Navigation Links
First adhere, then detach and glide forward
Date:12/23/2009

How do one-celled parasites move from the salivary gland of a mosquito through a person's skin into red blood cells? What molecular mechanisms form the basis for this very important movement of the protozoa? A team of researchers headed by Dr. Friedrich Frischknecht, head of a research group at the Department of Infectious Diseases at Heidelberg University Hospital, observed the initial stage of the malaria parasite that is transmitted by mosquitoes with new microscope techniques. They discovered that the parasite continually alternates between phases of rapid gliding and phases of firm adhesion to the surface. The interaction of these two processes probably enables the parasite to move rapidly over a long time, which is necessary for successful transmission of the disease. The research was a colaboration within the CellNetworks cluster of excellence and published in the prestigious journal Cell Host & Microbe.

The CellNetworks cluster of excellence

Researchers from three different disciplines at the CellNetworks cluster of excellence were involved in the study. This is one of the first studies ever in which modern biophysical methods were used to examine parasites. Leading this study were, in addition to Dr. Friedrich Frischknecht of the Parasitology Department, Professor Dr. Ulrich Schwarz from the Institute of Theoretical Physics and Professor Dr. Joachim Spatz from the Institute of Biophysical Chemistry at the University of Heidelberg.

The goal of the CellNetworks cluster of excellence is to describe and understand complex biological networks. It consists of numerous scientific institutions in the Mannheim/Heidelberg region and was founded at the University of Heidelberg in 2006 as part of the excellence initiative of the Deutsche Forschungsgemeinschaft (German Research Foundation) as one of the first excellence institutions in Germany.

How does the motility mechanism of the malaria parasite function
'/>"/>

Contact: Dr. Friedrich Frischknecht
freddy.frischknecht@med.uni-heidelberg.de
49-622-156-6537
University Hospital Heidelberg
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Which came first, the moth or the cactus?
2. First all-African GM crop is resistant to maize streak virus
3. Scientists retrace evolution with first atomic structure of an ancient protein
4. CU-Boulder team discovers first ancient manioc fields in Americas
5. First finding of a metabolite in 1 sex only
6. First orchid fossil puts showy blooms at some 80 million years old
7. First individual genome sequence published
8. U of M begins nations first clinical trial using T-reg cells from cord blood in leukemia treatment
9. UNH becomes first university in nation to use landfill gas as primary energy source
10. Scientists in first global study of poison gas in the atmosphere
11. Weight gain between first and second pregnancies associated with increased odds of male second child
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
First adhere, then detach and glide forward
(Date:8/20/2014)... WORCESTER, MA Using population-based screening outcomes of approximately ... states, including four researchers at the University of Massachusetts ... combined immunodeficiency (SCID) can be successfully implemented across public ... programs published in the Aug. 20 issue of the ... JAMA ) showed the rate of SCID in newborns ...
(Date:8/20/2014)... have discovered that acral melanomas the rare type of ... are genetically distinct from other more common types of skin ... the journal Pigment Cell & Melanoma Research . , ... soles of the feet, nail-beds and other hairless parts of ... not caused by UV damage from the sun. , The ...
(Date:8/20/2014)... pepper causes a burning spiciness that is irresistible to ... pepper,s effect are using their findings to develop a ... can be caused by inflammation or other problems. They ... tested in clinical trials, in ACS, Journal of ... that decades ago, scientists had pegged a compound called ...
Breaking Biology News(10 mins):Newborn screening expansion offers early diagnosis and treatment to infants with SCID 2Newborn screening expansion offers early diagnosis and treatment to infants with SCID 3Scientists learn more about rare skin cancer that killed Bob Marley 2
... that despite the large number of cancer-causing genes already ... Dana-Farber Cancer Institute have linked a previously unsuspected gene, ... role in cancer was made possible by new tools ... authors of the new study. As these tools are ...
... investigator Gary Ruvkun, PhD, is one of three co-recipients of ... by the Albert and Mary Lasker Foundation, the Lasker Awards ... and many Lasker recipients have gone on to win the ... on Friday, Sept. 26. Ruvkun and his co-recipients ...
... Ralph Regula (R-OH) will be presented with the ... Reception on Monday evening, September 15, 2008. They ... the United States Geological Survey (USGS). Representative Dicks ... Interior, Environment and Related Agencies and Representative Ralph ...
Cached Biology News:Researchers identify cancer-causing gene in many colon cancers 2MGH researcher Gary Ruvkun named a co-recipient of the Lasker Award 2MGH researcher Gary Ruvkun named a co-recipient of the Lasker Award 3USGS Coalition to honor Reps. Dicks, Regula with Leadership Award 2
(Date:8/21/2014)... (PRWEB) August 21, 2014 Ontotext ... today by Ontotext . Now the same ... analysis of structured and unstructured data is available to ... cost of enterprise technology. Organizations that do not have ... data management can use S4 since there is no ...
(Date:8/21/2014)... 2014 SoundConnect , a ... as one of the nation’s Fastest Growing Private ... the 2nd consecutive year. Inc. magazine today ranked ... 500|5000, an exclusive ranking of the nation's fastest-growing ... look at the most important segment of the ...
(Date:8/20/2014)... , Aug. 20, 2014 Clintrax ... services located in Raleigh, NC ... Evans as Vice President of Administration. ... will oversee all corporate processes, including their alignment ... Clintrax Global, Brad worked as an HR executive, ...
(Date:8/20/2014)... often have it that American Indians largely were wiped ... influenza and tuberculosis brought to the New World by ... 20 million people lived in the Americas shortly before ... killed by European diseases., But new research led by ... Johannes Krause of the University of Tubingen in Germany ...
Breaking Biology Technology:Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 2Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 3Ontotext Releases Text Mining & Semantic Technology Running in the Cloud – Welcome to “S4? 4SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3Clintrax Global, Inc. Announces Addition to Executive Team 2Unusual discovery leads to fascinating tuberculosis theory 2Unusual discovery leads to fascinating tuberculosis theory 3
... , SAN CARLOS, Calif., Sept. 21 Nektar Therapeutics ... call to discuss today,s announcement of a new partnership for NKTR-118 and NKTR-119. ... Time (PT). , , The live audio-only Webcast of the ... home page of Nektar,s website: http://www.nektar.com . The web broadcast ...
... , LONDON and SAN CARLOS, ... announced today that they have entered into an exclusive worldwide ... stage investigational product being evaluated for the treatment of opioid-induced ... is intended to deliver products for the treatment of pain ...
... FreezerPro ... and Liquid Nitrogen Tank samples and efficiently manage data of any kind associated with ... ... of FreezerPro 2010, Frozen sample inventory and information management system (FSIIMS). FreezerPro 2010 is ...
Cached Biology Technology:Nektar Therapeutics to Host Conference Call to Discuss Today's Announcement of a New Partnership for NKTR-118 and NKTR-119 2AstraZeneca and Nektar Sign Worldwide Agreement for Nektar Drug Development Programmes -- NKTR-118 and NKTR-119 -- to Address Opioid-Induced Constipation 2AstraZeneca and Nektar Sign Worldwide Agreement for Nektar Drug Development Programmes -- NKTR-118 and NKTR-119 -- to Address Opioid-Induced Constipation 3AstraZeneca and Nektar Sign Worldwide Agreement for Nektar Drug Development Programmes -- NKTR-118 and NKTR-119 -- to Address Opioid-Induced Constipation 4AstraZeneca and Nektar Sign Worldwide Agreement for Nektar Drug Development Programmes -- NKTR-118 and NKTR-119 -- to Address Opioid-Induced Constipation 5RURO Inc. Today Announced the Release of FreezerPro 2010, Frozen Sample Inventory and Information Management System 2
Mouse monoclonal [YPF19] to Yersinia pestis ( Abpromise for all tested applications)....
... extracts cytosolic proteins from mammalian ... their phosphorylation state. The reagent, ... Protein Extraction reagent, includes four ... with Western blotting, immunoprecipitations, and ...
... The features we add to WinList ... the product every day. Features like automatic ... are the result of good suggestions, thoughtful ... of the features you depend on are ...
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX). [Source:Uniprot/SWISSPROT;Acc:P11441] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
Biology Products: