Technology:BioSpace Showcases the Midwest's Growing Life Science Region 2BioSpace Showcases the Midwest's Growing Life Science Region 3Omeros Secures $40 Million Committed Equity Financing Facility 2Omeros Secures $40 Million Committed Equity Financing Facility 3Omeros Secures $40 Million Committed Equity Financing Facility 4CMP Therapeutics Appoints Dr Neill Moray Mackenzie as CEO 2CMP Therapeutics Appoints Dr Neill Moray Mackenzie as CEO 3CMP Therapeutics Appoints Dr Neill Moray Mackenzie as CEO 4CMP Therapeutics Appoints Dr Neill Moray Mackenzie as CEO 5
Human DCIR/CLEC4A Phycoerythrin MAb (Clone 216110)...
Recombinant Mouse Wnt-3a...
One-step, microplate or cuvet, colorimetric, linear detection range 8 mg/dL to 300 mg/dL. Procedure: 5 min....
dynactin 4, mRNA (cDNA clone MGC:3248 IMAGE:3505855), complete cds...
Biology Products: