Navigation Links
Firefly protein lights pathway to improved detection of blood clots
Date:12/8/2010

The enzyme that makes fireflies glow is lighting up the scientific path toward a long-sought new medical imaging agent to better monitor treatment with heparin, the blood thinner that millions of people take to prevent or treat blood clots, scientists are reporting. Their study appears in the ACS' monthly journal Bioconjugate Chemistry.

Bruce Branchini and colleagues describe a need for new medical imaging agents that emit near-infrared light the light rays that "night vision" technology detects, enabling soldiers to see in the dark. Those rays penetrate deeper into the body and could give doctors a better way of detecting the proteins involved in blood clotting. Scientists already use luciferase, the enzyme that makes lightning bugs glow, in laboratory research.

The new study describes an advance toward using luciferase in medical imaging. The scientists combined a protein obtained from firefly luciferase with a special dye that allows the protein to emit near-infrared light. In laboratory experiments, the new material successfully detected minute amounts of a specific blood protein, called factor Xa, which is used to monitor the effectiveness of heparin treatment. It offers promise for improved monitoring of heparin therapy, the article suggests.


'/>"/>

Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related biology news :

1. Dynamics of chaperone protein critical in rescuing brains of Alzheimers mice from neuron damage
2. SomaLogic researchers describe revolutionary new approach to protein analysis and application to early diagnosis of lung cancer
3. Proteins, like people, act differently when crowded together
4. MIT biologists find that restoring the gene for cancer protein p53 slows spread of advanced tumors
5. Uptake protein acts as zincs doorway to the cell
6. Modulating a protein in the brain could help control Alzheimers disease
7. Process leading to protein diversity in cells important for proper neuron firing
8. A stem cell secreted protein can be given to improve heart function after experimental heart attack
9. Structure of a protein related to heart and nervous system health revealed
10. Synapses recycle proteins for the release of neurotransmitters
11. Prima donna protein doesnt work well in pairs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... easy to ignore, but they are the ultimate source ... Humans are increasingly dependent on algae, too, to suck ... it to the bottom of the ocean. Now, by ... researchers have evidence showing that viruses infecting those algae ... even when all else stays essentially the same, and ...
(Date:8/21/2014)... Nine researchers from Beth Israel Deaconess Medical ... "The World,s Most Influential Scientific Minds 2014," ... Reuters ScienceWatch, a web resource for science metrics and ... as among the most influential "are performing and publishing ... advancement of their science," according to a Thomson Reuters ...
(Date:8/21/2014)... WHEN: , Saturday to Wednesday, Oct. 18-22, 2014 ... 111 W. Harbor Drive, San Diego, CA 92101 ... sessions and other presentations of the latest research ... Opening plenary session featuring high-scoring abstracts on rare ... of various cancers, and treatment for sun sensitivity ...
Breaking Biology News(10 mins):Viruses take down massive algal blooms, with big implications for climate 2BIDMC researchers named among 'the most influential scientific minds' 2BIDMC researchers named among 'the most influential scientific minds' 3American Society of Human Genetics 2014 Annual Meeting 2
... for recent global warming and the rise in sea levels. ... found that this same increase in CO 2 may ... the planet,s most valuable ecosystemswetlands. The team,s findings are being ... Sciences the week of March 23. The team ...
... Mittermeier, renowned wildlife biologist and president of Conservation ... annual Roger Tory Peterson Medal presented by the ... deliver the Roger Tory Peterson Memorial Lecture on ... developing criteria for biodiversity "hotspots" as a conservation ...
... CellThera, a biotechnology company located in Worcester Polytechnic ... Park, has received a contract from the U.S. ... its research program in tissue regeneration. Under the ... of WPI,s Bioengineering Institute (BEI), and the university ...
Cached Biology News:Scientists find climate change to have paradoxical effects in coastal wetlands 2Scientists find climate change to have paradoxical effects in coastal wetlands 3Wildlife biologist named Roger Tory Peterson Medal recipient, speaker 2CellThera and WPI advance in regeneration study 2
(Date:8/21/2014)... SoundConnect , a unified communication ... of the nation’s Fastest Growing Private Companies by ... consecutive year. Inc. magazine today ranked SoundConnect NO. ... exclusive ranking of the nation's fastest-growing private companies. ... the most important segment of the economy—America’s independent ...
(Date:8/20/2014)... , Aug. 20, 2014 Clintrax Global, ... located in Raleigh, NC , ... as Vice President of Administration. ... oversee all corporate processes, including their alignment with ... Global, Brad worked as an HR executive, specializing ...
(Date:8/20/2014)... Grade school history lessons often have it that American ... whooping cough, chicken pox, influenza and tuberculosis brought to ... while estimates vary, about 20 million people lived in ... percent of them were killed by European diseases., But ... Arizona State University and Johannes Krause of the University ...
(Date:8/20/2014)... , Aug. 20, 2014 Neurotrope, ... host a conference call to provide an update ... p.m. Eastern daylight timeDial-in numbers:(888) 505-4369 (U.S. and ... Live web cast: www.neurotropebioscience.com , under "Investor Relations"The ... after completion through September 2, 2014 at (888) ...
Breaking Biology Technology:SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 2SoundConnect Returns on Inc. 5000 List of Fastest Growing Companies 3Clintrax Global, Inc. Announces Addition to Executive Team 2Unusual discovery leads to fascinating tuberculosis theory 2Unusual discovery leads to fascinating tuberculosis theory 3Neurotrope To Host Conference Call 2
... ... Drug safety specialty firm BioSoteria announced that its Vice President ... Performance™ (CPLP) credential from the American Society for Training and Development ... of medical communications and health care training experience and is responsible ...
... ... of interest to anyone working in continuous flow chemistry processing, will deal with the application ... Professor Ley,s work of over 670 publications has been recognized with several prestigious prizes ... ...
... , PETERSBURG, Va., Nov. 4 Star Scientific, ... the company plans to introduce the CigRx(TM) nutraceutical product developed ... sales in partnership with inVentiv Health, Inc ... of commercialization solutions for every stage of the product lifecycle, ...
Cached Biology Technology:BioSoteria eLearning Executive Michelle Nolin Flewell Earns Certification 2BioSoteria eLearning Executive Michelle Nolin Flewell Earns Certification 3BioSoteria eLearning Executive Michelle Nolin Flewell Earns Certification 4Professor Steven Ley of University of Cambridge will Present Free Webinar, 'Application of the ReactIR Flow Cell to Continuous Processing Technology' 2Professor Steven Ley of University of Cambridge will Present Free Webinar, 'Application of the ReactIR Flow Cell to Continuous Processing Technology' 3Star Scientific Plans Worldwide Marketing and Sales of CigRx(TM) Nutraceutical in Partnership with inVentiv Health 2Star Scientific Plans Worldwide Marketing and Sales of CigRx(TM) Nutraceutical in Partnership with inVentiv Health 3Star Scientific Plans Worldwide Marketing and Sales of CigRx(TM) Nutraceutical in Partnership with inVentiv Health 4
...
The Discovery Series PDQuest 2-D analysis software is used for imaging, analyzing, and databasing two-dimensional electrophoretic gels. The 10-user network license entitles ten users to access data f...
Mouse monoclonal antibody raised against a partial recombinant JRKL. NCBI Entrez Gene ID = JRKL...
Mouse monoclonal antibody to ST8SIA2 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2...
Biology Products: