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'First aid' for brain cells comes from blood
Date:4/16/2009

rain tissue. Interleukin 10 (IL 10), a transmitter substance that is produced by the Treg cells, seems to play an important role during a stroke. Mice with no functioning Treg cells that were injected with IL 10 on the first day following a stroke had markedly less brain damage than mice that did not receive IL 10. On the other hand, the transfer of genetically modified Treg cells unable to produce IL-10 offered no protection.

The researchers in Heidelberg are now working on different approaches for translating the protective mechanisms of Treg into future treatment for strokes. "We still need to know a lot more about how the immune cells communicate among themselves and with the brain cells after a stroke in order to develop a treatment plan for patients," says Dr. Roland Veltkamp.


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Contact: Dr. Roland Veltkamp
Roland.Veltkamp@med.uni-heidelberg.de
062-215-67504
University Hospital Heidelberg
Source:Eurekalert

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