Navigation Links
First in the world - Singapore scientists discover genes responsible for cornea blindness
Date:1/16/2013

atening conditions. Eye doctors can in the future through genetic analysis better manage such patients, preventing regression of their conditions.

Prof Aung Tin, Deputy Director, Singapore Eye Research Institute (SERI) and a senior consultant ophthalmologist and Head of Glaucoma Service at Singapore National Eye Centre and a co-author of the paper, said, "This was a tremendous achievement, involving many centres from several countries around the world. Singapore played a major role in this work, especially SERI's population based studies of 10,000 Chinese, Malay and Indian people."

Assoc Prof Eranga Vithana, Associate Director, Basic and Experimental Sciences, SERI and a co-author of the paper, said, "This paper identified 6 novel genetic variants that confer increased risk of keratoconus, a condition for which genes were not very forthcoming prior to this study. It once again underlined the inevitability of large scale collaborative studies to unravel genes for common complex diseases and also the advantage of having well characterized large cohorts."

Assistant Professor Khor Chiea Chuen, Principal Investigator, Division of Human Genetics, Genome Institute of Singapore-an institute of the Agency for Science, Technology and Research (A*STAR) and the paper's co-lead author, said, "Yet again, this paper underscores the power of modern genetic approaches studied in very large sample sizes in revealing the hereditable basis of normal human traits, and how the extremes of which may give rise to common diseases."

Prof Ng Huck Hui, Executive Director of the Genome Institute of Singapore said, "I am very pleased that the Genome Institute of Singapore is a part of an international effort to dissect the genetics of eye conditions such as keratoconus and glaucoma. Genomics remains a very powerful tool to identify the link between genetic variations and phenotypes. This study that focuses on central corneal thickness illustrates the value
'/>"/>

Contact: Winnie Lim
limcp2@gis.a-star.edu.sg
656-808-8013
Agency for Science, Technology and Research (A*STAR), Singapore
Source:Eurekalert

0

GOOD

Page: 1 2 3

Related biology news :

1. F1000Research, the first Open Science publisher, launches following a successful beta testing phase
2. DNA prefers to dive head first into nanopores
3. First fossil bird with teeth specialized for tough diet
4. The first genome sequence of Chinese plum provides important resource for fruit improvement
5. OpGen announces sequence assembly and finishing of first reference genome of domestic goat
6. The first goat genome sets a good example for facilitating de novo assembly of large genomes
7. First freshwater mosasaur discovered
8. First evidence of fish sensing geomagnetic fields from a Czech Christmas market
9. Africas Homo sapiens were the first techies
10. Surgical Theater, LLC sells first Surgical Rehearsal Platform to UH Case Medical Center
11. First evidence of ocean acidification affecting live marine creatures in the Southern Ocean
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... Wis. In an age when microbial pathogens are ... tamp down infection, a team of Wisconsin scientists has ... curbing the bacteria that cause staph infections. , Writing ... Society , a group led by University of Wisconsin-Madison ... with the "quorum sensing" behavior of Staphylococcus aureus ...
(Date:5/22/2013)... to improve durability in fuel cell powered buses, ... discovered links between electrode degradation processes and bus ... effects of electrode degradation stressors in the operating ... , The findings of the study, led by ... in a long-term study at Burnaby-based Ballard Power ...
(Date:5/22/2013)... 2013)The omega 3 fatty acids in fish oil have ... so that the American Heart Association currently recommends eating ... fatty varieties rich in omega 3s. However, the mechanism ... a new study, scientists led by Jason R. Carter ... by providing evidence that fish oil might specifically counteract ...
Breaking Biology News(10 mins):University of Wisconsin chemists find new compounds to curb staph infection 2Tests lead to doubling of fuel cell life 2Fish oil may help the heart beat mental stress 2
... discovered molecular mechanism helps control the amount and effectiveness of ... that is produced by the body,s own nerve cells. ... Nature Neuroscience . The lead author on the study is ... the University of Washington (UW). The senior author is Dr. ...
... outdoor "laboratory" on Ohio State University,s campus shows that naturally ... ecological services as will wetlands planted by humans. Researchers ... experimental marshes on the campus, one that was planted in ... colonize plant and animal life on its own. The 2 ...
... ITHACA, N.Y. Apathetic aphids which become ... and alarms sent by fellow aphids become easy ... to researchers at the Boyce Thompson Institute for Plant ... Academy of Sciences , Aug. 3, 2010.) The ...
Cached Biology News:Newly discovered mechanism controls levels and efficacy of a marijuana-like substance in the brain 2Newly discovered mechanism controls levels and efficacy of a marijuana-like substance in the brain 3Planted, unplanted man-made wetlands are similar at year 15, and function as effective carbon sinks 2Planted, unplanted man-made wetlands are similar at year 15, and function as effective carbon sinks 3Planted, unplanted man-made wetlands are similar at year 15, and function as effective carbon sinks 4Apathetic aphids with attitude become easier prey for ladybugs 2
(Date:5/23/2013)... Ind. , May 23, 2013  Rahal Letterman ... in human cord blood stem cell banking and therapeutics, ... of the No. 16 Acorn Stairlifts Indy car driven ... for the remainder of the IZOD IndyCar 2013 season. ... (RLL) will work to support awareness of umbilical cord ...
(Date:5/23/2013)... 2013 PI’s new LPS-24 positioners ... 15 mm travel range with closed-loop sensor resolution ... make these new positioners the ideal choice for ... rated version is also available. , More ... can be found at: , http://www.physikinstrumente.com/en/products/prdetail.php?sortnr=1000745&prw-lps24 ...
(Date:5/23/2013)... May 23, 2013  Saddleback Memorial Medical Center in ... the first hospital on the West Coast to perform ... surgical option provides women with a state-of-the-art, minimally invasive ... Marc Winter , M.D., a highly regarded ... medical director of minimally invasive surgery at Saddleback Memorial, ...
(Date:5/23/2013)... , May 23, 2013 BioTrends Research ... advisory firms for specialized biopharmaceutical issues, finds that, ... infectious disease specialists reported that in the past ... intentionally delaying treatment) in anticipation of the next ... months ago, when only 6 percent reported that ...
Breaking Biology Technology:StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 2StemCyte, Inc. Joins Rahal Letterman Lanigan Racing As Associate Sponsor Of No. 16 IndyCar Program For James Jakes Beginning With The 97th Indianapolis 500 3Precision Positioning System Uses Miniaturezed Piezo Linear Motor: LPS-24 Linear Stage by PI 2Saddleback Memorial Surgeon First on the West Coast to Perform Single-Site Robotic Hysterectomy 2Saddleback Memorial Surgeon First on the West Coast to Perform Single-Site Robotic Hysterectomy 3The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 2The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 3
... of Missouri officials announced today a five-year agreement with ... research and training in nanomedicine and nanotechnology. "We ... affiliation of 16 institutions of higher education in Tamil ... research. "K.S.R. has the same commitment to deliver quality ...
... Mich., Oct. 11, 2011 New England Biolabs, Inc. ... signed a distribution agreement whereby NEB will distribute a ... the amplification of DNA from single cells or extremely ... Genome Amplification (WGA) Kit is the first product available ...
... 11, 2011 Roche ( SIX: RO, ... announced today an agreement to license several technologies developed ... Arizona State University and Dr. Colin Nuckolls of the ... revolutionary DNA sequencing system. The licensed technologies include specialized ...
Cached Biology Technology:MU signs academic agreement with K.S.R. Educational Institutions of India 2New England Biolabs and Rubicon Genomics Enter into Distribution Agreement for Single Cell Amplification Products 2Roche Licenses Nanopore Sequencing Technologies from Arizona State University and Columbia University for Rapid, Affordable DNA Sequencing 2Roche Licenses Nanopore Sequencing Technologies from Arizona State University and Columbia University for Rapid, Affordable DNA Sequencing 3Roche Licenses Nanopore Sequencing Technologies from Arizona State University and Columbia University for Rapid, Affordable DNA Sequencing 4
... The Helios gene gun low-pressure system, 220-240 ... biomaterials into cells. This handheld device employs an ... other biomaterial-coated gold microcarriers from the inner wall ... cells. This system can be used for in ...
... Hybridization Wash Pack provides optimized blocking ... Preparation Quality Clarifier: Ready-to-use wash solutions ... SigmaScreen(tm) APS Coated Slides for Microarrays ... Hybridization Blocking Buffer: 1L • Microarray ...
Mouse polyclonal antibody raised against a partial recombinant MHC2TA. NCBI Entrez Gene ID = 4261...
Mouse monoclonal antibody raised against a partial recombinant JRKL. NCBI Entrez Gene ID = JRKL...
Biology Products: