Navigation Links
Fighting cancers by tagging their triggers
Date:9/30/2010

Imagine the day a machine can draw your blood, screen it for genetic mutations and chemical variations that can cause cancer, and pop out a drug tailor-made for your DNA.

That hypothetical drug would target and fix - the point irregularities which have accumulated over time that can lead to the formation of tumors and cancer.

The National Institutes of Health has tapped Viterbi professor Andrea Armani to develop a key instrument that takes researchers a step closer to realizing this vision.

"Personalized cancer drug delivery? Depending on the approach, it could be as soon as 10 to 15 years away," says Armani, an assistant professor of the Mork Family Department of Chemical Engineering and Materials Science.

Armani has received the NIH's 2010 New Innovator Award, which recognizes a select group of researchers with "exceptional creativity" and bold approaches that "have the potential to produce a major impact on broad, important problems in biomedical and behavioral research."

The award amounts to a $2.3 million research grant over five years to investigate epigenetics. This field studies changes in DNA which are associated with cancer.

Analysis of these DNA changes has shown promise in the early detection and treatment of ovarian and other types of cancer, says Armani.

But current research methods are only able to capture snapshots of these DNA changes, instead of monitoring the process continuously. Therefore, they miss information that could be vital to understanding processes that have been linked to cancer and other diseases, like Huntington's and diabetes.

The sensitivity or resolution of many of these techniques is also very poor. "It's like trying to watch a TV show through static," says Armani.

Her method will push the field straight to High-Definition.

Armani proposes to develop an ultrasensitive nanolaser that would allow her to detect changes in DNA
'/>"/>

Contact: Eric Mankin
mankin@usc.edu
213-821-1887
University of Southern California
Source:Eurekalert  

Page: 1 2

Related biology news :

1. New infrared light may open new frontier in fighting cancer, Tay Sachs
2. U of Alberta researchers discover important mechanism in fighting infection
3. In the ring: Researchers fighting bacterial infections zero in on microorganisms soft spots
4. Symposium spotlights new paradigms in genomics, celebrates AIDS-fighting drug at 25 years
5. Fighting fungal infections with bacteria
6. UT Southwestern researchers identify key molecular step to fighting off viruses
7. Carbon nanotubes boost cancer-fighting cells
8. New cancer-fighting strategy focuses on signaling molecules
9. Fighting IED attacks with SCARE technology
10. Fighting sleep, Penn researchers reverse the cognitive impairment caused by sleep deprivation
11. Diabetes drug shows promise in fighting lethal cancer complication
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Fighting cancers by tagging their triggers
(Date:12/22/2014)... 22, 2014  NXT-ID, Inc. (NASDAQ: NXTD and ... on the growing mobile commerce market, announces it has retained ... for the 2015 International CES debut of the Wocket™ biometric ... be at the NXT-ID booth January 6th and 7 th ...
(Date:12/19/2014)... and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) has announced the ... Security Systems Market" report to their offering. ... perimeter security market is estimated to grow at a CAGR ... holds a larger share in this market, Canada ...
(Date:12/17/2014)... , Dec. 15, 2014 The Defense Logistics Agency ... detect and prevent counterfeit microcircuits from entering into its ... an in-house microcircuit anti-counterfeit initiative dubbed DNA marking. The ... increasing their reliability throughout the supply chain. The new ...
Breaking Biology News(10 mins):NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 2Defense Logistics Agency Launches DNA Marking Capability to Strengthen Microcircuit Supply Chain 3
... people with asthma, a couple of puffs from an inhaler ... become resistant to the calming effect of that medicine, they ... them to the hospital or worse. Now, ... help explain what,s going on in the lungs of these ...
... European Alps suggests that population declines to be observed ... effects of recent climate warming on mountain plants. A ... Department of Conservation Biology, Vegetation and Landscape Ecology of ... to predict migration of mountain plants which explicitly takes ...
... principle have produced enough of the greenhouse gas methane to ... time when the Earth was warm and wet. That,s according ... Current Biology, a Cell Press publication. The hulking ... were widespread about 150 million years ago. As in cows, ...
Cached Biology News:Scientists discover new type of cell with a key role in treatment-resistant asthma 2Scientists discover new type of cell with a key role in treatment-resistant asthma 3European mountain plant population shows delayed response to climate change 2Gaseous emissions from dinosaurs may have warmed prehistoric earth 2
(Date:1/23/2015)... (PRWEB) January 23, 2015 Portal Solutions ... digital workplaces on Microsoft Office 365 and SharePoint platforms ... 50 Award program for being one of the region’s fastest-growing ... and employee growth. , “To be recognized a second ...
(Date:1/22/2015)... 2015 Shimadzu Scientific Instruments today ... UV-visible spectrophotometer. Offering wavelength scanning from 190 to ... for applications in a variety of industries, including ... user-friendly UV-1280 enables intuitive operation, while the enhanced ...
(Date:1/22/2015)... Bedford, NH (PRWEB) January 22, 2015 ... offers a table top laboratory homogenizer, the PandaPLUS 2000, ... nanoparticles, nanodispersions, nanoemulsions , and cell disruption . ... processing dairy products, fruit juices, liquid food, food additives ...
(Date:1/22/2015)... Cambridge Semantics, the leading provider of smart data solutions driven ... record-breaking year across the board for the company. , ... and our Smart Data solutions, our customers were able to ... to record growth for the company in 2014,” said Alok ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2GEA Niro Soavi Announces the PandaPLUS 2000 Homogenizer for Processing New Applications for Nanoemulsions and Cell Disruption 2Cambridge Semantics Announces Record Results for 2014 2
... March 19, 2012   Organovo Holdings, Inc. (OTCQB: ... oversubscribed $15.2 million private placement. At the final closing, ... the sale of 6.9 million Units, at a price ... has approximately 43.7 million shares of common stock issued ...
... Toby Odenheim, director of IT services at Synteract, ... to present on Selecting the Optimum EDC Platform to ... Clinical Trials, East Coast conference , to be held in ... EDT, Wed., March 28, discussing a variety of drivers to ...
... a note telling you that the product contains L(+)-lactic acid, ... of their atoms. The two"isomers", L(+) and D(-), have different ... right or left respectively. Of course the capacity to alter ... to solutions of yoghurt. Light interacts in one way or ...
Cached Biology Technology:Organovo Announces Close of $15.2 Million Private Placement to Advance 3D Bioprinting for Medical Applications 2Organovo Announces Close of $15.2 Million Private Placement to Advance 3D Bioprinting for Medical Applications 3Synteract Director of IT Services Toby Odenheim Speaking at March 2012 Outsourcing in Clinical Trials East Coast Conference 2Synteract Director of IT Services Toby Odenheim Speaking at March 2012 Outsourcing in Clinical Trials East Coast Conference 3Designer lights from the physics lab 2
... are cytopathic effect inhibition assays, also known as ... tissue culture supernatents; serum from PK studies and ... is defined as the quantity of interferon required ... viral infection by 50%. All standards ...
... Topoisomerase I from vaccinia virus is a ... positive and negative superhelical turns (also called ... DNA. The product of the reaction is ... positive or negative superhelical turns. DNA Topoisomerase ...
... Topoisomerase I from vaccinia virus is ... both positive and negative superhelical turns (also ... closed DNA. The product of the reaction ... fewer positive or negative superhelical turns. DNA ...
... CpGenome Fast DNA Modification Kit contains reagents ... a DNA sample. In the bisulfite reaction, ... converting them to uracils, while 5-methylcytosines remain ... DNA will differ depending on whether the ...
Biology Products: