Navigation Links
Final chapter to 60-year-old blood group mystery
Date:4/7/2013

haemoglobin level confers a risk of anaemia, which is one of the most frequent reasons for an individual to visit their doctor. The team are pursuing further research to deduce how Smim1 protein regulates red blood cell formation.

"As the molecular machinery underlying red blood cell formation has been researched for decades in fish, mice and man, our discovery that a gene which was considered hypothetical until recently actually controls a red blood cell membrane protein with an important role in the regulation of haemoglobin levels is astonishing," says Professor Ellen van der Schoot from the Sanquin research laboratories in Amsterdam. "A better understanding of how the SMIM1 gene is regulated is important and this effort will greatly benefit from the Blueprint project which will be releasing its results on the biology of blood cells and their precursors this year."

"We have worked for nearly a decade to identify the donors across England that lack the Vel blood group so that we can provide matched and safe blood to patients with antibodies against Vel" says Mr Malcolm Needs from NHS Blood and Transplant in Tooting, London. "The discovery of the SMIM1 gene was achieved so quickly and it is truly amazing to see how medical genomics is changing the care landscape for NHS patients."


'/>"/>

Contact: Aileen Sheehy
press.office@sanger.ac.uk
44-012-234-96928
Wellcome Trust Sanger Institute
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. WPI Biomedical Technology in final 4 of international business plan contest
2. Researchers attack HIVs final defenses before drug-resistant mutations emerge
3. Dark matter made visible before the final cut
4. Finalists of air pollution sensor challenge announced
5. NYBG press publishes final volume of landmark Intermountain Flora series
6. Sequencing works in clinical setting to help -- finally -- get a diagnosis
7. Planet under Pressure conference, London: Final statement
8. FASEB MARC Travel Awards announced for the 2013 American College of Sports Medicine Northwest Chapter Meeting
9. UTSA physiologist William Cooke named 2013 Lecture Series Speaker by Texas Sports Medicine Chapter
10. Composite nanofibers developed by Penn scientists next chapter in orthopaedic biomaterials
11. MRI measure of blood flow over atherosclerotic plaque may detect dangerous plaque
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... Until recently, little has been known about what genetic ... team of scientists, one of whom is a University ... showing that genes controlling the development of the brain ... domestication., The study was published Aug. 28 in ... It is online at http://www.sciencemag.org/ ., The domestication ...
(Date:8/29/2014)... German . ... cycle on Earth and in biological wastewater treatment plants. ... on nitrite as their source of energy. An international ... at the University of Vienna, has now shown that ... of energy. The oxidation of hydrogen with oxygen enables ...
(Date:8/29/2014)... twist them, fold them: modern materials that are light, ... as artificial skin or electronic paper. , Making such ... but a new way of working with copper nanowires ... , Previous success in the field of ultra-lightweight ... precious gold and silver nanowires. , By turning ...
Breaking Biology News(10 mins):New research reveals how wild rabbits were genetically transformed into tame rabbits 2New research reveals how wild rabbits were genetically transformed into tame rabbits 3Hydrogen powers important nitrogen-transforming bacteria 2Hydrogen powers important nitrogen-transforming bacteria 3Copper shines as flexible conductor 2
... Massey Cancer Center researchers have uncovered a new mechanism ... stimulate the development of novel regimens in which it ... with blood cancers and solid tumors. , In ... associate director for translational research and co-leader of the ...
... to dressing their children, at least among side-blotched lizards, ... at the University of California, Santa Cruz, have found ... color patterns in their offspring in response to social ... for the rest of their lives. The mother's influence ...
... genetic factors and certain adverse events related to smallpox ... issue of The Journal of Infectious Diseases, now available ... other live vaccines. , Immunization against infectious agents has ... and the eradication of smallpox from the world is ...
Cached Biology News:Researchers shed light on mechanism of action used by anti-cancer drug 2Study shows lizard moms dress their children for success 2Study shows lizard moms dress their children for success 3Study shows lizard moms dress their children for success 4Genetic factors are linked to fever following smallpox vaccination 2
(Date:8/28/2014)... (PRWEB) August 28, 2014 Sterlitech is ... polymeric membranes to its stable of products . ... molecular weight cut-offs and include membrane filters with surface ... increase in customer demand for our membrane process testing ... variety of flat sheet membranes,” explains Sterlitech President Mark ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 A ... around the world is available from Strategic Consulting, ... companies. “ Industrial Microbiology Market Review, Fourth Edition: ... Market ” (IMMR—4) tracks and compares microbiology test ... North America, Europe and Asia, and forecasts future ...
(Date:8/28/2014)... York, NY (PRWEB) August 28, 2014 ... renewed its long term partnership with PTI Inspection ... provide clients with state of the art leak testing ... of the art instruments currently available. As part of ... new High Voltage Leak Detection Instrument developed ...
(Date:8/27/2014)... (PRWEB) August 27, 2014 In ... through Lawrence Livermore National Security LLC ... develop and deliver a state-of-the-art laser system for ... (ELI Beamlines), under construction in the Czech Republic. ... the laser system, called the " High repetition-rate ...
Breaking Biology Technology:Sterlitech Corporation Enhances Its Selection of Flat Sheet Membrane Filters 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3Whitehouse Labs Renews Partnership with PTI Inspection Systems 2Whitehouse Labs Renews Partnership with PTI Inspection Systems 3LLNL Synchs up with ELI Beamlines on Timing System 2LLNL Synchs up with ELI Beamlines on Timing System 3
... Jan. 3 Cambrex,Corporation (NYSE: CBM ) ... President and Chief Executive Officer, will make a ... on January 8, 2008 at,9:00 a.m. PST at ... (Logo: http://www.newscom.com/cgi-bin/prnh/20000613/CAMBREXLOGO ), A live ...
... Thoratec,Corporation (Nasdaq: THOR ), a world leader ... it will be participating in the JP,Morgan Healthcare ... president and chief executive officer, will provide an,update ... Standard Time (11:30,a.m., Eastern Standard Time)., The ...
... Calif., Jan. 3 /Xinhua-PRNewswire-FirstCall/ --,Kiwa Bio-Tech Products ... its Fertilizer Products in Dingxing, Hebei on ... large volume distribution,businesses in 7 counties in ... agreements were reached with local dealers to ...
Cached Biology Technology:Kiwa Bio-Tech Products Group Holds a Fertilizer Products Exhibition in Hebei 2Kiwa Bio-Tech Products Group Holds a Fertilizer Products Exhibition in Hebei 3