Navigation Links
First individual genome sequence published
Date:9/3/2007

vered 7.5 times, ensuring that each set of contributing chromosomes was covered over 3.2 times for greater than 96% coverage of the two parental genomes. The team at JCVI compared and contrasted the new HuRef diploid genome sequence to earlier versions of published human genomes and found that the HuRef version improved upon both these early versions by providing more and correctly oriented base pairs.

Since the HuRef genome is diploid, each of the parental chromosomes could be directly compared to each other. One of the most surprising and important findings from this research was the high degree of genetic variation that was found between two chromosomes within a single individual.

Each time we peer into the human genome, we uncover more valuable insight into our intricate biology, said Dr. Venter. With this publication, we have shown that human-to-human variation is more than seven-fold greater than earlier estimates, proving that we are in fact very unique individuals at the genetic level. He added, It is clear, however, that we are still at the earliest stages of discovery about ourselves, and only with continued sequencing of more individual genomes will we be able to garner a full understanding of how our genes influence our lives.

Within the human genome, there are different kinds of DNA variants. The most studied type is single nucleotide polymorphisms, or SNPs. These have long been thought to be the most prevalent and perhaps the most important type of variant implicated in human traits and disease susceptibility. However, in this analysis of Dr. Venters genome, the team found a surprising number of other important variants. A total of 4.1 million variants covering 12.3 million base pairs of DNA were uncovered with more than 1.2 million new variants discovered.

Of the 4.1 million variations between chromosome sets, 3.2 million were SNPs, while nearly one million were other kinds of variants, such as insertion/deletio
'/>"/>

Contact: Natalie Bouaravong
press@plos.org
415-568-3445
Public Library of Science
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. A genes first kiss sets off that affair known as puberty
2. Timing is everything: First step in protein building revealed
3. Emory Eye Center Implants Its First Retinal Chips In Patients With Retinitis Pigmentosa
4. First atlas of key brain genes could speed research on cancer, neurological diseases
5. First-ever Compounds To Target Only Metastatic Cells Are Highly Effective Against Breast, Prostate, And Colon Cancers
6. NYCs First Rapid HIV Drug-resistant AIDS Case Prompts Call to Step Up HIV Prevention
7. First real-time view of developing neurons reveals surprises, say Stanford researchers
8. Love at first smell
9. Worlds largest rainforest drying experiment completes first phase
10. PCRM develops worlds first cruelty-free insulin assay
11. Breast-Cancer Risk Linked to Exposure to Traffic Emissions at Menarche, First Birth
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... RUSTON, La. A team of researchers ... innovative method for using affordable, consumer-grade 3D ... implants that can contain antibacterial and chemotherapeutic ... team comprised of doctoral students and research ... nanosystems engineering programs collaborated to create filament ...
(Date:8/21/2014)... Carolina State University have developed a novel and versatile ... applications for creating new materials as well as for ... technique allows us to model much larger and more ... quickly," says Nan Li, lead author of a paper ... State,s Department of Materials Science and Engineering. "This is ...
(Date:8/20/2014)... a John and Rebecca Moores Professor of Biology and Biochemistry ... in the International Society for the Study of the Origin ... members two from the U.S., one from France and ... are elected every three years, and 36 have been named ... 20 countries, the ISSOL includes researchers from disciplines as varied ...
Breaking Biology News(10 mins):Louisiana Tech University researchers use 3D printers to create custom medical implants 2Louisiana Tech University researchers use 3D printers to create custom medical implants 3Researchers develop models to study polyelectrolytes, including DNA and RNA 2UH professor named fellow by International Astrobiology Society 2
... mouth bacteria behaving badly and the hundreds of microbial ... of the highlights at the Society for General Microbiology,s ... event takes place on 6-9 September at the Jubilee ... will present cutting-edge scientific research covering a wide range ...
... Ohio Normally, the brilliant red of a male cardinal ... that may not be true of cardinals living in urban ... bright red feather coloration of male northern cardinals (Cardinalis cardinalis) ... urban forests than it is for those in rural forests. ...
... Penetrating pores . . . Using neutron scattering ... of the country, Larry Anovitz, David Cole and Gernot Rother ... geologic processes. The researchers are especially interested in studying how ... can range from nano-scale to room-size and are a primary ...
Cached Biology News:Study: The bright red of cardinals means less in urban areas 2Story tips from the US Department of Energy's Oak Ridge National Laboratory, September 2010 2Story tips from the US Department of Energy's Oak Ridge National Laboratory, September 2010 3
(Date:8/21/2014)... 2014 ... the addition of the  "Global Hormone Replacement ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ,Hormone replacement ... a means of replacing hormones that are ... This type of therapy is usually initiated ...
(Date:8/21/2014)... New Rochelle, N.Y. (PRWEB) August 21, 2014 ... it is the first private college in the Mid-Hudson ... The College will now begin accepting applications from qualified ... , “We are very pleased to have been ... to support Governor Cuomo’s transformative initiative to stimulate economic ...
(Date:8/21/2014)... NEW YORK , Aug. 21, 2014 /PRNewswire/ ... OTCM) congratulates Immune Pharmaceuticals Inc., a biotechnology company, ... Capital Market.  Immune previously traded on OTCQX®, the ... operated by OTC Markets Group. Logo - ... Immune Pharmaceuticals on the successful execution of its ...
(Date:8/21/2014)... Chester, NJ (PRWEB) August 21, 2014 ... of personal selling optimization technology and services for ... publication of “Grading Pharma’s Use of New Commercial ... of Measurement & Analytics. , The article examines ... marketing yield that are being tested in the ...
Breaking Biology Technology:Global Hormone Replacement Therapy Market 2014-2018: Key Vendors are Actavis, Bayer, Merck & Co, Novartis and Novo Nordisk 2The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 2The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 3OTC Markets Group Congratulates Immune Pharmaceuticals on NASDAQ Listing 2Pursuit's Peter Robinson Publishes "Grading Pharma's Use of New Commercial Sales Models" 2
... 14 (http://www.amdl.com ) AMDL,Inc., (Amex: ADL ... in China and the US, announced that the,AMDL-ELISA DR- ... useful test for the,detection of cancer in clinical practice ... Medical Department II at the University Hospital,in Frankfurt Germany. ...
... Liquids) will be held in Göteborg, Sweden on October 13-14, 2008 ... discussing commercialization of BTL. Technological advancements & worldwide growth of BTL ... insights on biomass to liquid industry prospect , ... ...
... Rankings Include 170 Hospitals and Medical Centers in 16 Specialties, ... 19 Hospitals Included in ... Group today,announced the 2008 publication of America,s Best Hospitals, accessible,today ... July 14., Authoritative and influential, the 2008 America,s Best ...
Cached Biology Technology:AMDL ELISA DR-70(R) (FDP) is Promising as Effective Cancer Detection Test 2AMDL ELISA DR-70(R) (FDP) is Promising as Effective Cancer Detection Test 3Will New Technological Advances Offer Fresh Capabilities for Commercialization and Enhance BTL Investments? 2Will New Technological Advances Offer Fresh Capabilities for Commercialization and Enhance BTL Investments? 3U.S. News Media Group Releases 19th Edition of America's Best Hospitals 2U.S. News Media Group Releases 19th Edition of America's Best Hospitals 3
Raised to 5-HIAA coupled to BSA with paraformaldehyde....
Request Info...
NuCycl DAPI Kit Application: Flow Cytometry Reactivity: Human...
Anti-hamster Ig HRP detection kit...
Biology Products: