Navigation Links
Firefly protein lights pathway to improved detection of blood clots
Date:12/8/2010

The enzyme that makes fireflies glow is lighting up the scientific path toward a long-sought new medical imaging agent to better monitor treatment with heparin, the blood thinner that millions of people take to prevent or treat blood clots, scientists are reporting. Their study appears in the ACS' monthly journal Bioconjugate Chemistry.

Bruce Branchini and colleagues describe a need for new medical imaging agents that emit near-infrared light the light rays that "night vision" technology detects, enabling soldiers to see in the dark. Those rays penetrate deeper into the body and could give doctors a better way of detecting the proteins involved in blood clotting. Scientists already use luciferase, the enzyme that makes lightning bugs glow, in laboratory research.

The new study describes an advance toward using luciferase in medical imaging. The scientists combined a protein obtained from firefly luciferase with a special dye that allows the protein to emit near-infrared light. In laboratory experiments, the new material successfully detected minute amounts of a specific blood protein, called factor Xa, which is used to monitor the effectiveness of heparin treatment. It offers promise for improved monitoring of heparin therapy, the article suggests.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Dynamics of chaperone protein critical in rescuing brains of Alzheimers mice from neuron damage
2. SomaLogic researchers describe revolutionary new approach to protein analysis and application to early diagnosis of lung cancer
3. Proteins, like people, act differently when crowded together
4. MIT biologists find that restoring the gene for cancer protein p53 slows spread of advanced tumors
5. Uptake protein acts as zincs doorway to the cell
6. Modulating a protein in the brain could help control Alzheimers disease
7. Process leading to protein diversity in cells important for proper neuron firing
8. A stem cell secreted protein can be given to improve heart function after experimental heart attack
9. Structure of a protein related to heart and nervous system health revealed
10. Synapses recycle proteins for the release of neurotransmitters
11. Prima donna protein doesnt work well in pairs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2016)... ... and Markets has announced the addition of the "Global Military Biometrics ... forecasts the global military biometrics market to grow at a CAGR of ... prepared based on an in-depth market analysis with inputs from industry experts. ... coming years. The report also includes a discussion of the key vendors ...
(Date:12/15/2016)... Dec. 15, 2016  There is much more to ... starting the engine. Continental will demonstrate the intelligence of ... Vegas . Through the combination of the keyless ... and biometric elements, the international technology company is opening ... and authentication. "The integration of biometric elements ...
(Date:12/12/2016)... , Dec. 12, 2016  Researchers at Trinity ... for graphene by combining the material with Silly ... sensitive pressure detector able to sense pulse, blood ... small spider.  The research team,s ... be read here:  http://science.sciencemag.org/content/354/6317/1257 ...
Breaking Biology News(10 mins):
(Date:1/23/2017)... , Jan. 23, 2017 /PRNewswire/ - Resverlogix Corp. ... results from the New Zealand ... patients. The data showed remarkable results in reducing inflamed ... healthy control patients. It is believed that this is ... connection of this type can be made between epigenetic ...
(Date:1/23/2017)... PA (PRWEB) , ... January 23, 2017 , ... ... Thomas has been appointed Vice President, Preclinical Safety and Senior Director, Safety Pharmacology. ... of Madras in India. , Dr. Thomas’ career as an academic and ...
(Date:1/23/2017)... ... January 23, 2017 , ... AxioMed will be ... (CANS) annual meeting in Montego Bay, Jamaica from January 26-28th. “We’re excited to ... for surgeons to experience the simplicity of the surgical technique,” said Jake Lubinski, ...
(Date:1/21/2017)... ... January 20, 2017 , ... G&L Scientific Inc, a ... ( http://www.gandlscientific.com ), has announced the opening of new offices in Cambridge, Massachusetts, ... and contractors. This is the latest step in G&L’s expansion of its global ...
Breaking Biology Technology: