Navigation Links
Findings on pollution damage to human airways could yield new therapies
Date:1/17/2011

ects of air pollution without grave airway damage.

The injurious molecule MMP-1 is known to enhance the development of certain devastating lung diseases, such as chronic-obstructive pulmonary disease (COPD), a top-ten ailment in world-wide morbidity and mortality, according to the World Health Organization. The devastating, tissue-destructive actions of MMP-1 can also lead to lung emphysema, which is chronic reduction of the lung surface dedicated to gaseous exchange, and to the spread of lung cancer cells, through migration of these cells from lung tissue that has become cancerous.

The new study also provides a direction for developing therapeutics for those who are genetically more susceptible to air pollution and airway damage, Liedtke said. "If we can find a way to stop the hyperactivation of MMP-1 in response to diesel-engine exhaust particles and reduce it to levels that the airways can manage, then we will be helping a large number of people worldwide," he said. "It is attractive to envision inhaled TRPV4 inhibitor drugs, rather than swallowing a pill or taking an injection. I envision this as rather similar to inhaled drugs for allergic airway disease that are currently available."


'/>"/>

Contact: Mary Jane Gore
mary.gore@duke.edu
919-660-1309
Duke University Medical Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. September 2007 Sumatran earthquakes research findings
2. Findings uncover new details about mysterious virus
3. Nearly a century later, new findings support Warburg theory of cancer
4. New research findings may enable earlier diagnosis of uterine cancer
5. Therapeutic cloning gets a boost with new research findings
6. International climate change researchers meet, review latest findings
7. Findings show insulin -- not genes -- linked to obesity
8. FANTOM findings boost for biologists
9. New findings in taste and smell
10. SRI International announces findings from new upper atmospheric radar system for scientific research
11. USC researchers present diabetes findings at American Diabetes Association Scientific Sessions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2015)... 23, 2015 Aware, Inc. (NASDAQ: AWRE ), ... financial results for its second quarter ended June 30, 2015.  ... was $4.5 million, a decrease of 33% compared to $6.8 ... the second quarter of 2015 was $0.3 million, or $0.01 ... per diluted share, in the same period a year ago.  ...
(Date:7/21/2015)... 2015 Passwords have proven futile for ... recent U.S. Office of Personnel Management breach. Biometric ... conundrum, but developers and end-users are concerned about ... dilemma, Biometrics-as-a-Service provider HYPR Corp. announced today the ... third party integration. A video ...
(Date:7/9/2015)... Calif. , July 9, 2015  Synaptics Inc. (NASDAQ: ... solutions, announced today that it will report financial results ... Thursday, July 30, 2015 after the close of market. ... analysts and investors at 2:00 p.m. PT (5:00 p.m. ... To participate on the live call, analysts ...
Breaking Biology News(10 mins):Aware, Inc. Reports Second Quarter 2015 Financial Results 2Aware, Inc. Reports Second Quarter 2015 Financial Results 3Aware, Inc. Reports Second Quarter 2015 Financial Results 4Aware, Inc. Reports Second Quarter 2015 Financial Results 5Aware, Inc. Reports Second Quarter 2015 Financial Results 6HYPR Corp. Launches Industry First Biometric Tokenization Platform 2HYPR Corp. Launches Industry First Biometric Tokenization Platform 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 4Synaptics to Report Fourth Quarter, Fiscal Year 2015 Results on July 30 2
... agree that obesity prevention should begin before children enter school. ... care providers often have trouble advising parents about which interventions ... be published in The Journal of Pediatrics suggests ... effective way to help prevent obesity. Dr. Robert Whitaker ...
... sources near Michigan public schools jeopardizes children,s health ... from University of Michigan researchers. The researchers ... state,s highest industrial air pollution levels had the ... as the highest proportions of students who failed ...
... Access to Research Careers) Program has announced the travel ... (GSA) Mouse Genetics conference in Washington, DC from June ... the entry of underrepresented minority students, postdoctorates and scientists ... to encourage the participation of young scientists at the ...
Cached Biology News:Study suggests prolonged bottle feeding increases the risk of obesity 2Air pollution near Michigan schools linked to poorer student health, academic performance 2Air pollution near Michigan schools linked to poorer student health, academic performance 3Air pollution near Michigan schools linked to poorer student health, academic performance 4
(Date:8/3/2015)... ... August 03, 2015 , ... ... is processed to get such derivatives as ethylbenzene, a precursor to styrene, used ... within the automotive industry for the production of tyres and other components. Thus, ...
(Date:8/3/2015)... DIEGO , Aug. 3, 2015  Aethlon Medical, Inc. ... biofiltration devices to treat life-threatening diseases, today announced that ... conference call and webcast on Thursday, August 13, 2015 ... and webcast will follow the release of fiscal 2016 ... will be available approximately two hours after the call ...
(Date:8/3/2015)... -- According to a new market report ... Asia to Witness Highest Growth by ... culture market was valued at US$ 586.1 Mn in 2014 ... 29.1% to account for US$ 2,717.6 Mn by 2020. ... 3D cell culture refers to a process ...
(Date:7/31/2015)... , July 31, 2015 In today,s ... that help them drive positive health outcomes, improve ... source of patient care in their communities. At ... tradeshow and conference, AmerisourceBergen announced a new set ... Services Administration Organization and help independent pharmacies endure ...
Breaking Biology Technology:World Benzene Market to Surpass 46 MMT by 2020, According to TechSci Research Report Published at MarketPublishers.com 2World Benzene Market to Surpass 46 MMT by 2020, According to TechSci Research Report Published at MarketPublishers.com 3Aethlon Medical To Host First Quarter Fiscal 2016 Investor Call on August 13, 2015 2Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 2Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 3Global 3D Cell Culture Market Will Reach US$ 2,717.6 Million by 2020: Persistence Market Research 4AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 2AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 3
... Laboratories,Inc., a wholly-owned subsidiary of Takara Bio Inc., ... in Chemistry; Drs. Osamu Shimomura, Martin,Chalfie, and Roger ... the green,fluorescent protein (GFP) and a wide array ... as a research tool has,revolutionized life science research ...
... 14 Imaging,Diagnostic Systems, Inc., (OTC Bulletin Board: ... systems, announced today that its,distributor, Laszlo Meszaros of ... Mammography (CTLM(R)) system for Budapest, Hungary., (Logo: ... will be installed at the new MeDoc HealthCare ...
... (OTC,Bulletin Board: PKTX), a biotech company focused ... anti-aging glycopeptides,(AAGPs(TM)), announced today that it has ... of National Financial Communications Corp.,(NFC), to direct ... AAGP(TM) platform technology is ideal for a ...
Cached Biology Technology:Clontech Laboratories, Inc. Recognizes the 2008 Winners of the Nobel Prize in Chemistry 2Imaging Diagnostic Systems Sells Its CT Laser Mammography System to Budapest, Hungary 2ProtoKinetix Partners with OTC Financial Network to Increase Shareholder Base 2ProtoKinetix Partners with OTC Financial Network to Increase Shareholder Base 3
Anti-CD74 Monoclonal Antibody Description: 200 l Research Focus: cell surface antigens Storage: 4C Shipping Temperature: 4C...
NAP-2 (5C7)...
... advanced RACE (rapid amplification of cDNA ends) ... full-length 5' and 3' cDNA ends. The ... Reverse Transcriptase (RT) for improved amplification of ... complex mRNA. The RNase H portion of ...
The Hybrid Hunter Yeast Two-Hybrid System uses the activation of reporter genes to indicate positive protein-protein interactions. Two reporters are used an auxotrophic marker and lacZ....
Biology Products: