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First partial sequencing of an Iberian pig
Date:3/22/2011

Researchers of the Faculty of Veterinary Medicine at Universitat Autnoma de Barcelona (UAB) and of the Centre for Research in Agricultural Genomics (CRAG), the Centre for Genomic Regulation (CRG) in Barcelona, the National Institute for Agrarian Technology and Research in Madrid and Wageningen Research Center (WUR, the Netherlands) have published the first partial genome sequencing of an Iberian pig. Using next-generation sequencing techniques, researchers have been able to sequence and analyse 1% of the genome. This is the first time an individual pig genome-sequence is published. The project, coordinated by ICREA researcher Miguel Prez-Enciso, has been published in the online edition of the journal Heredity.

The sequenced animal is an Iberian sow from the Guadyerbas strain, a highly particular line which has been kept isolated on an experimental farm belonging to the government of Castilla-La Mancha and located in Oropesa, near Toledo, since 1945, thanks to years of work by INIA researchers. The Guadyerbas line thus represents one of the first original strains of the Iberian pig in Spain. These animals have a good appetite, are slow-growing, obese, hairless and black coloured. UAB and INIA teams have used these animals in several experiments aimed at identifying the genetic basis of the highly reputed meat quality of Iberian pigs. Researchers expect therefore that a complete sequencing could offer clues on these and other characteristics.

The sequenced animal is highly inbred, since the herd has been isolated for over 50 years. Researchers have taken this into account with the intention of using a particularly 'homogeneous' species presenting little variability. Nevertheless, data from the sequencing offer surprising results, such as a higher than expected level of variability. Despite being highly inbred, a diversity which represents approximately half of all European populations can be observed. This aspect is importa
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Contact: Maria Jesus Delgado
MariaJesus.Delgado@uab.cat
34-935-814-049
Universitat Autonoma de Barcelona
Source:Eurekalert

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