Navigation Links
Fireflies and jellyfish help illuminate quest for cause of infertility
Date:3/27/2009

Genes taken from fireflies and jellyfish are literally shedding light on possible causes of infertility and autoimmune diseases in humans.

Scientists are using the luminescent and florescent genes to illuminate cells that produce a hormone linked to conditions, which include rheumatoid arthritis and lupus.

The technique will help scientists track the production of the hormone prolactin, which is crucial in ensuring supplies of breast milk in nursing mothers but can be overproduced by some pituitary tumours, causing infertility.

Prolactin has been linked to more than 300 biological functions. It is believed to play a role in autoimmune diseases, such as lupus and rheumatoid arthritis, as well as in the inflammation of cells and tissues.

Scientists from the Universities of Edinburgh, Manchester and Liverpool harnessed firefly and jellyfish genes, which enable these creatures to emit light, and used them to create a chemical reaction to light up cells expressing prolactin in rats.

The technique means that scientists can identify when and where prolactin is expressed to look at how the hormone works in real time.

Sabrina Semprini, whose study is published in the journal Molecular Endocrinology, said: "The lighting up of cells expressing this hormone will help us to understand its role within the body and could help research looking for treatments for conditions in which prolactin is involved."

The research, funded by the Wellcome Trust, identified cells producing prolactin throughout the body. This included the pituitary gland, the thymus an organ in the chest which helps protect against autoimmunity the spleen and inflammatory cells in the abdominal cavity.


'/>"/>

Contact: Tara Womersley
tara.womersley@ed.ac.uk
44-131-650-9836
University of Edinburgh
Source:Eurekalert

Page: 1

Related biology news :

1. New online report on massive jellyfish swarms released
2. Scientists discover stinging truths about jellyfish blooms in the Bering Sea
3. Fossil record reveals elusive jellyfish more than 500 million years old
4. Invasive Australian jellyfish sighted in Gulf of Mexico in summer 2007
5. Satellites illuminate pollutions influence on clouds
6. Variable light illuminates the distribution of picophytoplankton
7. New technology illuminates protein interactions in living cells
8. Films of Mitchell and Kenyon illuminate lefties decline in Victorian England
9. Understanding soil carbon sequestration: New book presents key concepts
10. Mountain on Mars may answer big question
11. New models question old assumptions about how many molecules it takes to control cell division
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/13/2017)... April 13, 2017 UBM,s Advanced Design and ... will feature emerging and evolving technology through its 3D ... will run alongside the expo portion of the event ... and demonstrations focused on trending topics within 3D printing ... and manufacturing event will take place June 13-15, 2017 at ...
(Date:4/11/2017)... 11, 2017 Research and Markets has announced ... report to their offering. ... global eye tracking market to grow at a CAGR of 30.37% ... Tracking Market 2017-2021, has been prepared based on an in-depth market ... landscape and its growth prospects over the coming years. The report ...
(Date:4/6/2017)... April 6, 2017 Forecasts by ... Document Readers, by End-Use (Transportation & Logistics, Government & ... Gas & Fossil Generation Facility, Nuclear Power), Industrial, Retail, ... Are you looking for a definitive report ... ...
Breaking Biology News(10 mins):
(Date:4/25/2017)... ... April 25, 2017 , ... Dr. Robert G. Schwartz, the ... announced today that acclaimed physiatrist Matthew Terzella, MD, has joined the practice as ... Dr. Terzella completed his residency in Physical Medicine and Rehabilitation at UMDNJ-Robert Wood ...
(Date:4/24/2017)... -- Dante Labs announced today the offer of whole genome sequencing ... American individuals have been able to access WGS at $1,000, ... below EUR 1,000. The sequencing includes bioinformatics analysis ... make informed decisions about disease monitoring, prevention, nutrition, exercise, health ... ...
(Date:4/21/2017)... ANAHEIM, California, and BELLINGHAM, Washington, USA (PRWEB) , ... ... ... of photonics technologies for sensing, imaging, and related applications were the focus of ... Defense and Commercial Sensing 2017 in Anaheim. , Sponsored by SPIE, ...
(Date:4/20/2017)... ... April 20, 2017 , ... ... this new webinar will explore challenging patient cases when screening for direct oral ... there may be a need for bridging parental anticoagulation especially for those at ...
Breaking Biology Technology: