Navigation Links
First at-home test for vasectomized men proves to be safe, accurate
Date:11/13/2008

CHARLOTTESVILLE, VA (November 13, 2008) In a report now available online and scheduled to be the cover story of the December 2008 issue of the Journal of Urology, University of Virginia Health System researcher John C. Herr, PhD and his colleagues have confirmed the accuracy and reliability of SpermCheck Vasectomy, the first FDA approved at-home immunodiagnostic test for detecting low concentrations of sperm.

Herr, a professor of Cell Biology and director of UVA's Center for Research in Contraceptive and Reproductive Health, discovered and patented the biomarker on which SpermCheck is based. The newly reported research consisted of a clinical trial and consumer study.

In the clinical trial, researchers used SpermCheck to evaluate a cohort of 144 post-vasectomy semen samples. The test achieved an accuracy rate of 96 percent in identifying whether sperm counts were greater or less than a threshold of 250,000 sperm per ml a level associated with little or no risk of causing pregnancy. SpermCheck proved to be 100 percent accurate in identifying whether sperm counts were greater or less than 384,000 sperm per ml.

According to the World Health Organization Manual on Semen Analysis, normal sperm counts range from 20,000,000/ml to as high as 200,000,000/ml. When the count is below 1,000,000/ml, there is only a remote chance of achieving pregnancy without assisted reproductive techniques such as intra-uterine insemination, in-vitro fertilization and intra-cytoplasmic sperm injection.

In the consumer study of SpermCheck, 109 lay volunteers demonstrated its ease of use. Volunteers obtained the correct or expected test result in every case and achieved a 97 percent correct response rate on a 20-question survey about the test.

Herr, who is now involved in commercializing SpermCheck through a start-up company, believes the product will make it easier for men to comply with post-vasectomy monitoring. Traditionally, the process has involved bringing semen samples to a physician's office or laboratory at two- and three-month intervals after the procedure. Monitoring is important because vasectomies are not 100 percent successful, and men who have had them can experience recanalization, or the spontaneous healing or restoration of the vas deferens, which restores their fertility.

"SpermCheck Vasectomy is similar in size and function to a women's home pregnancy test," Herr says. "It's designed to help couples monitor and confirm that post-vasectomy sperm concentrations have reached infertile levels and avoid any surprises if recanalization occurs."

According to the National Institutes of Child Health and Human Development, some 500,000 men undergo vasectomies in the U.S. each year, making vasectomy the third most popular contraceptive option among the nation's married couples. The National Institutes of Health reports that one in six men over age 35 have had a vasectomy.


'/>"/>

Contact: Ellen McKenna
ellenmckenna@virginia.edu
434-982-4490
University of Virginia Health System
Source:Eurekalert

Related biology news :

1. Washington University scientists first to sequence genome of cancer patient
2. First results from hospital trials testing
3. Scientists achieve first tracking of salmon from headwaters in Rockies through Pacific to Alaska
4. First comprehensive genomic study of common cold reveals new treatment targets
5. Synaptics Reports Record Results for First Quarter of Fiscal 2009
6. Study of polar dinosaur migration questions whether dinosaurs were truly the first great migrators
7. Volcanoes may have provided sparks and chemistry for first life
8. Alzheimers disease research attracts first partner
9. Synaptics to Report First Quarter Results on October 23
10. Digital zebrafish embryo provides the first complete developmental blueprint of a vertebrate
11. Complete Genomics launches, becomes worlds first large-scale human genome sequencing company
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... WASHINGTON , July 20, 2017 Delta (NYSE: ... to board any Delta aircraft at Reagan Washington National Airport (DCA). ... Delta launches biometrics ... Delta,s ... Delta Sky Club is now integrated into the boarding process to ...
(Date:6/23/2017)... and ITHACA, N.Y. , June ... Cornell University, a leader in dairy research, today announced ... designed to help reduce the chances that the global ... onset of this dairy project, Cornell University has become ... Sequencing the Food Supply Chain, a food safety initiative ...
(Date:5/23/2017)... , May 23, 2017  Hunova, the first robotic gym for the ... been officially launched in Genoa, Italy . The first ... and the USA . The technology was developed ... market by the IIT spin-off Movendo Technology thanks to a 10 million ... News Release, please click: ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... ... ... Kapstone Medical is proud to announce that it has reached ... inventors develop and safeguard their latest innovations. The company has grown from a ... clients in the United States and around the world. , Company Founder and ...
(Date:8/15/2017)... ... 15, 2017 , ... The Conference Forum and The Trout ... a series of upcoming panels and events. The partnership culminates with the 4th ... in New York City. , “With our experience in producing the Immuno-Oncology 360° NYC ...
(Date:8/14/2017)... ... , ... The Conference Forum has confirmed the one-day agenda for ... 6, 2017 at the Marriott Copley Place in Boston, MA. , Returning as program ... Strategy, Pfizer Innovative Research Lab, Pfizer, who leads 19 industry speakers in discussing how ...
(Date:8/10/2017)... , ... August 09, 2017 , ... ... help the agriculture industry reach its ideal customers with the right message. Their ... , “As a Midwest company, we realize how crucial the agriculture industry is,” ...
Breaking Biology Technology: