Navigation Links
Finding could reduce antibiotic use in critically ill patients
Date:8/3/2011

Measuring the levels of a natural body chemical may allow doctors to reduce the duration of antibiotic use and improve the health outcomes of critically ill patients.

"Infection is a common and expensive complication of critical illness and we're trying to find ways to improve the outcomes of sick, elderly patients and, at the same time, reduce health care costs," says Daren Heyland, a professor of Medicine at Queen's, director of the Clinical Evaluation Research Unit at Kingston General Hospital, and scientific director of the Technology Evaluation in the Elderly Network.

Prolonged antibiotic exposure is associated with an increase in drug-resistant pathogens. It makes sense, according to Dr. Heyland, to examine ways in which we might make the duration of antibiotic treatment more precise without compromising patient outcome.

Dr. Heyland and Queen's research colleagues John Muscedere (School of Medicine) and Ana Johnson (Department of Community Health and Epidemiology) conducted a review of five different studies and found that measuring levels of the chemical procalcitonin (PCT) may be an effective way to monitor the presence of an infection and guide the duration of antibiotic treatment. This is because levels of PCT in the body rise in response to an infection and fall in response to sufficient antibiotic treatment.

The researchers found that using PCT levels to guide antibiotic use means that a course of antibiotics can, on average, be reduced by two days without affecting patient health or length of stay in the intensive care unit. This reduction was also found to be associated with a $470 saving per treatment course ($CDN, 2009). Since infections like ventilator-associated pneumonia are fairly common in hospital intensive care units, this saving on individual treatment courses could translate into significant savings in overall health care costs.

"This study is an example of the kind of technology evaluation
'/>"/>

Contact: Christina Archibald
christina.archibald@queensu.ca
613-533-2877
Queen's University
Source:Eurekalert  

Page: 1 2

Related biology news :

1. New findings on therapeutic hypothermia following cardiac arrest in children
2. Finding is a feather in the cap for researchers studying birds big, powerful eyes
3. Plant pathologist finding Kansas wheat fields a molecular battleground this season
4. Researchers improve method for finding genetic mistakes that fuel cancer
5. Surprising findings from studies of spontaneous brain activity
6. Rochester autism researchers present new findings at IMFAR
7. TGen findings contribute to understanding of diabetic kidney disease
8. Findings may help keep pancreatic disease off the menu
9. Finding shows potential way to protect neurons in Parkinsons, Alzheimers, ALS
10. Finding a way to extend tomato shelf-life
11. Saint Louis University findings: Dont pitch stockpiled avian flu vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Finding could reduce antibiotic use in critically ill patients
(Date:9/2/2014)... When you accidentally touch a hot oven, you rapidly ... neural circuits involved in sensing and responding to such ... players. , Duke researchers have made a surprising discovery ... pain in worms, and have built a structural model ... Nature Communications , may help direct new strategies ...
(Date:9/1/2014)... the U.S. diet showed some modest improvement in the ... in the consumption of unhealthy trans fats, but the ... and the poor. , , An unhealthy diet is ... Eating a healthy diet is an important part of ... trends in diet quality is important because it can ...
(Date:9/1/2014)... the alteration of a single nucleotidethe basic building block of DNAcould ... disability. The study appears in The Journal of Cell ... by a defect in a gene on the X chromosome called ... 230 women and 1 in 360 men carry a so-called premutation, ... the FMR1 gene is slightly longer than normal. These ...
Breaking Biology News(10 mins):Surprising new role for calcium in sensing pain 2Surprising new role for calcium in sensing pain 3Quality of US diet improves, gap widens for quality between rich and poor 2Quality of US diet improves, gap widens for quality between rich and poor 3A nucleotide change could initiate fragile X syndrome 2
... University today announced a partnership to advance the use ... alternative energy source. The effort involves entrepreneurs John ... biodiesel in Afghanistan as a means to achieve multiple ... a new, sustainable economy in the country. ...
... understand the effects of climate change on the microbial ... and the tundra in Alaska, a University of Oklahoma ... of Energy grant. According to Jizhong Zhou, OU ... Institute for Environmental Genomics, the results of these studies ...
... demand for naturally raised beef continues to increase, researchers ... raised beef can be produced effectively for this niche ... to cover additional production and transportation costs. Naturally ... traditional systems take advantage of technologies the industry offers ...
Cached Biology News:Syracuse University partners with Arden-Fox to advance DOD's Net Zero Energy Initiative 2Syracuse University partners with Arden-Fox to advance DOD's Net Zero Energy Initiative 3Can naturally raised beef find its place in the industry? 2
(Date:8/29/2014)... PA (PRWEB) August 29, 2014 Pittcon ... Hub MacDonald, and colleague Koichiro Matsuda, Horiba Scientific, have ... on September 5, 2014. JASIS , Asia’s largest ... 3-5, 2014, in Makuhari Messe, Japan. , The ... Tools for Bioanalysis from Single Molecules to Single Cells” ...
(Date:8/29/2014)... 29, 2014 Local veterinarian, Dr. Keith ... are seeking candidates to participate in an investigational study ... The ultimate goal of this study is to determine ... one or two arthritically affected joints can help reduce ... Candidates for the current investigational study must be older ...
(Date:8/29/2014)... Boston, MA (PRWEB) August 29, 2014 Due ... (FRC) last week, the Adult Stem Cell Technology Center, ... donations to support stem cell therapy research that might benefit ... adult stem cells for new stem cell technologies and therapeutic ... ALS Ice Bucket Challenge donors who wish not ...
(Date:8/29/2014)... August 29, 2014 Intrinsic Imaging, ... certified, GAMP® 5 compliant imaging core lab, announced ... Phase II clinical trial to assess a new ... this trial, Intrinsic Imaging will provide comprehensive imaging ... protocol and charter development, site qualification, site training ...
Breaking Biology Technology:Fifth Annual U.S. Symposium at JASIS Organized by Pittcon’s Program Chairman Hub MacDonald 2Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2The Adult Stem Cell Technology Center, LLC Declines ALS Ice Bucket Challenge Donors Wishing to Support Ethical Research for New Stem Cell Therapies 2The Adult Stem Cell Technology Center, LLC Declines ALS Ice Bucket Challenge Donors Wishing to Support Ethical Research for New Stem Cell Therapies 3Intrinsic Imaging Awarded Phase II Clinical Trial to Assess New Treatment for Non-Hodgkin’s Lymphoma 2
... Wisconsin landed a federal research laboratory too long, many observers might ... Madison in 1910 when Gifford Pinchot, the first chief of the ... National Wildlife Health Center , established in Madison in 1975, has ... race against bird flu. , ,The latest addition is the ...
... NimbleGen Systems scientist Thomas Albert will lead a ... microarray technology in DNA sequence analysis, the company announced. ... be the lead investigator on a two-year, $415,000 grant ... million Cancer Genome Atlas pilot project. , ,His work ...
... the scandals of WorldCom, ENRON, and TYCO were heartless and greedy, ... on this video make them look like saints. Why? Because the ... make a living to support their families. , ,Think about all ... of years that have not been able to find a good ...
Cached Biology Technology:Federal bioenergy lab will give Wisconsin a chance to shine 2Federal bioenergy lab will give Wisconsin a chance to shine 3Federal bioenergy lab will give Wisconsin a chance to shine 4A disgusting video: U.S. companies sell out Americans 2A disgusting video: U.S. companies sell out Americans 3A disgusting video: U.S. companies sell out Americans 4
Borosilicate Glass. Certified for use with the Beacon 2000 Systems, 1,000 tubes/case...
... Engineered with new technology incorporating ... for unsurpassed flexibility, the new Varian ... advanced spectrometer available today., ,The Varian ... each transmitter and receiver channel, providing ...
Luminometers...
... Dr. P Set from different human ... More organs maybe available upon request. ... items from the whole set, and ... price. All Dr. P Set ...
Biology Products: