Navigation Links
First study to reveal how paracetamol works could lead to less harmful pain relief medicines
Date:11/22/2011

tion for a painkiller.'

The researchers say that if they can identify other analgesic compounds similar to paracetamol that use the same TRPA1 pathway to prevent pain signals sent by nerve cells to the brain, it is possible that they can find a compound that does not have toxic effects and will reduce the risk of overdose.

Dr Andersson concludes: 'This study validates TRPA1 as a new target for pain relief drugs. Many targets have been identified in the past, but as paracetamol is a medicine that we know works well in humans, this gives us a head-start in looking for effective molecules that utilise the same pathways but are less harmful.'


'/>"/>
Contact: Katherine Barnes
katherine.barnes@kcl.ac.uk
44-020-784-83076
King's College London
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. West coast log, lumber exports in first 9 months of 2011 surpass 2010 totals
2. Paleontologist describes large nest of juvenile dinosaurs, first of their genus ever found
3. Worlds first stem cell bandage in human clinical trials
4. NASAS NPP satellite acquires first ATMS measurements
5. Berkeley Lab researchers create first of its kind gene map of sulfate-reducing bacterium
6. First UN carbon offset project certified
7. First use of high-field MRI in developing brain reveals previously undetectable injuries
8. Poor sleep quality in first, third trimesters linked to preterm births
9. Research team clarifies mechanics of first new cell cycle to be described in more than 20 years
10. Scientists measure dream content for the first time
11. A*STAR scientists first to identify stem cell key to lung regeneration
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2014)... twist to the story of how barnyard chickens came to ... the journal Proceedings of the National Academy of Sciences ... lived 200-2300 years ago in Europe, researchers report that just ... far different from the chickens we know today. , The ... modern domestic chickens -- such as their yellowish skin -- ...
(Date:4/17/2014)... trials to treat tuberculosis could be the basis for ... bacteria, fungal infections and parasites, yet evade resistance, according ... collaborators. , Led by U. of I. chemistry professor ... drug SQ109 attacks the tuberculosis bacterium, how the drug ... to malaria and how targeting multiple pathways reduces ...
(Date:4/17/2014)... study suggests that fish consumption advisories for expecting ... long-lived contaminants like persistent organic pollutants (POPs). ... researchers including University of Toronto Scarborough PhD student ... how different levels of environmental contamination, a mother,s ... in the body influenced exposure in her children. ...
Breaking Biology News(10 mins):Ancient DNA offers clues to how barnyard chickens came to be 2Multitarget TB drug could treat other diseases, evade resistance 2Fish consumption advisories fail to cover all types of contaminants 2
... about the impact on global climate of water evaporated ... concludes that evaporated water helps cool the earth as ... demonstrating that evaporation of water from trees and lakes ... These findings, published September 14 in Environmental Research ...
... at the University of California, Riverside,s Center for Environmental ... Engineering have received two grants to further explore a ... fuels. "These grants allow for the continued happy ... research engineer at CERT. "This research has the potential ...
... For those fascinated by microbes, infection, or how medical ... Infectious Diseases, a new book just published by ASM Press, ... whose work changed the way we think about and treat ... Gaynes describes the genesis of the germ theory of disease ...
Cached Biology News:Water evaporated from trees cools global climate 2Turning waste into inexpensive, green fuel 2Turning waste into inexpensive, green fuel 3The remarkable history of medicine's battle with infectious diseases 2
(Date:1/15/2014)... SAN JOSE, California , January 15, 2014 ... conjugates for cancer, today announced the appointment of Thomas C ... has over 20 years, development experience gained in the biotechnology ... "I am delighted to welcome Tom at this ...
(Date:1/15/2014)... January 15, 2014 More than 5 ... about 1 in 3 seniors will die with Alzheimer’s ... These jaw-dropping figures have shocked many Americans into looking ... help prevent these tragic age-related cognitive disorders. Jonathan Weisman, ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 2013 was ... Scottsdale’s Brain State Technologies®. They saw continued independent research ... Center who were awarded a $1 million grant from ... in “Brain and Behavior” a peer reviewed journal, Amy ...
(Date:1/14/2014)... 14, 2014 Date: Friday, April 11, 2014 ... Country Club, 1360 Almshouse Road, Warrington, Pa. , ... solely dedicated to finding a cure for hepatitis B and ... host its annual Crystal Ball on Friday, April 11 at ...
Breaking Biology Technology:Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 2Oxford BioTherapeutics Appoints Thomas C Reynolds MD, PhD to its Board of Directors 3Biohack Pure Offers 5 Tips for Increasing Memory in 2014 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3Hepatitis B Foundation to Host Annual Crystal Ball Gala 2
... Monsanto Company,s (NYSE:,MON) Brett Begemann, executive ... Casale, executive vice president of strategy and,operations, ... two,conferences later this month., Both Monsanto ... company,s,business performance and expectations, strategic initiatives, product,performance, ...
... on Company,s web site, GERMANTOWN, Md., Feb. ... a pharmaceutical company focused on,developing and commercializing novel ... MiddleBrook president and CEO, will,deliver a corporate presentation ... Time., The presentation will take place as ...
... N.J., Feb. 5 Covance Inc. (NYSE:,CVD) today announced ... Biotechnology and Medical Device Conference on February 6th,at 9:20 ... the presentation at, http://www.covance.com . In order to register ... early., Covance, with headquarters in Princeton, New Jersey, ...
Cached Biology Technology:MiddleBrook Pharmaceuticals to Present at BIO CEO & Investor Conference 2008 2