Navigation Links
First human gene implicated in regulating length of human sleep
Date:8/13/2009

studied the miniscule creatures' activity and sleep patterns by tracking the frequency of their movements through infrared light.

Next, the team compared the response of the genetically engineered mice and normal mice to the consequence of six hours of sleep deprivation. The engineered mice needed to compensate for their lost sleep to a much lesser extent as seen in nonREM and REM measures than their normal counterparts.

"These changes in sleep homeostasis in the mutant mice could provide an explanation for why human subjects with the mutation are able to live unaffected by shorter amounts of sleep throughout their lives," says Fu.

The next step, she says, is determining the DEC2's precise role. "We know the gene encodes a protein that is a transcriptional repressor and we know it makes the repressor's activity weaker. But we don't know if the weaker repressor is directly related to the shorter amount of sleep, because proteins can have many functions. It could be the protein functions as part of a larger transcriptional machinery, not necessarily as a repressor."

DEC2 could be involved in modulating "sleep quantity" alone, or it could be mediating both "sleep quantity" and "wakefulness-behavioral drive," according to Fu. The latter drive, she says, is critical for the procurement of food, shelter, and mates and could be more potent in individuals with this mutation.

"The mouse model also provides an opportunity to investigate whether there are other behaviors or physiological conditions associated with a short sleep syndrome," says Fu. She suspects there will be.


'/>"/>

Contact: Jennifer O'Brien
jobrien@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Britains first swine-flu trials under way
2. Launch of the first standard graphical notation for biology
3. First human gets new antibody aimed at hepatitis C virus
4. UBC researchers find first-ever wanderlust gene in tiny bony fish
5. Leicester research paves way for first use in Europe of an insect to fight invasive plant
6. Nottinghamshire Police First Law Enforcement Agency to Deploy ForensicSoft in United Kingdom
7. First genetically-engineered malaria vaccine to enter human trials
8. Spallation Neutron Source sees first target replacement
9. Results of national assessment of first responder location systems to be announced Aug. 3
10. LSUHSC shows for first time infant inhalation of ultrafine air pollution linked to adult lung disease
11. Researchers design first model motor nerve system thats insulated and organized like the human body
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... LAS VEGAS , Dec. 18, 2014   ... platform built for the post-password and Internet of Things ... additional seed funding. The venture round was led by ... Pantera Capital, Rimrock Venture Partners, VegasTechFund, and others.  LaunchKey ... the new funding to expand its team and bring ...
(Date:12/17/2014)... 2014 Valencell, a leader in performance biometric ... to industry leaders such as Intel, Jabra, Atlas, and ... wearable products. These products will be showcased at CES ... Vegas . "Our partners choose ... robust – with the clinical data to back it ...
(Date:12/11/2014)... , Dec. 09, 2014 Research and ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has ... in the APAC Region 2015-2019"  report to their ... in this market is advances in technology. With ... upgrade biometric solutions to the latest standard that ...
Breaking Biology News(10 mins):LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 2LaunchKey Raises $3 Million in Additional Funding Led by Metamorphic Ventures 3Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... one of the millions who dread the spring allergy season, ... May 2009 issue of the Journal of Leukocyte Biology ... scientists have identified a previously unknown cellular switch that turns ... study also suggests that at least for some people with ...
... Researchers have detected common plant toxins that affect human ... results from the new study also suggest that smoldering ... reason to keep human exposures to a minimum during ... as alkaloids -- helps researchers understand how they cycle ...
... A wolverine first photographed by a remote-controlled camera on ... closely related to Rocky Mountain populations, according to a ... Their findings are published in the latest edition of ... of hair collected from the first scientifically verified California ...
Cached Biology News:Just in time for spring: Scientists find the cellular on and off switch for allergies and asthma 2Potentially harmful chemicals found in forest fire smoke 2Origins of wolverine in California genetically verified 2
(Date:12/19/2014)... Mass. , Dec. 18, 2014  Decision Resources ... dental biomaterial market will grow moderately through 2023 ... procedures and growing awareness of dental biomaterials all spur ... markets such as China and ... will bring dental procedures within reach for a larger ...
(Date:12/19/2014)... ISN has released its third annual U.S. ... series. With data aggregated from over eight billion U.S. ... online contractor management platform, ISNetworld, this three-part series provides ... The Contractor Performance Benchmarking ... in two industry specific volumes: Oil & Gas, ...
(Date:12/17/2014)... 16, 2014 The Activated Carbon ... which is why IBISWorld updated its original industry research ... benefit from an intensified focus on environmental policy. Over ... emission standards for power plants and a range of ... IBISWorld Industry Analyst Sarah Kahn, “a range of downstream ...
(Date:12/17/2014)... (PRWEB) December 16, 2014 “Never ... at Philipps- Universität Marburg’s Department of Physics, advises ... in the newly released SPIE Women in ... be too shy to ask questions.” , In ... engineering, and mathematics) occupations ranging from university professor ...
Breaking Biology Technology:Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 2Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 3ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 2ISN Releases Third Edition of US Contractor Health & Safety Performance Indicators Publication Series 3Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 2Activated Carbon Manufacturing in the US Industry Market Research Report Has Been Updated from IBISWorld 3Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 2Network, Multitask, Persevere: SPIE Women in Optics Planner Subjects Share from Experience 3
... German . Researchers from Helmholtz-Zentrum Berlin ... are using electric fields to manipulate the property of electrons ... not only improve random access memory in computers, it could ... new kind of memory exploits a phenomenon called "tunnel magnetoresistance" ...
... , BIRMINGHAM, Ala. , Jan. 19 ... comes to cholesterol. According to a new study, a lipoprotein in ... be labeled "bad cholesterol." The landmark study Genetic Variants Associated ... the New England Journal Of Medicine provides the strongest ...
... BANGALORE, India , January 19 , ... A team of cardiac experts led by Dr. N S Devananda, ... performed a major open heart surgery on a 2-year-old baby from Nigeria ... of,Fallot or complex blue baby syndrome. , " Baby ...
Cached Biology Technology:Data at the end of the tunnel 2New Study: Lp(a) Joins LDL as Heart Disease Risk Factor 2New Study: Lp(a) Joins LDL as Heart Disease Risk Factor 32-Year-old Baby With Complex Heart Deformity Undergoes Major Open Heart Surgery at Wockhardt Hospitals, Bangalore - (now a Network Hospital of Fortis) Without any Blood Transfusion 22-Year-old Baby With Complex Heart Deformity Undergoes Major Open Heart Surgery at Wockhardt Hospitals, Bangalore - (now a Network Hospital of Fortis) Without any Blood Transfusion 3
...
... The OneSTrEP Protein Interaction Kit provides ... step method to isolate intact protein ... tedious optimization or multiple purification steps, ... highly selective StrepTactin Superflow Column for ...
Request Info...
... consists of AmnioMAX-C100 Basal ... and AmnioMAX-C100 Supplement (Cat. ... complete with antibiotics and ... requires no further supplementation ...
Biology Products: