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First-in-man study demonstrates the therapeutic effect of RNAi gene silencing in cancer treatment
Date:2/11/2013

Sloan-Kettering Cancer Center (New York), plus two other Spanish centres -- the Hospital Virgen del Roco in Seville and the INCLIVA Health Research Institute in Valencia -- is potentially transformative for new drug discovery that will allow targeted, population-based studies.

Knowledge of the molecular biology of cancer has expanded greatly over the past decade, leading to the identification of potential therapeutic agents for developing tumour-selective drugs.

The Research Unit for Molecular Therapy of Cancer - "la Caixa", conducts Phase I clinical trials for new anticancer drugs. The choice of the most appropriate anticancer drug for each patient depends on a detailed analysis of the specific molecular changes in each tumour. This exciting approach entails a paradigm shift in the individualized treatment of patients.

Clinical trials play a vital role in developing new cancer treatments as they form the basis of scientifically recognised clinical research. Drugs must be proven to be both safe and efficacious in clinical trial volunteers before they can be formally approved by the appropriate government agency.


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Contact: Amanda Wren
awren@vhio.net
34-695-207-886
Vall dHebron Institute of Oncology
Source:Eurekalert

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